Cytotoxic pathways in the skin allograft rejection by CD4+ T cells

Transplantation

Volumn 68, Issue 1, 1999, Pages 97-100

  Ito, Akiko ^a   Minagawa, Masahiro ^a   Tomiyama, Katsuhiro ^a   Ito, Masaaki ^a   Kawai, Kazuhiro ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; MONOCLONAL ANTIBODY; PERFORIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CYTOTOXIC T LYMPHOCYTE; CYTOTOXICITY; FULL THICKNESS SKIN GRAFT; GRAFT REJECTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN ALLOGRAFT; T LYMPHOCYTE ACTIVATION;

EID: 0033565410     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/00007890-199907150-00019     Document Type: Article

References (47)

1. Henkart PA. Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules. Immunity 1994; 1: 343.
2. Kägi D, Ledermann B, Bürki K, Zinkernagel RM, Hengartner H. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu Rev Immunol 1996; 14: 207.
3. Henkart PA. Mechanism of lymphocyte-mediated cytotoxicity. Annu Rev Immunol 1985; 3: 31.
4. Kägi D, Ledermann B, Bürki K, et al. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin deficient mice. Nature 1994; 369: 31.
5. Lowin B, Beermann F, Schmidt A, Tschopp J. A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity. Proc Natl Acad Sci USA 1994; 91: 11571.
6. Kojima H, Shinohara N, Hanaoka S, et al. Two distinct pathways of specific killing revealed by perforin mutant cytotoxic T lymphocytes. Immunity 1994; 1: 357.
7. Walsh CM, Matloubian M, Liu C-C, et al. Immune function in mice lacking the perforin gene. Proc Natl Acad Sci USA 1994; 91: 10854.
8. 2+-independent T cell-mediated cytotoxicity. J Exp Med 1993; 177: 195.
9. Nagata S, Golstein P. The Fas death factor. Science 1995; 267: 1449.
10. Kägi D, Vignaux F, Ledermann B, et al. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science 1994; 265: 528.
11. Lowin B, Hahne M, Mattmann C, Tschopp J. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas lytic pathways. Nature 1994; 370: 650.
12. + cytotoxic T cells. Proc Natl Acad Sci USA 1994; 91: 4185.
13. + T cell-mediated cytotoxicity. J Immunol 1994; 152: 1127.
14. Hanabuchi S, Koyanagi M, Kawasaki A, et al. Fas and its ligand in a general mechanism of T-cell-mediated cytotoxicity. Proc Natl Acad Sci USA 1994; 91: 4930.
15. Hahn S, Gehri R, Erb P. Mechanism and biological significance of CD4-mediated cytotoxicity. Immunol Rev 1995; 146: 57.
16. + CTL that utilizes a perforin-rather than a Fas ligand-dependent cytotoxic mechanism. J Immunol 1996; 156: 153.
17. Watanabe-Fukunaga R, Brannan CI, Copeland NG, Jenkins NA, Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apotosis. Nature 1992; 356: 314.
18. Takahashi T, Tanaka M, Brannan CI, et al. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 1994; 76: 969.
19. Rothstein TL, Wang JKM, Panka DJ, et al. Protection against Fas-dependent Th1-mediated apotosis by antigen receptor engagement in B cells. Nature 1995; 374: 163.
20. Mintz B, Silvers WK. "Intrinsic" immunological tolerance in allophenic mice. Science 1967; 158: 1484.
21. Mintz B, Silvers WK. Histocompatibility antigens on melano-blasts and hair follicle cells: cell-localized homograft rejection in allophenic skin grafts. Transplantation 1970; 9: 497.
22. Rosenberg AS, Singer A. Evidence that the effector mechanism of skin allograft rejection is antigen-specific. Proc Natl Acad Sci USA 1988; 85: 7739.
23. Larsen CP, Alexander DZ, Hendrix R, Ritchie SC, Pearson TC. Fas-mediated cytotoxicity. Transplantation 1995; 60: 221.
24. Lu X, Ledermann B, Borel JF. Survival of islet grafts in perforin-deficient mice. Transplant Proc 1995; 27: 3262.
25. Schultz M, Schuurman H-J, Joergensen J, et al. Acute rejection of vascular heart allografts by perforin-deficient mice. Eur J Immunol 1995; 25: 474.
26. Selvaggi G, Ricordi C, Podack ER, Inverardi L. The role of the perforin and Fas pathways of cytotoxicity in skin graft rejection. Transplantation 1996; 62: 1912.
27. Seino K, Kayanagi N, Bashuda H, Okumura K, Yagita H. Contribution of Fas ligand to cardiac allograft rejection. Int Immunol 1996; 8: 1347.
28. Ahmed KR, Guo TB, Gaal KK. Islet rejection in perforin-deficient mice. Transplantation 1997; 63: 951.
29. Perez C, Albert I, DeFay K, Zachariades N, Gooding L, Kriegler M. A nonsecretable cell surface mutant of tumor necrosis factor (TNF) kills by cell-to-cell contact. Cell 1990; 63: 251.
30. + cytotoxic T lymphocyte-mediated lysis. J Immunol 1993; 150: 4303.
31. Braun MY, Lowin B, French L, Acha-Orbea H, Tschopp J. Cytotoxic T cells deficient in both functional Fas ligand and perforin show residual cytolytic activity yet lose their capacity to induce lethal acute graft-versus-host disease. J Exp Med 1996; 183: 657.
32. Ando K, Hiroishi K, Kaneko T, et al. Perforin, Fas/Fas ligand, and TNF-a pathways as specific and bystander killing mechanisms of hepatitis C virus-specific human CTL. J Immunol 1997; 158: 5283.
33. - epidermal cells. J Immunol 1989; 143: 2452.
34. Kawai K, Shahinian A, Mak TW, Ohashi PS. Skin allograft rejection in CD28-deficient mice. Transplantation 1996; 61: 352.
35. Abrams JS, Roncarolo M-G, Yssel H, Andersson U, Gleich GJ, Silver JE. Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples. Immunol Rev 1992; 127: 5.
36. Pfeffer K, Matsuyama T, Kündig TM, et al. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 1993; 73: 457.
37. Tsukada N, Kobata T, Aizawa Y, Yagita H, Okumura K. Graft-versus-leukemia (GVL) effect and graft-versus-host disease (GVHD) can be differentiated by cytotoxic mechanisms in a murine model of allogeneic bone marrow transplantation. Blood 1999; 93: 2738.
38. Chu J-L, Drappa J, Parnassa A, Elkon KB. The defect in Fas mRNA expression in MRL/lpr mice is associated with insertion of the retrotransposon, ETn. J Exp Med 1993; 178: 723.
39. Mariani SM, Matiba B, Armandola EA, Krammer PH. The APO-1/Fas (CD95) receptor is expressed in homozygous MRL/lpr mice. Eur J Immunol 1994; 24: 3119.
40. Zijlstra M, Auchincloss H Jr, Loring JM, Chase CM, Russell PS, Jaenisch R. Skin graft rejection by β2-microglobulin-deficient mice. J Exp Med 1992; 175: 885.
41. + cells in mice after class II-disparate skin graft rejection. Transplantation 1992; 53: 237.
42. Sutton VR, Vaux DL, Trapani JA. Bcl-2 prevents apotosis induced by perforin and granzyme B, but not that mediated by whole cytotoxic lymphocytes. J Immunol 1997; 158: 5783.
43. Liu C-C, Detmers PA, Jiang S, Young JD-E. Identification and characterization of a membrane-bound cytotoxin of murine cytolytic lymphocytes that is related to tumor necrosis factor/ cachectin. Proc Natl Acad Sci USA 1989; 86: 3286.
44. Kinkhabwala M, Sehajpal P, Skolnik E, et al. A novel addition to the T cell repertory: cell surface expression of tumor necrosis factor/cachectin by activated normal human T cells. J Exp Med 1990; 171: 941.
45. Walsh CM, Hayashi F, Saffran DC, Ju S-T, Berke G, Clark WR. Cell-mediated cytotoxicity results from, but may not be critical for, primary allograft rejection. J Immunol 1996; 156: 1436.
46. Smith CA, Farrah T, Goodwin RG. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell 1994; 76: 959.
47. Browing JL, Miatkowski K, Sizing I, et al. Signaling through the lymphotoxin β receptor induces the death of some adenocarcinoma tumor lines. J Exp Med 1996; 183: 867.