CD14 plays no major role in shock induced by Staphylococcus aureus but down-regulates TNF-α production

Journal of Immunology

Volumn 162, Issue 8, 1999, Pages 4801-4805

  Haziot, Alain ^a   Hijiya, Naoki ^a   Schultz, Karine ^a   Zhang, Fan ^a   Gangloff, Sophie C ^a   Goyert, Sanna M ^a  

^a NORTH SHORE UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CD14 ANTIGEN; CYTOKINE; GENTAMICIN; INTERLEUKIN 6; PEPTIDOGLYCAN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CELL WALL; BACTERIAL INFECTION; CONTROLLED STUDY; GRAM POSITIVE BACTERIUM; LETHALITY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; SEPTIC SHOCK; SPLEEN CELL; STAPHYLOCOCCUS AUREUS;

ANIMALS; ANTIGENS, CD14; BACTERIAL CAPSULES; CYTOKINES; DOWN-REGULATION; GENTAMICINS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; SHOCK, SEPTIC; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0033561668     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Bone, R. C. 1991. The pathogenesis of sepsis. Ann. Intern. Med. 115:457.
2. Goyert, S. M., E. Ferrero, W. J. Rettig, A. K. Yenamandra, F. Obata, and M. M. Le Beau. 1988. The CD14 monocyte differentiation antigen maps to a region encoding growth factors and receptors. Science 239:497.
3. Haziot, A., S. Chen, E. Ferrero, M. G. Low, R. Silber, and S. M. Goyert. 1988. The monocyte differentiation antigen, CD14, is anchored to the cell membrane by a phosphatidylinositol linkage. J. Immunol. 141:547.
4. Haziot, A., E. Ferrero, F. Koentgen, N. Hijiya, S. Yamamoto, J. Silver, C. L. Stewart, and S. M. Goyert. 1996. Resistance to endotoxin shock and reduced dissemination of Gram-negative bacteria in CD14-deficient mice. Immunity 4:407.
5. Morrison, D. C., and J. L. Ryan. 1987. Endotoxins and disease mechanisms. Annu. Rev. Med. 38:417.
6. Rietschel, E. T., and H. Wagner. 1996. Bacterial endotoxin: chemical constitution, biological recognition, host response, and immunological detoxification. Curr. Top. Microbiol. Immunol. 216:39.
7. Pugin, J., I. D. Heumann, A. Tomasz, V. V. Kravchenko, Y. Akamatsu, M. Ishijima, M. P. Glauser, P. S. Tobias, and R. J. Ulevitch. 1994. CD14 is a pattern recognition receptor. Immunity 1:509.
8. Weidemann, B., H. Brade, E. T. Rietschel, R. Dziarski, V. Bazil, S. Kusumoto, H.-D. Flad, and A. J. Ulmer. 1994. Soluble peptidoglycan-induced monokine production can be blocked by anti-CD14 monoclonal antibodies and by lipid A partial structures. Infect. Immun. 62:4709.
9. Gupta, D., T. N. Kirkland, S. Viryiyakosol, and R. Dziarski. 1996. CD14 is a cell-activating receptor for bacterial peptidoglycan. J. Biol. Chem. 271:23310.
10. Kusunoki, T., E. Hailman, T. Juan, H. Lichenstein, and S. Wright. 1995. Molecules from Staphylococcus aureus that bind CD14 and stimulate innate immune responses. J. Exp. Med. 182:1673.
11. Cleveland, M. G., J. D. Gorham, T. L. Murphy, E. Tuomanen, and K. M. Murphy. 1996. Lipoteichoic acid preparations of Gram-positive bacteria induce interleukin-12 through a CD14-dependent pathway. Infect. Immun. 64:1906.
12. Cauwels, A., E. Wan, M. Leismann, and E. Tuomanen. 1997. Coexistence of CD14-dependent and independent pathways for stimulation of human monocytes by Gram-positive bacteria. Infect. Immun. 65:3255.
13. Medvedev, A. E., T. Flo, R. R. Ingalls, D. T. Golenbock, G. Teti, S. N. Vogel, and T. Espevik. 1998. Involvement of CD14 and complement receptors CR3 and CR4 in nuclear factor-κB activation and TNFα production induced by lipopolysaccharide and group B streptococcal cell walls. J. Immunol. 160:4535.
14. Melly, M. A., L. J. Duke, D.-F. Liau, and J. H. Hash. 1974. Biological properties of the encapsulated Staphylococcus aureus M. Infect. Immun. 10:389.
15. Haziot, A., B. Tsuberi, and S. M. Goyert. 1993. Neutrophil CD14: biochemical properties and role in the secretion of TNFα in response to LPS. J. Immunol. 150:5556.
16. De Jonge, B. L. M., Y.-S. Chang, D. Gage, and A. Tomasz. 1992. Peptidoglycan composition of a highly methicillin-resistant Staphylococcus aureus strain: the role of penicillin binding protein 2A. J. Biol. Chem. 267:11248.
17. Sheehan, K. C., N. H. Ruddle, and R. D. Schreiber. 1989. Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factors. J. Immunol. 142:3884.
18. Rozalska, B., and T. Wadstrom, 1993. Interferon-γ, interleukin-1 and tumour necrosis factor-α synthesis during experimental murine staphylococcal infection. FEMS Immunol. Med. Microbiol. 7:145.
19. Nakane, A., M. Okamoto, M. Asano, M. Kohanawa, and T. Minagawa. 1995. Endogenous γ interferon, tumor necrosis factor, and interleukin-6 in Staphylococcus aureus infection in mice. Infect. Immun. 63:1165.
20. Bone, R. C. 1993. How Gram-positive organisms cause sepsis. J. Crit. Care 8:51.
21. De Kimpe, S. J., M. Kengatharan, C. Thiemermann, and J. R. Vane. 1995. The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure. Proc. Natl. Acad. Sci. USA 92:10359.
22. Gillaspy, A. F., C. Y. Lee, S. Sau, A. L. Cheung, and M. S. Smeltzer. 1998. Factors affecting the collagen binding capacity of Staphylococcus aureus. Infect. Immun. 66:3170.
23. Wilkinson, B. J., and K. M. Holmes. 1979. Staphylococcus aureus cell surface: capsule as a barrier to bacteriophage adsorption. Infect. Immun. 23:549.
24. Wilkinson, B. J., S. P. Sisson, Y. Kim, and P. K. Peterson. 1979. Localization of the third component of complement on the cell wall of encapsulated Staphylococcus aureus M: implications for the mechanism of resistance to phagocytosis. Infect. Immun. 26:1159.
25. Beutler, B., and A. Cerami. 1986. Cachectin and tumor necrosis factor as two sides of the same biological coin. Nature 320:584.
26. Freudenberg, M. A., and C. Galanos. 1991. Tumor necrosis factor α mediates lethal activity of killed Gram-negative and Gram-positive bacteria in D-galactosamine-treated mice. Infect. Immun. 59:2110.
27. Weidemann, B., J. Schletter, R. Dziarski, S. Kusumoto, F. Stelter, E. T. Rietschel, H. D. Flad, and A. J. Ulmer. 1997. Specific binding of soluble peptidoglycan and muramyldipeptide to CD14 on human monocytes. Infect. Immun. 65:858.
28. Takai, T., M. Ono, M. Hikida, H. Ohmori, and J. V. Ravetch. 1996. Augmented humoral and anaphylactic responses in Fc-γRII-deficient mice. Nature 379:346.
29. Sato, S., A. S. Miller, M. Inaoki, C. B. Bock, P. J. Jansen, M. L. Tang, and T. F. Tedder. 1996. CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. Immunity 5:551.
30. O'Keefe, T., G. T. Williams, S. L. Davies, and M. S. Neuberger. 1996. Hyperresponsive B cells in CD22-deficient mice. Science 274:798.
31. Nishizumi, H., K. Horikawa, I. Mlinaric-Rascan, and T. Yamamoto. 1998. A double-edged kinase Lyn: a positive and negative regulator for antigen receptor-mediated signals. J. Exp. Med. 187:1343.
32. Stefanova, I., M. Corcoran, E. Horak, L. Wahl, J. Bolen, and I. Horak. 1993. Lipopolysaccharide induces activation of CD14-associated protein tyrosine kinase p53/56 Lyn. J. Biol. Chem. 268:20725.