Oligonucleotide aggregates bind to the macrophage scavenger receptor

European Journal of Biochemistry

Volumn 260, Issue 3, 1999, Pages 855-860

  Suzuki, Kazuo ^a   Doi, Takefumi ^b   Imanishi, Takeshi ^b   Kodama, Tatsuhiko ^b   Tanaka, Toshiki ^a  

^a BIOMOL ENG RESEARCH INSTITUTE   (Japan)

^b NONE

Author keywords

Aggregates; Ligand specificity; Macrophage scavenger receptor; Oligonucleotide; Quadruplex

Indexed keywords

OLIGONUCLEOTIDE; SCAVENGER RECEPTOR;

ANIMAL CELL; ARTICLE; CHO CELL; CIRCULAR DICHROISM; LIGAND BINDING; MACROPHAGE; MOLECULAR MODEL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RECEPTOR BINDING; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CATTLE; CHO CELLS; CRICETINAE; LIPOPROTEINS, LDL; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; OLIGORIBONUCLEOTIDES; RECEPTORS, IMMUNOLOGIC; RECEPTORS, SCAVENGER;

EID: 0033559715     PISSN: 00142956     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-1327.1999.00233.x     Document Type: Article

References (31)

1. Goldstein, J.L., Ho, Y.K., Basu, S.K. & Brown, M.S. (1979) Binding site on macrophages that mediates uptake and degradation of acetylated low density lipoprotein, producing massive cholesterol deposition. Proc. Natl Acad. Sci. USA 76, 333-337.
2. Brown, M.S. & Goldstein, J.L. (1983) Lipoprotein metabolism in the macrophage: implications for cholesterol deposition in atherosclerosis. Annu. Rev. Biochem. 52, 223-261.
3. Krieger, M. (1992) Molecular flypaper and atherosclerosis: structure of the macrophage scavenger receptor. Trends Biochem Sci. 17, 141-146.
4. Kodama, T., Freeman, M., Rohrer, L., Zabrecky, J., Matsudaira, P. & Krieger, M. (1990) Type I macrophage scavenger receptor contains α-helical and collagen-like coiled coils. Nature 343, 531-535.
5. Rohrer, L., Freeman, M., Kodama, T., Penman, M. & Krieger, M. (1990) Coiled-coil fibrous domains mediate ligand binding by macrophage scavenger receptor type II. Nature 343, 570-572.
6. Doi, T., Higashino, K., Kurihara, Y., Wada, Y., Miyazaki, T., Nakamura, H., Uesugi, S., Imanishi, T., Kawabe, Y., Itakura, H., Yazaki, Y., Matsumoto, A. & Kodama, T. (1993) Charged collagen structure mediates the recognition of negatively charged macromolecules by macrophage scavenger receptors. J. Biol. Chem. 268, 2126-2133.
7. Acton, S., Resnick, D., Freeman, M., Ekkel, Y., Ashkenas, J. & Krieger, M. (1993) The collagenous domains of macrophage scavenger receptors and complement component Clq mediate their similar, but not identical, binding specificities for polyanionic ligands. J. Biol. Chem. 268, 3530-3537.
8. Kodama, T., Reddy, P., Kishimoto, C. & Krieger, M. (1988) Purification and characterization of a bovine acetyl low density lipoprotein receptor. Proc. Natl Acad. Sci. USA 85, 9238-9242.
9. Mato, M., Ookawara, S., Sakamoto, A., Aikawa, E., Ogawa, T., Mitsuhashi, U., Masuzawa, T., Suzuki, H., Honda, M., Yazaki, Y., Watanabe, E., Luoma, J., Yle-Herttuala, S., Fraser, I., Gordon, S. & Kodama, T. (1996) Involvement of specific macrophage-lineage cells surrounding arterioles in barrier and scavenger function in brain cortex. Proc. Natl Acad. Sci. USA 93, 3269-3274.
10. Mattson, M.K. & Rydel, R.E. (1996) Amyloid ox-tox transducers. Nature 382, 674-675.
11. El Khoury, J., Hickman, S.E., Thomas, C.A., Cao, L., Silverstein, S.C. & Loike, J.D. (1996) Scavenger receptor-mediated adhesion of microglia to β-amyloid fibrils. Nature 382, 716-719.
12. Sawai, K., Mahato, R.I., Oka, Y., Takakura, Y. & Hashida, M. (1996) Disposition of oligonucleotides in isolated perfused rat kidney: involvement of scavenger receptors in their renal uptake. J. Pharmacol. Exp. Ther. 279, 284-290.
13. Bijsterbosch, M.K., Manoharan, M., Rump, E.T., De Vrueh, R.L.A., Van Veghel, R., Tivel, K.L., Biessen, E.A.L., Bennett, F., Cook, P.D. & Van Berkel, T.J.C. (1997) In vivo fate of phosphorothioate antisense oligodeoxynucleotides: predominant uptake by scavenger receptors on endothelial liver cells. Nucleic Acids Res. 25, 3290-3296.
14. Biessen, E.A.L., Vietsch, H., Kuiper, J., Bijsterbosch, M.K. & Van Berkel, T.J.C. (1998) Liver uptake of phosphodiester oligodeoxynucleotides is mediated by scavenger receptors. Mol. Pharmacol. 53, 262-269.
15. Pearson, A.M., Rich, A. & Krieger, M. (1993) Polynucleotide binding to macrophage scavenger receptors depend on the formation of base-quartet-stabilized four-stranded helices. J. Biol. Chem. 268, 3546-3554.
16. Tanaka, T., Nishikawa, A., Tanaka, Y., Nakamura, H., Kodama, T., Imanishi, T. & Doi, T. (1996) Synthetic collagen-like domain derived from the macrophage scavenger receptor binds acetylated low-density lipoprotein in vitro. Protein Eng. 9, 307-313.
17. Yamamoto, K., Nishimura, N., Doi, T., Imanishi, T., Kodama, T., Suzuki, K. & Tanaka, T. (1997) The lysine cluster in the collagen-like domain of the scavenger receptor provides for its ligand binding and ligand specificity. FEBS Lett. 414, 182-186.
18. Sambrook, J., Fritsch, E.F. & Maniatis, T. (1989) In: Molecular Cloning: a Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
19. Goldstein, J.L., Basu, S.K. & Brown, M.S. (1983) Receptor-mediated endocytosis of low-density lipoprotein in cultured cells. Methods Enzymol. 98, 241-260.
20. Williamson, J.R., Raghuraman, M.K. & Cech, T.R. (1989) Monovalent cation-induced structure of telomeric DNA: the G-quartet model. Cell 59, 871-880.
21. 3] G-tetraplex. J. Mol. Biol. 251, 76-94.
22. Shida, T., Yokoyama, K., Tamai, S. & Sekiguchi, J. (1991) Self-association of telomeric short oligodeoxyribonucleotides containing a dG cluster. Chem. Pharm. Bull. 39, 2207-2211.
23. Balagurnmoorthy, P., Brahmachari, S.K., Mohanty, D., Bansal, M. & Sasisekharan, V. (1992) Hairpin and parallel quartet structures for telomeric sequences. Nucleic Acid Res. 20, 4061-4067.
24. Malmgvist, M. (1993) Biospecific interaction analysis using biosensor technology. Nature 361, 186-187.
25. Mielewczyk, S.S., Breslauer, K.J., Anachi, R.B. & Brodsky, B. (1996) Binding studies of a triple-helical peptide model of macrophage scavenger receptor to tetraplex nucleic acids. Biochemistry 35, 11396-11402.
26. 4T. Biochemistry, 31, 2455-2459.
27. Hardin, C.C., Henderson, E., Watson, T. & Prosser, J.K. (1991) Monovalent cation induced structural transitions in telomeric DNAs: G-DNA folding intermediates. Biochemistry, 30, 4460-4472.
28. Wang, Y. & Patel, D.J. (1993) Solution structure of a parallel-stranded G-quadruplex DNA. J. Mol. Biol. 234, 1171-1183.
29. Araki, N., Higashi, T., Mori, T., Shibayama, R., Kawabe, Y., Kodama, T., Takahashi, K., Shichiri, M. & Horiuchi, S. (1995) Macrophage scavenger receptor mediates the endocytic uptake and degradation of advanced glycation end products of the Maillard reaction. Eur. J. Biochem. 230, 408-415.
30. Zhang, H., Yang, Y. & Steinbrecher, U.P. (1993) Structural requirements for the binding of modified proteins to the scavenger receptor of macrophages. J. Biol. Chem. 268, 5535-5542.
31. Lougheed, M. & Steinbrecher, U.P. (1996) Mechanism of uptake of copper-oxidized low density lipoprotein in macrophages is dependent on its extent of oxidation. J. Biol. Chem. 271, 11798-11805.