메뉴 건너뛰기




Volumn 38, Issue 3, 1999, Pages 216-227

Influence of the α1-adrenergic antagonist, doxazosin, on noradrenaline-induced modulation of cytoskeletal proteins in cultured hyperplastic prostatic stromal cells

Author keywords

Doxazosin; Flow cytometry; Human prostate; Noradrenaline; Smooth muscle cells; Stroma; Tissue culture

Indexed keywords

ACTIN; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; CYTOSKELETON PROTEIN; DOXAZOSIN; FLUORESCEIN; MYOSIN; NORADRENALIN; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT;

EID: 0033556706     PISSN: 02704137     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0045(19990215)38:3<216::AID-PROS6>3.0.CO;2-0     Document Type: Article
Times cited : (26)

References (29)
  • 1
    • 0030969734 scopus 로고    scopus 로고
    • Prostatic alphal-adrenoceptors and uroselectivity
    • Andersson KE, Lepor H, Wyllie H, Wyllie M. Prostatic alphal-adrenoceptors and uroselectivity. Prostate 1997;30:202-215.
    • (1997) Prostate , vol.30 , pp. 202-215
    • Andersson, K.E.1    Lepor, H.2    Wyllie, H.3    Wyllie, M.4
  • 2
    • 0018702220 scopus 로고
    • Light microscopic analysis of the normal human prostate and of benign prostatic hyperplasia
    • Bartsch G, Müller HR, Oberholzer M, Rohr HP. Light microscopic analysis of the normal human prostate and of benign prostatic hyperplasia. J Urol 1979;122:487-491.
    • (1979) J Urol , vol.122 , pp. 487-491
    • Bartsch, G.1    Müller, H.R.2    Oberholzer, M.3    Rohr, H.P.4
  • 4
    • 0028577211 scopus 로고
    • Morphometry of the prostate: I. Distribution of tissue components in hyperplastic glands
    • Marks LS, Treiger B, Dorey FJ, Fu YS, de Kernion JB. Morphometry of the prostate: I. Distribution of tissue components in hyperplastic glands. Urology 1994;44:486-492.
    • (1994) Urology , vol.44 , pp. 486-492
    • Marks, L.S.1    Treiger, B.2    Dorey, F.J.3    Fu, Y.S.4    De Kernion, J.B.5
  • 5
    • 0026643758 scopus 로고
    • The relative proportion of stromal and epithelial hyperplasia is related to the development of symptomatic benign prostate hyperplasia
    • Shapiro E, Becich MJ, Hartanto V, Lepor H. The relative proportion of stromal and epithelial hyperplasia is related to the development of symptomatic benign prostate hyperplasia. J Urol 1992;147:1293-1297.
    • (1992) J Urol , vol.147 , pp. 1293-1297
    • Shapiro, E.1    Becich, M.J.2    Hartanto, V.3    Lepor, H.4
  • 6
    • 0028965121 scopus 로고
    • Percentage area density of epithelial and mesenchymal components in benign prostatic hyperplasia: Comparison of results between single biopsy, multiple biopsies and multiple tissue specimens
    • Robert M, Costa P, Bressolle F, Mottet N, Navratil H. Percentage area density of epithelial and mesenchymal components in benign prostatic hyperplasia: comparison of results between single biopsy, multiple biopsies and multiple tissue specimens. Br J Urol 1995;75:317-324.
    • (1995) Br J Urol , vol.75 , pp. 317-324
    • Robert, M.1    Costa, P.2    Bressolle, F.3    Mottet, N.4    Navratil, H.5
  • 7
    • 0026841280 scopus 로고
    • Quantifying the smooth muscle content of the prostate using double-immunoenzymatic staining and color assisted image analysis
    • Shapiro E, Hartanto V, Lepor H. Quantifying the smooth muscle content of the prostate using double-immunoenzymatic staining and color assisted image analysis. J Urol 1992;147:1167-1170.
    • (1992) J Urol , vol.147 , pp. 1167-1170
    • Shapiro, E.1    Hartanto, V.2    Lepor, H.3
  • 10
    • 0029039329 scopus 로고
    • Noradrenaline contractions of human prostate mediated by alpha 1A-(alpha 1c-) adrenoceptor subtype
    • Marshall I, Burt RP, Chapple CR. Noradrenaline contractions of human prostate mediated by alpha 1A-(alpha 1c-) adrenoceptor subtype. Br J Pharmacol 1995;115:781-786.
    • (1995) Br J Pharmacol , vol.115 , pp. 781-786
    • Marshall, I.1    Burt, R.P.2    Chapple, C.R.3
  • 11
    • 0027326003 scopus 로고
    • Identification, quantification, and localization of mRNA for three distinct alpha 1 adrenergic receptor subtypes in human prostate
    • Price DT, Schwinn DA, Lomasney JW, Allen LF, Caron MG, Lefkowitz RJ. Identification, quantification, and localization of mRNA for three distinct alpha 1 adrenergic receptor subtypes in human prostate. J Urol 1993;150:546-551.
    • (1993) J Urol , vol.150 , pp. 546-551
    • Price, D.T.1    Schwinn, D.A.2    Lomasney, J.W.3    Allen, L.F.4    Caron, M.G.5    Lefkowitz, R.J.6
  • 13
    • 0030046158 scopus 로고    scopus 로고
    • Selective alpha 1-adrenoceptor antagonists in benign prostatic hyperplasia: Rationale and clinical experience
    • Chapple CR. Selective alpha 1-adrenoceptor antagonists in benign prostatic hyperplasia: rationale and clinical experience. Eur Urol 1996;29:129-144.
    • (1996) Eur Urol , vol.29 , pp. 129-144
    • Chapple, C.R.1
  • 14
    • 0030109784 scopus 로고    scopus 로고
    • The use of alpha-adrenoceptor antagonists in the pharmacological management of benign prostatic hypertrophy: An overview
    • Hieble JP, Ruffolo RR. The use of alpha-adrenoceptor antagonists in the pharmacological management of benign prostatic hypertrophy: an overview. Pharmacol Res 1996;33:145-160.
    • (1996) Pharmacol Res , vol.33 , pp. 145-160
    • Hieble, J.P.1    Ruffolo, R.R.2
  • 15
    • 0031021415 scopus 로고    scopus 로고
    • Doxazosin for benign prostatic hyperplasia: Long-term efficacy and safety in hypertensive and normotensive patients
    • The Multicenter Study Group
    • Lepor H, Kaplan SA, Klimberg I, Mobley DF, Fawzy A, Gaffney M, Ice K, Dias N. Doxazosin for benign prostatic hyperplasia: long-term efficacy and safety in hypertensive and normotensive patients. The Multicenter Study Group. J Urol 1997;157:525-530.
    • (1997) J Urol , vol.157 , pp. 525-530
    • Lepor, H.1    Kaplan, S.A.2    Klimberg, I.3    Mobley, D.F.4    Fawzy, A.5    Gaffney, M.6    Ice, K.7    Dias, N.8
  • 16
    • 0029935363 scopus 로고    scopus 로고
    • Doxazosin: A new approach to hypertension and benign prostatic hyperplasia
    • Pool JL. Doxazosin: a new approach to hypertension and benign prostatic hyperplasia. Br J Clin Pract 1996;50:154-163.
    • (1996) Br J Clin Pract , vol.50 , pp. 154-163
    • Pool, J.L.1
  • 17
    • 0031949916 scopus 로고    scopus 로고
    • Prostatic stromal cell phenotype is directly modulated by norepinephrine
    • Smith P, Rhodes NP, Beesley C, Ke Y, Foster CS. Prostatic stromal cell phenotype is directly modulated by norepinephrine. Urology 1998;51:663-670.
    • (1998) Urology , vol.51 , pp. 663-670
    • Smith, P.1    Rhodes, N.P.2    Beesley, C.3    Ke, Y.4    Foster, C.S.5
  • 18
    • 0023925702 scopus 로고
    • Application of the MTT assay to human prostate cancer cell lines in vitro: Establishment of test conditions and assessment of hormone-stimulated growth and drug-induced cytostatic and cytotoxic effects
    • Romijn JC, Verkoelen CF, Schroeder FH. Application of the MTT assay to human prostate cancer cell lines in vitro: establishment of test conditions and assessment of hormone-stimulated growth and drug-induced cytostatic and cytotoxic effects. Prostate 1988;12:99-110.
    • (1988) Prostate , vol.12 , pp. 99-110
    • Romijn, J.C.1    Verkoelen, C.F.2    Schroeder, F.H.3
  • 19
    • 0021963924 scopus 로고
    • Smooth muscle phenotypic changes in arterial wall homeostasis: Implications for the pathogenesis of atherosclerosis
    • Campbell GR, Campbell JH. Smooth muscle phenotypic changes in arterial wall homeostasis: implications for the pathogenesis of atherosclerosis. Exp Mol Pathol 1985;42:139-162.
    • (1985) Exp Mol Pathol , vol.42 , pp. 139-162
    • Campbell, G.R.1    Campbell, J.H.2
  • 20
    • 0021967040 scopus 로고
    • Adult human arterial smooth muscle cells in primary culture. Modulation from contractile to synthetic phenotype
    • Thyberg J, Nilsson J, Palmberg L, Sjölund M. Adult human arterial smooth muscle cells in primary culture. Modulation from contractile to synthetic phenotype. Cell Tissue Res 1985;239:69-74.
    • (1985) Cell Tissue Res , vol.239 , pp. 69-74
    • Thyberg, J.1    Nilsson, J.2    Palmberg, L.3    Sjölund, M.4
  • 21
    • 0026570307 scopus 로고
    • Receptor function studies in specimens from proximal human urethra obtained by transurethral resection
    • Amark P, Kinn AC, Nergardh A. Receptor function studies in specimens from proximal human urethra obtained by transurethral resection. Urol Res 1992;20:55-58.
    • (1992) Urol Res , vol.20 , pp. 55-58
    • Amark, P.1    Kinn, A.C.2    Nergardh, A.3
  • 22
    • 0028176385 scopus 로고
    • Alpha 1-adrenoceptors and calcium sources in adrenergic neurogenic contractions of rat vas deferens
    • Bultmann R, Kurz AK, Starke K. Alpha 1-adrenoceptors and calcium sources in adrenergic neurogenic contractions of rat vas deferens. Br J Pharmacol 1994;111:151-158.
    • (1994) Br J Pharmacol , vol.111 , pp. 151-158
    • Bultmann, R.1    Kurz, A.K.2    Starke, K.3
  • 23
    • 0030000076 scopus 로고    scopus 로고
    • Inhibition by tamsulosin of tension responses of human hyperplastic prostate to electrical field stimulation
    • Chueh SC, Guh JH, Chen J, Lai MK, Ko FN, Teng CM. Inhibition by tamsulosin of tension responses of human hyperplastic prostate to electrical field stimulation. Eur J Pharmacol 1996;305:177-180.
    • (1996) Eur J Pharmacol , vol.305 , pp. 177-180
    • Chueh, S.C.1    Guh, J.H.2    Chen, J.3    Lai, M.K.4    Ko, F.N.5    Teng, C.M.6
  • 24
    • 0028135058 scopus 로고
    • Pharmacological evidence of distinct alpha 1-adrenoceptor subtypes mediating contraction of human prostatic urethra and peripheral artery
    • Hatano A, Takahashi H, Tamaki M, Komeyama T, Koizumi T, Takeda M. Pharmacological evidence of distinct alpha 1-adrenoceptor subtypes mediating contraction of human prostatic urethra and peripheral artery. Br J Pharmacol 1994;113:723-728.
    • (1994) Br J Pharmacol , vol.113 , pp. 723-728
    • Hatano, A.1    Takahashi, H.2    Tamaki, M.3    Komeyama, T.4    Koizumi, T.5    Takeda, M.6
  • 25
    • 0029779304 scopus 로고    scopus 로고
    • Evaluation of the pharmacological selectivity profile of alpha 1-adrenoceptor antagonists at prostatic alpha 1-adrenoceptors: Binding, functional and in vivo studies
    • Kenny BA, Miller AM, Williamson IJ, O'Connell J, Chalmers DH, Naylor AM. Evaluation of the pharmacological selectivity profile of alpha 1-adrenoceptor antagonists at prostatic alpha 1-adrenoceptors: binding, functional and in vivo studies. Br J Pharmacol 1996;118:871-878.
    • (1996) Br J Pharmacol , vol.118 , pp. 871-878
    • Kenny, B.A.1    Miller, A.M.2    Williamson, I.J.3    O'Connell, J.4    Chalmers, D.H.5    Naylor, A.M.6
  • 26
    • 0028170803 scopus 로고
    • Functional identification of alpha 1-adrenoceptor subtypes in human prostate: Comparison with those in rat vas deferens and spleen
    • Teng CM, Guh JH, Ko FN. Functional identification of alpha 1-adrenoceptor subtypes in human prostate: comparison with those in rat vas deferens and spleen. Eur J Pharmacol 1994;265: 61-66.
    • (1994) Eur J Pharmacol , vol.265 , pp. 61-66
    • Teng, C.M.1    Guh, J.H.2    Ko, F.N.3
  • 27
    • 0026806060 scopus 로고
    • A possible role of decreased relaxation mediated by beta-adrenoceptors in bladder outlet obstruction by benign prostatic hyperplasia
    • Tsujii T, Azuma H, Yamaguchi T, Oshima H. A possible role of decreased relaxation mediated by beta-adrenoceptors in bladder outlet obstruction by benign prostatic hyperplasia. Br J Pharmacol 1992;107:803-807.
    • (1992) Br J Pharmacol , vol.107 , pp. 803-807
    • Tsujii, T.1    Azuma, H.2    Yamaguchi, T.3    Oshima, H.4
  • 29
    • 0023275185 scopus 로고
    • Activated Ki-ras oncogene in human prostatic adenocarcinoma
    • Peehl DM, Wehner N, Stamey TA. Activated Ki-ras oncogene in human prostatic adenocarcinoma. Prostate 1987;10:281-289.
    • (1987) Prostate , vol.10 , pp. 281-289
    • Peehl, D.M.1    Wehner, N.2    Stamey, T.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.