Age-dependent changes in rat liver microsomal membrane structure and functions under benzene treatment

Mechanisms of Ageing and Development

Volumn 106, Issue 3, 1999, Pages 273-282

  Sukhodub, Andrey L ^a,c   Padalko, Vladimir I ^b  

^a Res Inst Dermatol and Venerology   (Ukraine)

^b V N KARAZIN KHARKIV NATIONAL UNIVERSITY   (Ukraine)

^c NONE   (Ukraine)

Author keywords

Age; Benzene; Cytochrome P 450; Glucose dehydrogenase; Glucose 6 phosphatase; Metabolism; Microsomal membrane

Indexed keywords

BENZENE; CYTOCHROME P450; DEOXYCHOLIC ACID; GLUCOSE 6 PHOSPHATASE; GLUCOSE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; XENOBIOTIC AGENT;

ADOLESCENT; AGE; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HYDROXYLATION; LIVER MICROSOME; MALE; MEMBRANE STRUCTURE; MEMBRANE VESICLE; MICROSOME MEMBRANE; NONHUMAN; PRIORITY JOURNAL; RAT;

AGING; ANIMALS; BENZENE; CYTOCHROME P-450 ENZYME SYSTEM; FOLLOW-UP STUDIES; GLUCOSE 1-DEHYDROGENASE; GLUCOSE DEHYDROGENASES; GLUCOSE-6-PHOSPHATASE; MALE; MEMBRANES; MICROSOMES, LIVER; RATS; RATS, WISTAR; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

ANIMALIA;

EID: 0033556039     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0047-6374(98)00120-1     Document Type: Article

References (34)

1. Arinc, E., Adali, O., Iscan, M., Guray, T., 1991. Stimulatory effects of benzene on rabbit liver and kidney microsomal cytochrome P-450 dependent drug metabolism enzymes. Arch. Toxicol. 65, 186-190.
2. Armbrecht, H., Birnbaum, L., Zenser, T.V., Davis, B.B., 1982. Changes in hepatic microsomal membrane fluidity with age. Exp. Gerontol. 17, 41-48.
3. Bublitz, C., Steavenson, S., 1988. The use of glucose dehydrogenase to monitor the integrity of microsomes. Biochem. Biophys. Acta 965 (C131), 90-92.
4. Buege, J.-A., Aust, S.-D., 1978. Microsomal lipid peroxidation. Methods Enzymol. 52C, 302-310.
5. Chen, J.J., Yu, B.P., 1994. Alterations in mitochondrial membrane fluidity by lipid peroxidation products. Free Radic. Biol. Med. 17, 411-418.
6. Dallner, G., 1963. Studies on the structural and enzymic organisation of the membranes elements of liver microsomes. Acta Pathol. Microbiol. Scand. (Suppl.) 166, 94.
7. Denk, H., 1979. Effects of detergents on the mixed function oxidase and other microsomal enzymes. Pharmacol. Ther. 6, 551-577.
8. Engelke, M., Bergmann, U., Diehl, H.A., 1993. Fluidity of the microsomal membrane and cytochrome P-450 reduction kinetics of pig liver microsomes as a consequence of organic solvent impact. Xenobiotica 23, 71-78.
9. Gervasi, P.G., Puccini, P., Longo, V., Lippi, A., 1991. Role of acetone inducible P-450IIE1 in the deethylation of diethylnitrosamine in hamster, Biol. React. Intermed. IV: Mol. Cell Eff. Impact Hum. Health. 4th Int. Symp., Tuscon, AZ, January 14-17, 1990, pp. 285-287.
10. Gut, I., Nedelcheva, V., Soucek, P., Stopka, P., Tichavska, B., 1996. Cytochromes P450 in benzene metabolism and involvement of their metabolites and reactive oxygen species in toxicity. Environ. Health Perspect. 104 (Suppl. 6), 1211-1218.
11. Imai, Y., Ito, A., Sato, R., 1966. Evidence for biochemically different types of vesicles in the hepatic microsomal fraction. J. Biochem. 60, 417-428.
12. 2+ with endoplasmic reticulum of rat liver: a standard procedure for the isolation of rat liver microsomes. Anal. Biochem. 48, 53-61.
13. Karuzina, I.I., Archakov, A.I., 1994. Hydrogen peroxide-mediated inactivation of microsomal cytochrome P-450 during monooxygenase reactions. Free Radic. Biol. Med. 17, 557-567.
14. Klinger, W., 1996. Biotransformation of drugs and other xenobiotics during postnatal development. Exp. Toxicol. Pathol. 48 (1), 1-88.
15. Lakowicz, J.R., 1983. Principles of Fluorescence Spectroscopy. Plenum Press. New York.
16. Lemeshko, V.V., 1983. Age peculiarities of the interaction between fluorescent probes and thyroxine with the membranes of rat liver microsomes. Biofizika 28, 985-989.
17. Miller, G.I., 1959. Protein determination for large numbers of samples. Anal. Chem. 31, 964-966.
18. Nash, T., 1953. Colorimetric estimation of formaldehyde by means of the Hantzsch reaction. Biochem. J. 55, 416-421.
19. Nelson, D.H., Ruhmann-Wenhold, A., 1979. Effect of lipid extraction, adrenalectomy and cortisol upon free radical formation by rat lung microsomes. J. Steroid Biochem. 11, 1381-1384.
20. O'Mahony, M.S., Woodhouse, K.W., 1994. Age, environmental factors and drug metabolism. Pharmacol. Ther. 61, 279-287.
21. Omura, T., Sato, R., 1964. The carbon monoxide binding pigment of liver microsomes. II. Solubilization, purification and properties. J. Biol. Chem. 239, 2379-2385.
22. Parke, D.V., 1996. Personal reflections on 50 years study of benzene toxicology. Environ. Health Perspect. 104 (Suppl. 6), 1123-1128.
23. Plewka, A., Plewka, D., Kaminski, M., 1993. Age associated differences in effects of benzene on mixed-function oxidases in phenobarbital-treated rats. Polish J. Occup. Med. Environ. Health 6, 43-53.
24. Rikans, L.E., 1989. Influence of aging on chemically induced hepatotoxicity: role of age-related changes in metabolism. Drug Metab. Rev. 20, 87-110.
25. Romanelli, A., Stdenis, J.F., Vidal, H., Tschu, S., Van de Werve, G., 1994. Absence of glucose uptake by liver microsomes: an explanation for the complete latency of glucose dehydrogenase. Biochem. Biophys. Res. Commun. 200, 1491-1497.
26. Rutten, A.A.J.J.L., Falke, H.E., Catsburg, J.F., Topp, R., Bleauboer, B.J., Van Holsteijn, I., Doorn, L., Leeuwen, F.X., Van, R.O., 1987. Interlaboratory comparison of total cytochrome P-450 and protein determinations in rat liver microsomes. Reinvestigation of assay conditions. Arch. Toxicol. 61, 27-33.
27. Schmucker, D.H., Wang, R.K., 1981. Effects of aging and phenobarbital on the rat liver microsomal drug-metabolizing system. Mech. Ageing Dev. 15, 189-202.
28. Schmucker, D.H., Vessey, D.A., Wang, R.K., James, J.L., Maloney, A., 1984. Age-dependent alterations in the physico-chemical properties of rat liver microsomes. Mech. Ageing Dev. 27, 207-217.
29. Snyder, R., Hedli, C.C., 1996. An overview of benzene metabolism. Environ. Health Perspect. 104, 1165-1171.
30. Soucek, P., Filipova, B., Gut, I., 1994. Cytochrome P-450 destruction and radical scavenging by benzene and its metabolites: evidence for the key role of quinones. Biochem. Pharmacol. 47, 2233-2242.
31. Sukhodub, A.L., 1997. Activity of microsomal liver enzymes and blood serum glucose level in normal and benzene-treated rats of different age. Ukr. Biochim. Zh. 69, 119-121.
32. Waddel, I.D., Burchell, A., 1991. Transverse topology of glucose-6-phosphatase in rat hepatic endoplasmic reticulum. Biochem. J. 275, 133-137.
33. Waxman, D.J., Morrissey, J.J., LeBlanc, G.A., 1989. Female-predominant rat hepatic P-450 forms j (IIE1) and 3 (IIA1) are under hormonal regulatory controls distinct from those of the sex-specific P-450 forms. Endocrinology 124 (6), 2954-2966.
34. Zhang, Z., Goldstein, B.D., Witz, G., 1995. Iron-stimulated ring-opening of benzene in a mouse liver microsomal system. Mechanistic studies and formation of a new metabolite. Biochem. Pharmacol. 50, 1607-1617.