Lack of protection from ischemic injury of monoamine oxidase B-deficient mice following middle cerebral artery occlusion

Neuroscience Letters

Volumn 259, Issue 3, 1999, Pages 161-164

  Holschneider, D P ^a,b   Scremin, O U ^b,c   Huynh, L ^c   Chen, K ^d   Shih, J C ^a,d  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Focal cerebral ischemia; L Deprenyl; Monoamine oxidase B; Neuroprotection

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; SELEGILINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; BRAIN PROTECTION; CAUTERIZATION; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; ENZYME DEFICIENCY; INTRAPERITONEAL DRUG ADMINISTRATION; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

EID: 0033555584     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(98)00819-2     Document Type: Article

References (19)

1. Ansari K.S., Yu P.H., Kruck T.P., Tatton W.G. Rescue of axotomized immature rat facial motoneurons by R(-)-deprenyl: stereospecificity and independence from monoamine oxidase inhibition. J. Neurosci. 13:1993;4042-4053.
2. Ballabriga J., Pellise A., Ferrer I. L-Deprenyl does not reduce brain damage in global forebrain ischemia in adult gerbils (Meriones ungiculatus). J. Neurol. Sci. 148:1997;1-5.
3. Barone F.C., Price W.J., White R.F., Willette R.N., Feuerstein G.Z. Genetic hypertension and increased susceptibility to cerebral ischemia. Neurosci. Biobehav. Rev. 16:1992;219-233.
4. Bederson J.B., Pitts L.H., Tsuji M., Nishimura M.C., Davis R.L., Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke. 17:1986;472-476.
5. Damsma G., Boisvert D.P., Mudrick L.A., Wenkstern D., Fibiger H.C. Effects of transient forebrain ischemia and pargyline on extracellular concentrations of dopamine, serotonin, and their metabolites in the rat striatum as determined by in vivo microdialysis. J. Neurochem. 54:1990;801-808.
6. Fujii M., Hara H., Meng W., Vonsattel J.P., Huang Z., Moskowitz M.A. Strain-related differences in susceptibility to transient forebrain ischemia in SV-129 and C57black/6 mice. Stroke. 28:1997;1805-1810.
7. Grimsby J., Toth M., Karoum F., Klaidman L., Adams J., Chen K., Shih J.C. Increased stress response and p-phenylethylamine in MAOB-deficient mice. Nat. Genet. 17:1997;206-210.
8. Kitani K., Miyasaka K., Kanai S., Carrillo M.C., Ivy G.O. Upregulation of antioxidant enzyme activities by deprenyl. Implications for life span extension. Ann. N.Y. Acad. Sci. 786:1996;391-409.
9. Knollema S., Aukema W., Hom H., Korf J., ter Horst G.J. L-Deprenyl reduces brain damage in rats exposed to transient hypoxia-ischemia. Stroke. 26:1995;1883-1887.
10. Lahtinen H., Koistinaho J., Kauppinen R., Haapalinna A., Keinanen R., Sivenius J. Selegiline treatment after transient global ischemia in gerbils enhances the survival of CA1 pyramidal cells in the hippocampus. Brain Res. 757:1997;260-267.
11. Matsui Y., Kumagae Y. Monoamine oxidase inhibitors prevent striatal neuronal necrosis induced by transient forebrain ischemia. Neurosci. Lett. 126:1991;175-178.
12. McCulloch J., Harper A.M. Factors influencing the response of the cerebral circulation to phenylethylamine. Neurology. 29:1979;201-207.
13. Paterson I.A., Barber A.J., Gelowitz D.L., Voll C. (-)Deprenyl reduces delayed neuronal death of hippocampal pyramidal cells. Neurosci. Biobehav. Rev. 21:1997;181-186.
14. Sandler M., Youdim M.B., Hanington E. A phenylethylamine oxidising defect in migraine. Nature. 250:1974;335-337.
15. Scremin, O.U., Holschneider, D.P., Chen, K., Li, M.G. and Shih, J.C., Effects of phenylethylamine on cerebral cortical blood flow of mice lacking the monoamine oxidase B gene, 27th Annual Meeting of the Society for Neuroscience, 1997, abstract 614.19.
16. Scremin O.U., Li M.G., Scremin A.M., Jenden D.J. Cholinesterase inhibition improves blood flow in the ischemic cerebral cortex. Brain Res. Bull. 42:1997;59-70.
17. Semkova I., Wolz P., Schilling M., Krieglstein J. Selegiline enhances NGF synthesis and protects central nervous system neurons from excitotoxic and ischemic damage. Eur. J. Pharmacol. 315:1996;19-30.
18. Simonson S.G., Zhang J., Canada A.T. Jr., Su Y.F., Benveniste H., Piantadosi C.A. Hydrogen peroxide production by monoamine oxidase during ischemia-reperfusion in the rat brain. J. Cereb. Blood Flow Metab. 13:1993;125-134.
19. Weinachter S.N., Blavet N., O'Donnell R.A., MacKenzie E.T., Rapin J.R. Models of hypoxia and cerebral ischemia. Pharmacopsychiatry. 23(Suppl. 2):1990;94-97.