Effects of ivermectin and midecamycin on ryanodine receptors and the Ca2+-ATPase in sarcoplasmic reticulum of rabbit and rat skeletal muscle

Journal of Physiology

Volumn 514, Issue 2, 1999, Pages 313-326

  Ahern, Gerard P ^a   Junankar, Pauline R ^a   Pace, Suzy M ^a   Curtis, Suzanne ^a   Mould, Jorgen A ^a   Dulhunty, Angela F ^a  

^a Biology and Environment   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM MAGNESIUM); ADENOSINE TRIPHOSPHATASE (CALCIUM); CAFFEINE; CALCIUM ION; FK 506 BINDING PROTEIN; IVERMECTIN; LACTONE DERIVATIVE; MIDECAMYCIN; RUTHENIUM RED; RYANODINE RECEPTOR; THAPSIGARGIN;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; EXTENSOR DIGITORUM LONGUS MUSCLE; IMMUNOBLOTTING; LIPID BILAYER; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT; SARCOPLASMIC RETICULUM; SKELETAL MUSCLE; ADULT; ANIMAL CELL; BINDING SITE; CALCIUM CONDUCTANCE; ENZYME ACTIVITY; EXTRACELLULAR CALCIUM; MALE; MUSCLE FIBER CONTRACTION; NEW ZEALAND WHITE (RABBIT); PROTEIN BINDING;

ANIMALS; CA(2+) MG(2+)-ATPASE; CAFFEINE; CALCIUM; CALCIUM-TRANSPORTING ATPASES; IMMUNOPHILINS; IVERMECTIN; LEUCOMYCINS; LIPID BILAYERS; MACROLIDES; MUSCLE CONTRACTION; MUSCLE, SKELETAL; RABBITS; RATS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM; SIROLIMUS; TACROLIMUS BINDING PROTEINS; THAPSIGARGIN;

EID: 0033555470     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1999.313ae.x     Document Type: Article

References (49)

1. AHERN, G. P., JUNANKAR, P. R. & DULHUNTY, A. F. (1994). Single channel activity of the ryanodine receptor calcium release channel is modulated by FK506. FEBS Letters 352, 369-374.
2. AHERN, G. P., JUNANKAR, P. R. & DULHUNTY, A. F. (1997a). Subconductance states in single-channel activity of skeletal muscle ryanodine receptors after removal of FKBP12. Biophysical Journal 72, 146-162.
3. AHERN, G. P., JUNANKAR, P. R. & DULHUNTY, A. F. (1997b). Ryanodine receptors from rabbit skeletal muscle are reversibly activated by rapamycin. Neuroscience Letters 225, 81-84.
4. ARENA, J. P., LIU, K. K., PARESS, P. S., FRAZIER, E. G., CULLY, D. F., MROZIK, H. & SCHAEFFER, J. M. (1995). The mechanism of action of avermectins in Caenorhabditis elegans: correlation between activation of glutamate-sensitive chloride current, membrane binding, and biological activity. Journal of Parasitology 81, 286-294.
5. BLOOMQUIST, J. R. (1993). Toxicology, mode of action and target site-mediated resistance to insecticides acting on chloride channels. Comparitive Biochemistry and Physiology C 106, 301-314.
6. BRILLANTES, A.-M. B., ONDRIAS, K., SCOTT, A., KOBRINSKY, E., ONDRIASOVA, E., MOSCHELLA, M. C., JAYARAMAN, T., LANDERS, M., EHRLICH, B. E. & MARKS, A. R. (1994). Stabilization of calcium release channel (ryanodine receptor) function by FK506-binding protein. Cell 77, 513-523.
7. BROWNLEE, D. J. A., HOLDEN-DYE, L. & WALKER, R. J. (1997). Actions of the antihelminthic invermectin on the pharyngeal muscle of the parasitic nematode, Ascaris suum. Journal of Parasitology 115, 553-561.
8. CAMPBELL, W. C. (1989). Ivermectin and Abamectin. Springer-Verlag, New York.
9. CHU, A., DIXON, M. C., SAITO, A., SEILER, S. & FLEISCHER, S. (1989). Isolation of sarcoplasmic reticulum fractions referable to longitudinal tubules and junctional terminal cisternae from rabbit skeletal muscle. Methods in Enzymology 157, 36-50.
10. DENT, J. A., DAVIS, M. W. & AVERY, L. (1997). avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans. EMBO Journal 16, 5867-5879.
11. DUCE, I. R., BHANDAL, N. S., SCOTT, R. H. & NORRIS, T. M. (1995). Effects of Ivermectin on gamma-aminobutyric acid- and glutamategated chloride conductance in arthropod skeletal muscle. In Molecular Action of Insecticides on Ion Channels, ed. MARSHALL CLARK, J., pp. 251-263. American Chemical Society, Washington, DC.
12. DULHUNTY, A. F. (1991). Activation and inactivation of excitation-contraction coupling in rat soleus muscle. Journal of Physiology 439, 605-626.
13. DULHUNTY, A. F. (1992). The voltage-activation of contraction in skeletal muscle. Progress in Biophysics and Molecular Biology 57, 181-223.
14. 2+-release channels from sheep myocardium. American Journal of Physiology 272, 1908-1919.
15. EL-HAYEK, R., ANTONIU, B., WANG, J., HAMILTON, S. L. & IKEMOTO, N. (1995). Identification of calcium release-triggering and blocking regions of the II-III loop of the skeletal muscle dihydropyridine receptor. Journal of Biological Chemistry 270, 22116-22118.
16. GEARY, T. G., SIMS, S. M., THOMAS, E. M., VANOVER, L., DAVIS, J. P., WINTERROWD, C. A., KLEIN, R. D., HO, N. F. H. & THOMPSON, D. P. (1998). Haemonchus contortus: ivermectin-induced paralysis of the pharynx. Experimental Parasitology 77, 88-96.
17. GOLD, B. G., ZELENY-POOLEY, M., WANG, M. S., CHATURVEDI, P. & ARMISTEAD, D. M. (1997). A nonimmunosuppressant FKBP-12 ligand increases nerve regeneration. Experimental Neurology 147, 269-278.
18. HAMILTON-MILLER, J. M. T. (1992). In-vitro activities of 14-, 15- and 16-membered macrolides against Gram-positive cocci. Journal of Antimicrobial Chemotherapy 29, 141-147.
19. HARDING, M. W., GALAT, A., UEHLING, D. E. & SCHREIBER, S. L. (1989). A receptor for the immunosuppressant FK506 is a cis-trans peptidyl-prolylsomerase. Nature 341, 758-761.
20. HOPKINS, K. D., MARCELLA, K. L. & STRECKER, A. E. (1990). Ivermectin toxicosis in a dog. American Veterinary Medical Association Journal 197, 93-94.
21. 1a binds to high- and low-affinity sites with dual effects on the gamma-aminobutyric acidgated chloride channel of cultured cerebellar granule neurons. Journal of Pharmacology and Experimental Therapeutics 281, 261-266.
22. JAYARAMAN, T., BRILLANTES, A.-M., TIMERMAN, A. P., FLEISCHER, S., ERDJUMENT-BROMAGE, H., TEMPST, P. & MARKS, A. R. (1992). FK506 binding protein associated with the calcium release channel (ryanodine receptor). Journal of Biological Chemistry 267, 9474-9477.
23. KOURIE, J. I., LAVER, D. R., JUNANKAR, P. R., GAGE, P. W. & DULHUNTY, A. F. (1996). Characteristics of two types of chloride channel in sarcoplasmic reticulum vesicles of rabbit skeletal muscle. Biophysical Journal 70, 202-221.
24. LAMB, G. D. & STEPHENSON, D. G. (1990). Calcium release in skinned muscle fibres of the toad by transverse tubule depolarization or by direct stimulation. Journal of Physiology 423, 495-517.
25. LAVER, D. R., BAYNES, T. M. & DULHUNTY, A. F. (1997). Magnesium inhibition of ryanodine receptor calcium channels: evidence for two independent mechanisms. Journal of Membrane Biology 156, 213-229.
26. 2+ inhibits the ryanodine receptor from cardiac muscle. Journal of Membrane Biology 147, 7-22.
27. LOVELL, R. A. (1990). Ivermectin and piperazine toxicoses in dogs and cats. Veterinary Clinics of North America Small Animal Practice 20, 453-468.
28. LU, X., XU, L. & MEISSNER, G. (1994). Activation of the skeletal muscle calcium release channel by a cytoplasmic loop of the dihydropyridine receptor. Journal of Biological Chemistry 269, 6511-6516.
29. MA, J., FILL, M., KNUDSON, C. M., CAMPBELL, K. P. & CORONADO, R. (1988). Ryanodine receptor of skeletal muscle is a gap junction-type channel. Science 242, 99-102.
30. MACK, M. M., MOLINSKI, T. F., BUCK, E. D. & PESSAH, I. N. (1994). Novel modulators of skeletal muscle FKBP12/calcium channel complex from Ianthella basta. Journal of Biological Chemistry 269, 23236-23249.
31. MANEV, H., FAVARON, M., CANDEO, P., FADDA, E., LIPARTITI, M. & MILANI, D. (1993). Macrolide antibiotics protect neurons in culture against the N-methyl-D-aspartate (NMDA) receptor-mediated toxicity of glutamate. Brain Research 624, 331-335.
32. MARKS, P. W. & MAXFIELD, F. R. (1991). Preparation of solutions with free Ca concentration in the nanomolar range using 1,2-bis(o-aminophenoxy)ethane-N,N,N′,N′-tetracetic acid. Annals of Biochemistry 193, 61-71.
33. MAYRLEITNER, M., TIMERMAN, A. P., WIEDERRECHT, G. & FLEISCHER, S. (1994). The calcium release channel of sarcoplasmic reticulum is modulated by FK-506 binding protein: effect of FKBP-12 on single channel activity of the skeletal muscle ryanodine receptor. Cell Calcium 15, 99-108.
34. MAZZEI, T., MINI, E., NOVELLI, A. & PERITI, P. (1993). Chemistry and mode of action of macrolides. Journal of Antimicrobial Chemotherapy 31, 1-9.
35. 2+ release channels and their regulation by endogenous effectors. Annual Review of Physiology 56, 485-508.
36. 2+-release channel activation in skeletal muscle sarcoplasmic reticulum. American Journal of Physiology 272, C622-627.
37. 1, a 60-membered macrolide from skeletal muscle sarcoplasmic reticulum. Biochimica et Biophysica Acta 1294, 177-182.
38. OHTA, T., ENDO, M., NAKANO, T., MOROHOSHI, Y., WANIKAWA, K. & OHGA, A. (1989). Ca-induced Ca release in malignant hyperthermia-susceptible pig skeletal muscle. American Journal of Physiology 256, C358-367.
39. 3H1 cells. American Journal of Physiology 272, C601-614.
40. 2+, caffeine, and adenine nucleotides. Molecular Pharmacology 31, 232-238.
41. ROHRER, S. P. & ARENA, J. P. (1995). Ivermectin interactions with invertebrate ion channels. In Molecular Action of Insecticides on Ion Channels, ed. MARSHALL CLARK, J., pp. 264-283. American Chemical Society, Washington, DC.
42. 2+ transport ATPase by thapsigargin at subnanomolar concentrations. Journal of Biological Chemistry 266, 13503-13506.
43. SAITO, A., SEILER, S., CHU, A. & FLEISCHER, S. (1984). Preparation and morphology of sarcoplasmic reticulum terminal cisternae from rabbit skeletal muscle. Journal of Cell Biology 99, 875-885.
44. SMITH, J. S., IMAGAWA, T., MA, J., FILL, M., CAMPBELL, K. P. & CORONADO, R. (1988). Purified ryanodine receptor from rabbit skeletal muscle is the calcium-release channel of sarcoplasmic reticulum. Journal of General Physiology 92, 1-26.
45. STEINER, J. P., CONNOLLY, M. A., VALENTINE, H. L., HAMILTON, G.S., DAWSON, T. M., HESTER, L. & SNYDER, S. H. (1997a). Neurotrophic actions of nonimmunosuppressive analogues of immunosuppressive drugs FK506, rapamycin and cyclosporin A. Nature Medicine 3, 421-428.
46. STEINER, J. P., HAMILTON, G. S., ROSS, D. T., VALENTINE, H. L., GUO, H., CONNOLLY, M. A., LIANG, S., RAMSEY, C., LI, J. H. & HUANG, W. (1997b). Neurotrophic immunophilin ligands stimulate structural and functional recovery in neurodegenerative animal models. Proceedings of the National Academy of Sciences of the USA 94, 2019-2024.
47. TIMERMAN, A. P., OGUNBUMNI, E., FREUND, E., WIEDERRECHT, G., MARKS, A. R. & FLEISCHER, S. (1993). The calcium release channel of sarcoplasmic reticulum is modulated by FK-506-binding protein. Journal of Biological Chemistry 268, 22992-22999.
48. WAGENKNECHT, T., GRASSUCCI, R., BERKOWITZ, J., WIEDERRECHT, G. J., XIN, H.-B. & FLEISCHER, S. (1996). Cryoelectron microscopy resolves FK506-binding protein sites on the skeletal muscle ryanodine receptor. Biophysical Journal 70, 1709-1715.
49. i in intact single fibres from mouse muscle. Journal of Physiology 466, 611-628.