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Asymmetry in the allylic substrate adjacent to the π-allyl complex has only been investigated in the context of intramolecular cyclizations or intermolecular reactions with cyclic substrates. For recent examples, see a) J. Pohlmann, C. Sabater, H. M. R. Hoffmann, Angew. Chem. 1998, 110, 656; Angew. Chem. Int. Ed. 1998, 37, 633;
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Recently an example of an adjacent stereocenter influencing the stereoselective formation of a π-allyl palladium complex was reported: V. Atlan, S. Racouchot, M. Rubin, C. Bremer, J. Ollivier, A. de Meijere, J. Salaün, Tetrahedron: Asymmetry 1998, 9, 1131.
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6] followed by a Mitsunobu reaction with phthalimide afforded a diamine derviative which correlated spectroscopically to the minor isomer 8b.
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