Transcription factors of the Sp1 family: Interaction with E2F and regulation of the murine thymidine kinase promoter

Journal of Molecular Biology

Volumn 293, Issue 5, 1999, Pages 1005-1015

  Rotheneder, Hans ^a   Geymayer, Sibylle ^a   Haidweger, Eva ^a  

^a NONE

Author keywords

E2F; Protein protein interaction; Sp1; Thymidine kinase; Transcription factor

Indexed keywords

CYCLIN A; OLIGONUCLEOTIDE; THYMIDINE KINASE; TRANSCRIPTION FACTOR E2F; TRANSCRIPTION FACTOR SP1;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FIBROBLAST; IMMUNOPRECIPITATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; REPORTER GENE;

ANIMALIA; DROSOPHILA MELANOGASTER; MELANOGASTER; MURINAE;

EID: 0033550316     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.1999.3213     Document Type: Article

References (41)

1. Adams P. D., Kaelin W. G. Jr. The cellular effects of E2F overexpression. Curr. Top. Microbiol. Immunol. 208:1996;79-93.
2. Bandara L. R., Buck V. M., Zamanian M., Johnston L. H., La Thangue N. B. Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F. EMBO J. 12:1993;4317-4324.
3. Birnbaum M. J., van Wijnen A. J., Odgren P. R., Last T. J., Suske G., Stein G. S., Stein J. L. Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3. Biochemistry. 34:1995;16503-16508.
4. Cobrinik D., Whyte P., Peeper D. S., Jacks T., Weinberg R. A. Cell cycle-specific association of E2F with the p130 E1A-binding protein. Genes Dev. 7:1993;2392-2404.
5. De Luca P., Majello B., Lania L. Sp3 represses transcription when tethered to promoter DNA or targeted to promoter proximal RNA. J. Biol. Chem. 271:1996;8533-8536.
6. Doetzlhofer A., Rotheneder H., Lagger G., Koranda M., Kurtev V., Brosch G., Wintersberger E., Seiser C. Histone deacetylase 1 can repress transcription by binding to Sp1. Mol. Cell. Biol. 19:1999;5504-5511.
7. Dynlacht B. D., Brook A., Dembski M., Yenush L., Dyson N. DNA-binding and trans-activation properties of Drosophila E2F and DP proteins. Proc. Natl Acad. Sci. USA. 91:1994;6359-6363.
8. Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev. 12:1998;2245-2262.
9. Gregory R. C., Taxman D. J., Seshasayee D., Kensinger M. H., Bieker J. J., Wojchowski D. M. Functional interaction of GATA1 with erythroid Kruppel-like factor and Sp1 at defined erythroid promoters. Blood. 87:1996;1793-1801.
10. Hagen G., Muller S., Beato M., Suske G. Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucl. Acids Res. 20:1992;5519-5525.
11. Hagen G., Muller S., Beato M., Suske G. Sp1-mediated transcriptional activation is repressed by Sp3. EMBO J. 13:1994;3843-3851.
12. Han I., Kudlow J. E. Reduced O glycosylation of Sp1 is associated with increased proteasome susceptibility. Mol. Cell. Biol. 17:1997;2550-2558.
13. Hateboer G., Wobst A., Petersen B. O., Le Cam L., Vigo E., Sardet C., Helin K. Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F. Mol. Cell. Biol. 18:1998;6679-6697.
14. Helin K., Wu C. L., Fattaey A. R., Lees J. A., Dynlacht B. D., Ngwu C., Harlow E. Heterodimerization of the transcription factors E2F-1 and DP-1 leads to cooperative trans-activation. Genes Dev. 7:1993;1850-1861.
15. Imataka H., Sogawa K., Yasumoto K., Kikuchi Y., Sasano K., Kobayashi A., Hayami M., Fujii Kuriyama Y. Two regulatory proteins that bind to the basic transcription element (BTE), a GC box sequence in the promoter region of the rat P-4501A1 gene. EMBO. J. 11:1992;3663-3671.
16. Jordan K. L., Haas A. R., Logan T. J., Hall D. J. Detailed analysis of the basic domain of the E2F1 transcription factor indicates that it is unique among bHLH proteins. Oncogene. 9:1994;1177-1185.
17. Karlseder J., Rotheneder H., Wintersberger E. Interaction of Sp1 with the growth- and cell cycle-regulated transcription factor E2F. Mol. Cell. Biol. 16:1996;1659-1667.
18. Kennett S. B., Udvadia A. J., Horowitz J. M. Sp3 encodes multiple proteins that differ in their capacity to stimulate or repress transcription. Nucl. Acids Res. 25:1997;3110-3117.
19. Kingsley C., Winoto A. Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression. Mol. Cell. Biol. 12:1992;4251-4261.
20. Krek W., Ewen M. E., Shirodkar S., Arany Z., Kaelin W. G. Jr, Livingston D. M. Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell. 78:1994;161-172.
21. Lam E. W., La Thangue N. B. DP and E2F proteins: coordinating transcription with cell cycle progression. Curr. Opin. Cell Biol. 6:1994;859-866.
22. Lee J. S., Galvin K. M., Shi Y. Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1. Proc. Natl Acad. Sci. USA. 90:1993;6145-6149.
23. Lin S. Y., Black A. R., Kostic D., Pajovic S., Hoover C. N., Azizkhan J. C. Cell cycle-regulated association of E2F1 and Sp1 is related to their functional interaction. Mol. Cell. Biol. 16:1996;1668-1675.
24. Majello B., De Luca P., Lania L. Sp3 is a bifunctional transcription regulator with modular independent activation and repression domains. J. Biol. Chem. 272:1997;4021-4026.
25. Merika M., Orkin S. H. Functional synergy and physical interactions of the erythroid transcription factor GATA-1 with the Kruppel family proteins Sp1 and EKLF. Mol. Cell. Biol. 15:1995;2437-2447.
26. Mikulits W., Knofler M., Stiegler P., Dolznig H., Wintersberger E., Mullner E. W. Mouse thymidine kinase stability in vivo and after in vitro translation. Biochim. Biophys. Acta. 1338:1997;267-274.
27. Ogris E., Rotheneder H., Mudrak I., Pichler A., Wintersberger E. A binding site for transcription factor E2F is a target for trans activation of murine thymidine kinase by polyomavirus large T antigen and plays an important role in growth regulation of the gene. J. Virol. 67:1993;1765-1771.
28. Pagano M., Draetta G., Jansen Durr P. Association of cdk2 kinase with the transcription factor E2F during S phase. Science. 255:1992;1144-1147.
29. Pascal E., Tjian R. Different activation domains of Sp1 govern formation of multimers and mediate transcriptional synergism. Genes Dev. 5:1991;1646-1656.
30. Porter W., Saville B., Hoivik D., Safe S. Functional synergy between the transcription factor Sp1 and the estrogen receptor. Mol. Endocrinol. 11:1997;1569-1580.
31. Schneider I. Cell lines derived from late embryonic stages of Drosophila melanogaster. J. Embryol. Exp. Morphol. 27:1972;353-365.
32. Seto E., Lewis B., Shenk T. Interaction between transcription factors Sp1 and YY1. Nature. 365:1993;462-464.
33. Slansky J. E., Farnham P. J. Introduction to the E2F family: protein structure and gene regulation. Curr. Top. Microbiol. Immunol. 208:1996;1-30.
34. Sogawa K., Imataka H., Yamasaki Y., Kusume H., Abe H., Fujii Kuriyama Y. cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2. Nucl. Acids Res. 21:1993;1527-1532.
35. Supp D. M., Witte D. P., Branford W. W., Smith E. P., Potter S. S. Sp4, a member of the Sp1-family of zinc finger transcription factors, is required for normal murine growth, viability, and male fertility. Dev. Biol. 176:1996;284-299.
36. Vallian S., Chin K. V., Chang K. S. The promyelocytic leukemia protein interacts with Sp1 and inhibits its transactivation of the epidermal growth factor receptor promoter. Mol. Cell. Biol. 18:1998;7147-7156.
37. Wells J., Held P., Illenye S., Heintz N. H. Protein-DNA interactions at the major and minor promoters of the divergently transcribed dhfr and rep3 genes during the Chinese hamster ovary cell cycle. Mol. Cell. Biol. 16:1996;634-347.
38. Wu C. L., Zukerberg L. R., Ngwu C., Harlow E., Lees J. A. In vivo association of E2F and DP family proteins. Mol. Cell. Biol. 15:1995;2536-2546.
39. Xu M., Sheppard K. A., Peng C. Y., Yee A. S., Piwnica Worms H. Cyclin A/CDK2 binds directly to E2F-1 and inhibits the DNA-binding activity of E2F-1/DP-1 by phosphorylation. Mol. Cell. Biol. 14:1994;8420-8431.
40. Yokono M., Saegusa N., Matsushita K., Sugiura Y. Unique DNA binding mode of the N-terminal zinc finger of transcription factor Sp1. Biochemistry. 37:1998;6824-6832.
41. Zwicker J., Liu N., Engeland K., Lucibello F. C., Muller R. Cell cycle regulation of E2F site occupation in vivo. Science. 271:1996;1595-1597.