Total synthesis of sanglifehrin A

Angewandte Chemie - International Edition

Volumn 38, Issue 16, 1999, Pages 2447-2451

  Nicolaou, K C ^a,b   Xu, Jinyou ^a,b   Murphy, Fiona ^a,b   Barluenga, Sofia ^a,b   Baudoin, Olivier ^a,b   Wei, Heng Xu ^a,b   Gray, David L F ^a,b   Ohshima, Takashi ^a,b  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Immunosuppressive agents; Natural products; Stille couplings; Total synthesis

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; SANGLIFEHRIN A; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL BOND; CRYSTAL STRUCTURE; DRUG ACTIVITY; DRUG BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERISM; OXIDATION; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0033549745     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1521-3773(19990816)38:16<2447::AID-ANIE2447>3.0.CO;2-O     Document Type: Article

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31. t = 24.0 (1), 36.0 min (37).
32. We thank Dr. Rainer Metternich of Novartis for a sample of natural sanglifehrin A.