Oral cyclosporine decreases severity of neurotoxicity in liver transplant recipients

Neurology

Volumn 52, Issue 8, 1999, Pages 1708-1710

  Wijdicks, Eelco P M ^a   Dahlke, Linda J ^a   Wiesner, Russell H ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN A;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONFUSION; DRUG ABSORPTION; DRUG FORMULATION; FEMALE; HEADACHE; HUMAN; LIVER TRANSPLANTATION; MALE; NEUROTOXICITY; PARESTHESIA; PRIORITY JOURNAL; SEIZURE; TREMOR;

EID: 0033549075     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.52.8.1708     Document Type: Article

References (8)

1. Metha MU, Venkataramanan R, Burckart GJ. Effect of bile on cyclosporine absorption in liver transplant patients. Br J Clin Pharmacol 1988;25:579-582.
2. Holt DW, Johnston A. Cyclosporine microemulsion. A guide to usage and monitoring. Biodrugs 1997;7:175-197.
3. Wijdicks EFM, Wiesner RH, Krom RAF. Neurotoxicity in liver transplant recipients with cyclosporine immunosuppression. Neurology 1995;45:1962-1964.
4. Graziadei IW, Wiesner RH, Marotta PJ, et al. Neoral compared to sandimmune is associated with a decrease in histologie severity of rejection in patients undergoing primary liver transplantation. Transplantation 1997;64:726-731.
5. Min DI, Ku YM, Perry PJ, et al. Effect of grapefruit juice on cyclosporine pharmacokinetics in renal transplant patients. Transplantation 1996;62:123-125.
6. Begley DJ, Squires LK, Zlokovic BV, et al. Permeability of the blood-brain barrier to the immunosuppressive cyclic peptide cyclosporine A. J Neurochem 1990;55:1222-1225.
7. Textor SC, Taler, SJ, Canzanello VJ, et al. Cyclosporine, blood pressure, and atherosclerosis. Cardiol Rev 1997;5:141-151.
8. McDonald JW, Goldberg MP, Gwag BJ, et al. Cyclosporin induces neuronal apoptosis and selective oligodendrocyte death in cortical cultures. Ann Neurol 1996;40:750-758.