From sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylates

Tetrahedron Letters

Volumn 40, Issue 11, 1999, Pages 2195-2198

  Long, Daniel D ^a   Hungerford, Natasha L ^a   Smith, Martin D ^a   Brittain, Dominic E A ^a   Marquess, Daniel G ^b,c   Claridge, Timothy D W ^a   Fleet, George W J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

^c Advanced Medicine Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETAL; CARBOHYDRATE; MONOMER; PEPTIDE DERIVATIVE; POLYMER; TETRAHYDROFURAN DERIVATIVE; TETRAMER;

ARTICLE; CHROMATOGRAPHY; CIS TRANS ISOMERISM; OLIGOMERIZATION; PROTEIN FOLDING; PROTEIN PURIFICATION; STEREOISOMERISM; SYNTHESIS;

EID: 0033548690     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)00110-0     Document Type: Article

References (9)

1. Gellmann, S. H., Acc. Chem. Res., 1998, 31, 173.
2. Smith, M. D., Long, D. D., Martin, A., Marquess, D. G., Claridge, T. D. W., Fleet, G. W. J., Tetrahedron Lett., 1999, 40, 2191 and references cited therein.
3. Claridge, T. D. W., Long, D. D., Hungerford, N. L., Smith, M. D., Aplin, R. T., Marquess, D. G., Fleet, G. W. J., Tetrahedron Lett., 1999, 40, 2199.
4. Long, D.D., Stetz, R.J.E., Nash, R.J., Marquess, D.G., Lloyd, J.D., Winters, A.L., Asano, N., Fleet, G.W.J., submitted for publication.
5. 3 as a solvent.
6. The yields of 2 and 5 are based on the using the weight of the mixture of methyl esters 12 and 14.
7. Bichard, C. J. F., Fairbanks, A. J., Fleet, G. W. J., Ramsden, N. G., Vogt, K., Doherly, O., Pearce, L., Watkin, D. J., Tetrahedron: Asymm., 1991, 2, 901.
8. Fairbanks, A. J., Fleet, G. W. J., Tetrahedron, 1995, 51, 3881.
9. Support from EPSRC and GlaxoWellcome is acknowledged.