Vascular endothelial growth factor expression in peripheral nerves and dorsal root ganglia in diabetic neuropathy in rats

Neuroscience Letters

Volumn 262, Issue 3, 1999, Pages 159-162

  Samii, Amir ^a   Unger, Jürgen ^a   Lange, Winfried ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

Diabetic neuropathy; Dorsal root ganglia; Peripheral nerves; Regeneration; Vascular endothelial growth factor

Indexed keywords

INSULIN ZINC SUSPENSION; MONOCLONAL ANTIBODY; RECOMBINANT NERVE GROWTH FACTOR; STREPTOZOCIN; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC NEUROPATHY; HYPERGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MALE; NERVE FIBER REGENERATION; NONHUMAN; PERIKARYON; PERIPHERAL NERVE; PRIORITY JOURNAL; RAT; SCHWANN CELL; SCIATIC NERVE; SENSORY NEUROPATHY; SPINAL GANGLION; STREPTOZOCIN DIABETES; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; BRAIN NEOPLASMS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEUROPATHIES; ENDOTHELIAL GROWTH FACTORS; ENDOTHELIUM, VASCULAR; GANGLIA, SPINAL; GENE EXPRESSION REGULATION; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; INSULIN; LYMPHOKINES; MALE; NERVE FIBERS; NERVE GROWTH FACTORS; NERVE REGENERATION; NEURONS; RATS; RATS, INBRED LEW; RECOMBINANT PROTEINS; REFERENCE VALUES; SCIATIC NERVE; STROMAL CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 0033548514     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00064-6     Document Type: Article

References (20)

1. Alheim K., McDowell T.L., Symons J.A., Duff G.W., Bartfai T. An AP-1 site is involved in the NGF induction of IL-1 alpha in PC12 cells. Neurochem. Int. 29:1996;487-496.
2. Apfel S.C., Arezzo J.C., Brownlee M., Federoff H., Kessler J.A. Nerve growth factor administration protects against experimental diabetic sensory neuropathy. Brain Res. 634:1994;7-12.
3. Bartholdi D., Rubin B.P., Schwab M.E. VEGF mRNA induction correlates with changes in the vasculature upon spinal cord damage in the rat. Eur. J. Neurosci. 9:1997;2549-2560.
4. Beck L., D'Amore P.A. Vascular development: cellular and molecular regulation. FASEB J. 11:1997;365-373.
5. Cameron N.E., Cotter M.A., Low P.A. Nerve blood flow in early experimental diabetes in rats: relation to conduction deficits. Am. J. Physiol. 261:1991;E1-E8.
6. Carmeliet P., Ferreira V., Breier G., Pollefeyt S., Kieckens L., Gertsenstein M., Fahrig M., Vandenhoeck A., Harpal K., Eberhardt C. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature. 380:1996;435-439.
7. Creange A., Barlovatz Meimon G., Gherardi R.K. Cytokines and peripheral nerve disorders. Eur. Cytokine Netw. 8:1997;145-151.
8. Dyck P.J., Giannini C. Pathologic alterations in the diabetic neuropathies of humans: a review. J. Neuropathol. Exp. Neurol. 55:1996;1181-1193.
9. Fujimoto E., Mizoguchi A., Hanada K., Yajima M., Ide C. Basic fibroblast growth factor promotes extension of regenerating axons of peripheral nerve. In vivo experiments using a Schwann cell basal lamina tube model. J. Neurocytol. 26:1997;511-528.
10. Hammes H.P., Lin J., Bretzel R.G., Brownlee M., Breier G. Upregulation of the vascular endothelial growth factor/vascular endothelial growth factor receptor system in experimental background diabetic retinopathy of the rat. Diabetes. 47:1998;401-406.
11. Hobson M.I., Brown R., Green C.J., Terenghi G. Inter-relationships between angiogenesis and nerve regeneration: a histochemical study. Br. J. Plast. Surg. 50:1997;125-131.
12. Ikeda E., Achen M.G., Breier G., Risau W. Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells. J. Biol. Chem. 270:1995;19761-19766.
13. Klagsbrun M., D'Amore P.A. Vascular endothelial growth factor and its receptors. Cytokine Growth Factor Rev. 7:1996;259-270.
14. Kremer C., Breier G., Risau W., Plate K.H. Up-regulation of flk-1/vascular endothelial growth factor receptor 2 by its ligand in a cerebral slice sulture system. Cancer Res. 57:1997;3852-3859.
15. Plate K.H., Breier G., Weich H.A., Risau W. Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature. 359:1992;845-848.
16. Schütz G., Schröder J.M. Number and size of epineural blood vessels in normal and diseased human sural nerves. Cell Tiss. Res. 290:1997;31-37.
17. Shweiki D., Itin A., Neufeld G., Gitay Goren H., Keshet E. Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis. J. Clin. Invest. 91:1993;2235-2243.
18. Toews A.D., Hostettler J., Barrett C., Morell P. Alterations in gene expression associated with primary demyelination and remyelination in the peripheral nervous system. Neurochem. Res. 22:1997;1271-1280.
19. Unger J.W., Klitzsch T., Pera S., Reiter R. Nerve Growth Factor (NGF) and diabetic neuropathy in the rat: morphological investigations of the sural nerve, dorsal root ganglion, and spinal cord. Exp. Neurol. 152:1998;1-12.
20. Zhang Z., Guth L. Experimental spinal cord injury: Wallerian degeneration in the dorsal column is followed by revascularization, glial proliferation, and nerve regeneration. Exp. Neurol. 147:1997;159-171.