Structural basis for the differential toxicity of cholera toxin and Escherichia coli heat-labile enterotoxin: Construction of hybrid toxins identifies the A2-domain as the determinant of differential toxicity

Journal of Biological Chemistry

Volumn 274, Issue 7, 1999, Pages 3962-3969

  Rodighiero, Chiara ^a   Aman, Abu T ^a   Kenny, Martin J ^a   Moss, Joel ^b   Lencer, Wayne I ^c   Hirst, Timothy R ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN; ESCHERICHIA COLI ENTEROTOXIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; NONHUMAN; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION; TOXIN ANALYSIS;

AMINO ACID SEQUENCE; BACTERIAL TOXINS; CELL LINE; CHOLERA TOXIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENTEROTOXINS; ESCHERICHIA COLI PROTEINS; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; POLYMERASE CHAIN REACTION;

ANIMALIA; ESCHERICHIA COLI;

EID: 0033548246     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.7.3962     Document Type: Article

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