Suicide gene therapy for treatment of retinoblastoma in a murine model

Human Gene Therapy

Volumn 10, Issue 3, 1999, Pages 441-448

  Hurwitz, Mary Y ^a   Marcus, Karen T ^a   Chévez Barrios, Patricia ^a   Louie, Kathryn ^a,b   Aguilar Cordova, Estuardo ^a,b   Hurwitz, Richard L ^a,b  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b CENTER FOR CELL AND GENE THERAPY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GANCICLOVIR; PRODRUG; THYMIDINE KINASE; VIRUS VECTOR;

ADENOVIRUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE THERAPY; GENETIC TRANSDUCTION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; INTRAOCULAR DRUG ADMINISTRATION; MOUSE; NONHUMAN; RETINOBLASTOMA; SUICIDE GENE; VIRUS GENE;

ADENOVIRIDAE; ANIMALS; EYE NEOPLASMS; GANCICLOVIR; GENE THERAPY; HELA CELLS; HERPES SIMPLEX; HUMANS; MICE; MICE, KNOCKOUT; NEOPLASM TRANSPLANTATION; PRODRUGS; RETINOBLASTOMA; THYMIDINE KINASE; TRANSDUCTION, GENETIC; TUMOR CELLS, CULTURED;

ADENOVIRIDAE; ANIMALIA; HERPES; MURINAE; SIMPLEXVIRUS;

EID: 0033540660     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/10430349950018887     Document Type: Article

References (40)

1. ABRAMSON, D.H. (1990). Retinoblastoma incidence in the United States. Arch. Ophthalmol. 108, 1514.
2. ABRAMSON, D.H., ELLSWORTH, R.M., and KITCHIN, F.D. (1984). Second nonocular tumors in retinoblastoma survivors: Are they radiation induced? Ophthalmology 99, 1351-1355.
3. ALVAREZ, R.D., and CURIEL, D.T. (1997). A phase I study of recombinant adenovirus vector-mediated intraperitoneal delivery of herpes simplex virus thymidine kinase (HSV-TK) gene and intravenous ganciclovir for previously treated ovarian and extraovarian cancer patients. Hum. Gene Ther. 8, 597-613.
4. BARBA, D., HARBIN, J., SADELAIN, M., and GAGE, F.H. (1994). Development of anti-tumor immunity following thymidine kinase-mediated killing of experimental brain tumors. Proc. Natl. Acad. Sci. U.S.A. 91, 4348-4352.
5. BEHBAKHT, K., BENJAMIN, I., CHIU, H.C., ECK, S.L., VAN DEERLIN, P.C., RUBIN, S.C., and BOYD, J. (1996). Adenovirus-mediated gene therapy of ovarian cancer in a mouse model. Am. J. Obstet. Gynecol. 175, 1260-1265.
6. BENNETT, J., WILSON, J., SUN, D., FORBES, B., and MAGUIRE, A. (1994). Adenovirus vector-mediated in vivo gene transfer into adult murine retina. Invest. Ophthalmol. Vis. Sci. 35, 2535-2542.
7. BONNEKOH, B., GREENHALGH, D.A., BUNDMAN, D.S., ECKHARDT, J.N., LONGLEY, M.A., CHEN, S.-H., WOO, S.L.C., and ROOP, D.R. (1995). Inhibition of melanoma growth by adenoviral-mediated HSV thymidine kinase gene transfer in vivo. J. Invest. Dermatol. 104, 313-317.
8. BRYNE, J., FEARS, T.R., WHITNEY, C., and PARRY, D.M. (1995). Survival after retinoblastoma: Long-term consequences and family history of cancer. Med. Pediatr. Oncol. 24, 160-165.
9. CAVENEE, W.K., DRYJA, T.P., PHILLIPS, R.A., BENEDICT, W.F., GODBOUT, R., GALLIE, B.L., MURPHREE, A.L., STRONG, L.C., and WHITE, R.L. (1983). Expression of recessive alleles by chromosomal mechanisms of retinoblastoma. Nature (London) 305, 779-784.
10. CHEN, S.-H., SHINE, H.D., GOODMAN, J.C., GROSSMAN, R.G., and WOO, S.L.C. (1994). Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc. Natl. Acad. Sci. U.S.A. 91, 3054-3057.
11. CHEN, S.-H., CHEN, X.H.L., WANG, Y., KOSAI, K.-I., FINEGOLD, M.J., RICH, S.S., and WOO, S.L.C. (1995). Combination gene therapy for liver metastasis of colon carcinoma in vivo. Proc. Natl. Acad. Sci. U.S.A. 92, 2577-2581.
12. CHEVÉZ-BARRIOS, P., HURWITZ, M.Y., LOUIE, K., MARCUS, K.T., AGUILAR-CORDOVA, C.E., and HURWITZ, R.L. (1998). Retinoblastoma: Models of tumor progression. Invest. Ophthalmol. Vis. Sci. 39, S815.
13. CULVER, K.W. (1995). Somatic cell gene therapy: 1990-1994. Int. Pediatr. 10, 10-21.
14. DONALDSON, S.S., EGBERT, P.R., NEWSHAM, I., and CAVENEE, W.K. (1997). Retinoblastoma. In Principles and Practice of Pediatric Oncology. P.A. Pizzo and D.G. Poplack, eds. (Lippincott-Raven, Philadelphia) pp. 699-715.
15. DRAPER, G.J., SANDERS, B.M., and KINGSTON, J.E. (1986). Second primary neoplasms in patients with retinoblastoma. Br. J. Cancer 53, 661-671.
16. DRYJA, T.P., CAVENEE, W.K., WHITE, R.L., RAPAPORT, J.M., PETERSEN, R., ALBERT, D.M., and BRUNS, G.A. (1984). Homozygosity of chromosome 13 in retinoblastoma. N Engl. J. Med. 310, 550-553.
17. EASTHAM, J.A., CHEN, S-H., SEHGAL, I., YANG, G., TIMME, T.L., HALL, S.J., WOO, S.L.C., and THOMPSON, T.C. (1996). Prostate cancer gene therapy: Herpes simplex virus thymidine kinase gene transduction followed by ganciclovir in mouse and human prostate cancer models. Hum. Gene Ther. 7, 515-523.
18. ESANDI, M.C., VAN SOMEREN, G.D., VINCENT, A.J., VAN BEKKUM, D.W., VALERIO, D., BOUT, A., and NOTEBOOM, J.L. (1997). Gene therapy of experimental malignant mesothelioma using adenovirus vectors encoding the HSVtk gene. Gene Ther. 4, 280-287.
19. FRANCKE, V., and KUNG, F. (1976). Sporadic bilateral retinoblastoma in 13q-chromosomal deletion. Med. Pediatr. Oncol. 2, 379-385.
20. FREEMAN, S., ABBOUD, C., WHARTENBY, K., PACKMAN, C., KOEPLIN, D., MOOLTEN, F., and ABRAHAM, G. (1993). The "bystander effect": Tumor regression when a fraction of the tumor mass is genetically modified. Cancer Res 53, 5274-5283.
21. GALLIE, B.L., BUDNING, A., DEBOER, G., THIESSEN, J.J., KOREN, G., VERJEE, Z., LING, V., and CHAN, H.S. (1996). Chemotherapy with focal therapy can cure intraocular retinoblastoma without radiotherapy. Arch. Ophthalmol. 114(11), 1321-1328.
22. GOEBEL, E.A., DAVIDSON, B.L., ZABNER, J., GRAHAM, S.M., and KERN, J.A. (1996). Adenovirus-mediated gene therapy for head and neck squamous cell carcinomas. Ann. Otol. Rhinol. Laryngol. 105, 562-567.
23. HOROWITZ, J.M., PARK, S.H., BOGENMANN, E., CHENG, J.C., YANDELL, D.W., KAYE, F.J., MINNA, J.D., DRYJA, T.P., and WEINBERG, R.A. (1990). Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells. Proc. Natl. Acad. Sci. U.S.A. 87, 2775-2779.
24. HOROWITZ, M.S. (1990). Adenoviridae and their replication. In Virology. 2nd ed. B.N. Fields, D.M. Knipe, et al., eds. (Raven Press, New York) pp. 1679-1721.
25. KAY, M.A., and WOO, S.L.C. (1994). Gene therapy for metabolic disorders. Trends Genet. 10, 253-257.
26. KNUDSON, A.G., JR., MEADOWS, A.T., NICHOLS, W.W., and HILL, R. (1976). Chromosomal deletion and retinoblastoma. N. Engl. J. Med. 295, 1120-1123.
27. LEE, W.-H., BOOKSTEIN, R., HONG, F., YOUNG, L.J., SHEW, J.Y., and LEE, E.-H. (1987). Human retinoblastoma susceptibility gene: Cloning, identification, and sequence. Science 235, 1394-1399.
28. LI, T., ADAMIAN, M., ROOF, D.J., BERSON, E.L., DRYJA, T.P., ROESSLER, B.J., and DAVIDSON, B.L. (1994). In vivo transfer of a reporter gene to the retina mediated by an adenoviral vector. Invest. Ophthalmol. Vis. Sci. 35, 2543-2549.
29. LUEDER, G.T., and GOYAL, R. (1996). Visual function after laser hyperthermia and chemotherapy for macular retinoblastoma. Am. J. Ophthalmol. 121, 582-584.
30. MARTIN, D.F., PARKS, D.J., MELLOW, S.D., FERRIS, F.L., WALTON, R.C., REMALEY, N.A., CHEW, E.Y., ASHTON, P., DAVIS, M.D., and NUSSENBLATT, R.B. (1994). Treatment of cytomegalovirus retinitis with an intraocular sustained-release ganciclovir implant: A randomized controlled clinical trial. Arch. Ophthalmol. 112(12), 1531-1539.
31. MURPHREE, A.L., VILLABLANCA, J.G., DEEGAN, W.F., III, SATO, J.K., MALOGOLOWKIN, M., FISHER, A., PARKER, R., REED, E., and GOMER, C.J. (1996). Chemotherapy plus local treatment in the management of intraocular retinoblastoma. Arch. Ophthalmol. 114, 1348-1356.
32. NYBERG-HOFFMAN, C., SHABRAM, P., LI, W., GIROUX, D., and AGUILAR-CORDOVA, C.E. (1997). Sensitivity and reproducibility in adenoviral infectious titer determination. Nature Med. 3, 808-811.
33. O'MALLEY, B.W., JR., CHEN, S.-H., SCHWARTZ, M.R., and WOO, S.L.C. (1995). Adenovirus-mediated gene therapy for human head and neck squamous cell cancer in a nude mouse model. Cancer Res. 55, 1080-1085.
34. PEREZ-CRUET, M.J., TRASK, T.W., CHEN, S.-H., GOODMAN, J.C., WOO, S.L.C., GROSSMAN, R.G., and SHINE, H.D. (1994). Adenovirus-mediated gene therapy of experimental gliomas. J. Neurosci. Res. 39, 506-511.
35. ROARTY, J.D., McLEAN, I.W., and ZIMMERMAN, L.E. (1988). Incidence of second neoplasms in patients with bilateral retinoblastoma Ophthalmology 95, 1583.
36. ROSENFELD, M.E., WANG, M., SIEGAL, G.P., ALVAREZ, R.D., MIKHEEVA, G., KRASNYKH, V., and CURIEL, D.T. (1996). Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma. J. Mol. Med. 74, 455-462.
37. SHIELDS, J.A. (1994). The expanding role of laser photocoagulation for intraocular tumors. 1993 H. Christian Zweng Memorial Lecture. Retina 14, 310-322.
38. SHIELDS, J.A., PARSONS, H., SHIELDS, C.L., and GIBLIN, M.E. (1989). The role of cryotherapy in the management of retinoblastoma. Am. J. Ophthalmol. 108, 260-264.
39. SHINKAI, Y., RATHBUN, G., LAM, K.P., OLTZ, E.M., STEWART, V., MENDELSOHN, M., CHARRON, J., DATTA, M., YOUNG, F., and STALL, A.M. (1992). RAG-2 deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 68, 855-867.
40. TAMBOLI, A., PODGOR, M.J., and HORM, J.W. (1990). The incidence of retinoblastoma in the United States. Arch. Ophthalmol. 108, 128-132.