Association of glutamine 27 polymorphism of β2 adrenoceptor with reported childhood asthma: Population based study

BMJ

Volumn 316, Issue 7132, 1998, Pages 664-

  Hopes, E ^a   Mcdougall, C ^a   Christie, G ^a   Dewar, J ^b   Wheatley, A ^b   Hall, I P ^b   Helms, P J ^b  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b QUEEN S MEDICAL CENTRE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; GLUTAMINE; IMMUNOGLOBULIN E;

ADOLESCENT; ARTICLE; ASTHMA; BRONCHUS REACTIVITY; CHILD; CHILDHOOD DISEASE; CHROMOSOME 5Q; GENETIC POLYMORPHISM; HELPER CELL; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION;

ADOLESCENT; ASTHMA; CHILD; CHILD, PRESCHOOL; GLUTAMINE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; POLYMORPHISM, GENETIC; PREVALENCE; RECEPTORS, ADRENERGIC, BETA-2; SCOTLAND;

EID: 0345333093     PISSN: 09598138     EISSN: 14685833     Source Type: Journal    
DOI: 10.1136/bmj.316.7132.664     Document Type: Article

References (5)

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2. Green SA, Turki J, Bejarano P, Hall I, Liggett SB. Influence of adrenergic receptor genotype on signal transduction in human airway smooth muscle cells. Am J Respir Cell Mol Biol 1995; 13: 25-33.
3. Dewar JC, Wilkinson J, Wheatley A, Thomas NS, Doulle I, Morton N, et al. The glutamine 27 adrenoceptor polymorphism is associated with elevated IgE levels in asthmatic families. J Allergy Clin Immunol 1997; 100: 261-265.
4. 22 polymorphism with lower airway reactivity in asthmatic subjects. Lancet 1995; 345: 1213.
5. Omran M, Russell G. Continuing increase in respiratory symptoms and atopy in Aberdeen schoolchildren. BMJ 1996; 312: 34.