The effect of the Saccharomyces cerevisiae endo-exonuclease NUD1 gene expression on the resistance of HeLa cells to DNA-damaging agents

Mutation Research - DNA Repair

Volumn 433, Issue 3, 1999, Pages 169-181

  Semionov, Alexandre ^a   Cournoyer, Denis ^a   Chow, Terry Y K ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

DNA repair; Endo exonuclease; Homologous recombination; NUD1

Indexed keywords

CHLORAMBUCIL; CHLORMETHINE; CISPLATIN; MESYLIC ACID ETHYL ESTER; NUCLEASE;

ARTICLE; CELL LINE; CELL SURVIVAL; CONTROLLED STUDY; DISEASE RESISTANCE; DNA DAMAGE; DNA REPAIR; DNA TRANSFECTION; ENZYME ACTIVITY; GENE EXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; NORTHERN BLOTTING; PLASMID; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; ULTRAVIOLET IRRADIATION;

ALKYLATING AGENTS; CELL SURVIVAL; CHLORAMBUCIL; CISPLATIN; DEOXYRIBONUCLEASES; DNA DAMAGE; GENE EXPRESSION; GENES, FUNGAL; HELA CELLS; HUMANS; MECHLORETHAMINE; RECOMBINATION, GENETIC; RNA; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSFECTION; ULTRAVIOLET RAYS;

EID: 0033538093     PISSN: 09218777     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0921-8777(99)00002-6     Document Type: Article

References (49)

1. Sancar A. Structure and function of DNA photolyase. Biochemistry. 33:1994;2-9.
2. Samson L. The suicidal DNA repair methyltransferases of microbes. Mol. Microbiol. 6:1992;825-831.
3. Mitra S., Kaina B. Regulation of repair of alkylation damage in mammalian genomes. Prog. Nucleic Acids Res. Mol. Biol. 44:1993;109-142.
4. Sancar A. Mechanisms of DNA excision repair. Science. 266:1994;1954-1956. Review.
5. B. Singer, D. Grunberg, Molecular Biology of Mutagens and Carcinogens, Plenum, New York, 1983.
6. Resnick M.A. The repair of double-strand breaks in DNA: a model involving recombination. J. Theor. Biol. 59:1976;97-106.
7. Resnick M.A., Martin P. The repair of double-strand breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic control. Mol. Gen. Genet. 143:1976;119-129.
8. Fishman-Lobell J., Rudin N., Haber J.E. Two alternative pathways of double-strand break repair that are kinetically separable and independently modulated. Mol. Cell. Biol. 12:1992;1292-1303.
9. Moore J.K., Haber J.E. Cell cycle and genetic requirement of two pathways of nonhomologous end-joining repair of double-strand breaks in Saccharomyces cerevisiae. Mol. Cell. Biol. 16:1996;2144-2173.
10. Sharples G.J., Leach D.R. Structural and functional similarities between the SbcCD proteins of Escherichia coli and the RAD50 and MRE11 (RAD32) recombination and repair proteins of yeast. Mol. Microbiol. 17:1995;1215-1217.
11. Sugawara N., Haber J.E. Characterization of double-strand break-induced recombination: homology requirements and single-stranded DNA formation. Mol. Cell. Biol. 12:1992;563-575.
12. Prakash S., Sung P., Prakash L. DNA repair genes and proteins of Saccharomyces cerevisiae. Annu. Rev. Genet. 27:1993;33-70.
13. Jessberger R., Podust V., Hubscher U., Berg P. A mammalian protein complex that repairs double-strand breaks and deletions by recombination. J. Biol. Chem. 268:1993;15070-15079.
14. Osman F., Subramani S. Double-strand break-induced recombination in eukaryotes [Review]. Prog. Nucleic Acids Res. Mol. Biol. 58:1998;263-299.
15. Holliday R. A mechanism for gene conversion in fungi. Genet. Res. 5:1964;282-304.
16. Meselson M., Radding C.M. A general model for genetic recombination. Proc. Natl. Acad. Sci. USA. 72:1975;358-361.
17. Szostak J.W., Orr-Weaver T.L., Rothstein R.J., Stahl F.W. The double-strand-break repair model for recombination. Cell. 33:1983;25-35.
18. Rosenberg S.M., Hastings P.J. The split-end model for homologous recombination at double-strand breaks and at Chi. Biochimie. 73:1991;385-397.
19. Stahl F. Meiotic recombination in yeast: coronation of the double-strand-break repair model. Cell. 87:1996;965-968. Minireview.
20. Haber J.E., Ray B.L., Kolb J.M., White C.I. Rapid kinetics of mismatch repair of heteroduplex DNA that is formed during recombination in yeast. Proc. Natl. Acad. Sci. USA. 90:1993;3363-3367.
21. Kowalczykowski S.C., Dixon D.A., Eggleston A.K., Lauder S.D., Rehrauer W.M. Biochemistry of homologous recombination in Escherichia coli. Microbiol. Rev. 58:1994;401-465. Review.
22. M.J. Fraser, Endo-exonucleases: actions in the life and death of cells, R.G. Landes, Austin, TX, USA, 1996.
23. T.Y.-K. Chow, M.A. Resnick, The identification of a deoxyribonuclease controled by the RAD52 gene of Saccharomyces cerevisiae, in: E.C. Friedberg, B.A. Bridges (Eds.), Cellular Responses to DNA damage, Alan R. Liss, New York, 1983, pp. 447-455.
24. Chow T.Y.-K., Perkins E.L., Resnick M.A. Yeast RNC1 encodes a chimeric protein, RhoNUC, with a human rho motif and deoxyribonuclease activity. Nucleic Acids Res. 20:1992;39-44.
25. Vincent R.D., Hofmann T.J., Zassenhaus H.P. Sequence and expression of NUC-1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res. 16:1988;3297-3312.
26. Chow T.Y.-K., Resnick M.A. Purification and characterization of an endo-exonuclease activity of yeast that requires a functional RAD52 gene. J. Biol. Chem. 262:1987;17659-17667.
27. Chow T.Y.-K., Fraser M.J. Purification and properties of single-strand DNA-binding endo-exonuclease in Neurospora crassa. J. Biol. Chem. 258:1983;12010-12018.
28. Koa H., Fraser M.J., Kafer E. Endo-exonuclease of Aspergillus nidulans. Biochem. Cell. Biol. 68:1990;387-392.
29. Lu B., Sakaguchi K. An endo-exonuclease from meiotic tissues of the basidiomycete Coprinus cinereus. J. Biol. Chem. 266:1991;21061-21066.
30. Coututre C., Chow T.Y.-K. Purification and characterization of a mammalian endo-exonuclease. Nucleic Acids Res. 20:1992;4355-4361.
31. Sadekova S., Chow T.Y.-K. Over-expression of the NUD1-coded endo-exonuclease in Saccharomyces cerevisiae enhances DNA recombination and repair. Curr. Genet. 30:1996;50-55.
32. M.J. Fraser, T.Y.-K. Chow, E. Kafer, Nucleases and their control in wild-type and nuh mutants of Neurospora, in: W.M. Generoso, M.D. Shelby, F.J. de Serres (Eds.), DNA Repair and Mutagenesis in Eucaryotes, Plenum, New York, 1980, pp. 109-137.
33. Chow T.Y.-K., Resnick M.A. An endo-exonuclease activity of yeast that requires a functional RAD52 gene. Mol. Gen. Genet. 211:1988;41-48.
34. B. Asefa, P. Kauler, D. Cournoyer, S. Lehnert, T.Y.-K. Chow, Genetic analysis of the yeast NUD1 endo-exonuclease: a role in the repair of DNA double-strand breaks, Curr. Genet. (1998) (in press).
35. Liu G., Lehnert S., Chow T.Y.-K. Mammalian endo-exonuclease activity and its levels in various radiation sensitive cell lines. Mutagenesis. 10(2):1995;91-94.
36. Wahls W.P., Moore P.D. Relative frequencies of homologous recombination between plasmids introduced into DNA repair-deficient and other mammalian somatic cell lines. Somatic Cell Mol. Genet. 16:1990;321-329.
37. Muris D.F.R., Bezzubova O., Buerstedde J.-M., Vreeken K., Balajee A.S., Osgood C.J., Troelstra C., Hoeijmakers J.H.J., Ostermann K., Schmidt H., Natarajan A.T., Eeken J.C.J., Lohman P.H.M., Pastnik A. Cloning of human and mouse genes homologous to RAD52, a yeast gene involved in DNA repair and recombination. Mutat. Res. 315:1994;295-305.
38. Laval F. Expression of the E. coli fpg gene in mammalian cells reduces the mutagenicity of the γ-rays. Nucleic Acids Res. 22:1994;4943-4946.
39. Johnson B.L., Thyagarajan B., Krueger L., Hirsch B., Campbell C. Elevated levels of recombinational DNA repair in human somatic cells expressing the Saccharomyces cerevisiae RAD52 gene. Mutat. Res. 363(3):1996;179-189.
40. van Vliet-Reedijk J.C., Planta R.J. The RHO4a and NUD1 genes on Saccharomyces cerevisiae chromosome XI. Yeast. 9:1993;1139-1147.
41. Ho K.S.Y. The gene dosage effect of the rad52 mutation on X-ray survival curves of tetraploid yeast strains. Mutat. Res. 20:1975;45-51.
42. Swift M., Morrell D., Massey R.B., Chase C.L. Incidence of cancer in families with ataxia-telangiectaseia. New Engl. J. Med. 325:1991;1831-1836.
43. Dokal I. Severe aplastic anemia including Fanconis anemia and dyskeratosis congenita. Curr. Opin. Hematol. 3(6):1996;453-460. Review.
44. Holloman W.K., Holliday R. Studies on a nuclease from Ustilago maydis. I: Purification, properties, and implication in recombination of the enzyme. J. Biol. Chem. 248:1973;8107-8113.
45. Dizdaroglu M. Measurement of radiation-induced damage to DNA at the molecular level. Int. J. Radiat. Biol. 61:1992;175-183.
46. Eastman A. Intrastrand cross-links and sequence specificity in the reaction of cis-dichloro(ethylene-diamine)platinum(II) with DNA. Biochemistry. 24:1985;5027-5032.
47. Brash D.E., Rudolph J.A., Simon J.A., Lin A., McKenna G.J.et al. A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma. Proc. Natl. Acad. Sci. USA. 88:1991;10124-10128.
48. Ley R.D. Photoreactivation in humans. Proc. Natl. Acad. Sci. USA. 91:1993;5012-5016.
49. Xiao W., Chow B.L., Rathgeber L. The repair of DNA methylation damage in Saccharomyces cerevisiae. Curr. Genet. 30:1996;461-468.