Over-expression of the NUD1-coded endo-exonuclease in Saccharomyces cerevisiae enhances DNA recombination and repair

Current Genetics

Volumn 30, Issue 1, 1996, Pages 50-55

  Sadekova, Svetlana ^a   Chow, Terry Y K ^a  

^a MONTREAL GENERAL HOSPITAL   (Canada)

Author keywords

DNA recombination; DNA repair; Endo exonuclease; Mitotic recombination; NUD1 (= NUC2)

Indexed keywords

ENZYME ANTIBODY; EXONUCLEASE; FUNGAL DNA; FUNGAL PROTEIN;

ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; DNA RECOMBINATION; DNA REPAIR; ENZYME ACTIVITY; ENZYME IMMUNOASSAY; FUNGAL GENETICS; GAMMA RADIATION; GENE AMPLIFICATION; GENE FUNCTION; MOLECULAR CLONING; NONHUMAN; NORTHERN BLOTTING; PLASMID; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE;

DEOXYRIBONUCLEASES; DNA REPAIR; GAMMA RAYS; GENE EXPRESSION; GENES, FUNGAL; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

NEUROSPORA CRASSA; SACCHAROMYCES CEREVISIAE;

EID: 0030055675     PISSN: 01728083     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002940050099     Document Type: Article

References (38)

1. Ausubel FM, Brent R, Kingston RE, Moore DD, Seidman JG, Smith JA, Struhl K (eds) (1993) Current protocols in molecular biology. Current protocols. John Wiley & Sons, Inc
2. Bradford MM (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254
3. Chow TYK, Fraser MJ (1979) The major intracellular alkaline deoxyribonuclease activities expressed in wild-type and Rec-like mutants of Neurospora crassa. Can J Biochem 57:889-901
4. Chow TYK, Fraser MJ (1983) Purification and properties of single-strand DNA-binding endo-exonuclease in Neurospora crassa. J Biol Chem 258:12010-12018
5. Chow TYK, Kunz BA (1991) Evidence that an endo-exonuclease controlled by the gene functions in the induction of "petite" mutation in Saccharomyces cerevisiae. Curr Genet 20:39-44
6. Chow TYK, Resnick MA (1983) The identification of a deoxyribonuclease controlled by the RAD52 gene of Saccharomyces cerevisiae. In: Friedberg EC, Bridges BA (eds) Cellular responses to DNA damage. Alan R. Liss, New York, pp 447-455
7. Chow TYK, Resnick MA (1987) Purification and characterization of an endo-exonuclease activity of yeast that requires a functional RAD52 gene. J Biol Chem 262:17659-17667
8. Chow TYK, Resnick MA (1988) An endo-exonuclease activity of yeast that requires a functional RAD52 gene. Mol Gen Genet 211:41-48
9. Chow TYK, Perkins EL, Resnick MA (1992) Yeast RNC1 encodes a chimeric protein, RhoNuc, with a human rho motif and deoxyribonuclease activity. Nucleic Acids Res 20:5215-5221
10. Couture C, Chow TYK (1992) Purification and characterization of a mammalian endo-exonuclease. Nucleic Acids Res 20:4355-4361
11. Dake E, Hofmann TJ, McIntire S, Hudson A, Zassenhaus HP (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263:7691-7702
12. Dujon B et al. (1994) Complete DNA sequence of yeast chromosome XI. Nature 369:371-378
13. Fasullo M, Dave P (1994) Mating type regulates the radiation-associated stimulation of reciprocal translocation events in Saccharomyces cerevisiae. Mol Gen Genet 243:63-70
14. Fraser MJ, Chow TYK, Kafer E (1980) Nucleases and their control in wild-type and nuh mutants of Neurospora. In: Generoso WM, Shelby MD, de Serres FJ (eds) DNA repair and mutagenesis in Eucaryotes. Plenum Publishing Corporation, New York, pp 63-74
15. Game JC (1983) Radiation sensitive mutants and repair in yeast. In: Spencer JFT, Spencer D, Smith A (eds) Yeast genetics, fundamental and applied aspects. Springer-Verlag, New York, pp 109-137
16. Gietz RD, Sugino A (1988) New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74:527-534
17. Goldberg DA (1980) Isolation and partial characterization of the Drosophila alcohol dehydrogenase gene. Proc Natl Acad Sci USA 77:5794-5798
18. Haber JE, Ray BL, Kolb JM, White CI (1993) Rapid kinetics of mismatch repair of heteroduplex DNA that is formed during recombination in yeast. Proc Natl Acad Sci USA 90:3363-3367
19. Hereford LM, Ludwig TR, McLaughlin CS (1981) Cell-cycle regulation of yeast histone mRNA. Cell 24:367-375
20. Ho KSY (1975) The gene dosage effect of the rad52 mutation on X-ray survival curves of tetraploid yeast strains. Mutat Res 20:45-51
21. Holloman WK, Holliday R (1973) Studies on a nuclease from Ustilago maydis. I. Purification, properties, and implication in recombination of the enzyme. J Biol Chem 248:8107-8113
22. Koa H, Fraser MJ, Kafer E (1990) Endo-exonuclease of Aspergillus nidulans. Biochem Cell Biol 68:387-392
23. Kowalczykowski SC, Dixon DA, Eggleston AK, Lauder SD, Rehrauer WM (1994) Biochemistry of homologous recombination in Escherichia coli. Microbiol Rev 58:401-465
24. Kunz BA, Haynes RH (1981) Phenomenology and genetic control of mitotic recombination in yeast. Annu Rev Genet 15:57-89
25. Lehrach H, Diamond D, Wozney JM, Boedtker H (1977) RNA molecular-weight determinations by gel electrophoresis under denaturing conditions, a critical re-examination. Biochemistry 16: 4743-4751
26. Liao H, Thorner J (1980) Yeast mating pheromone alpha factor inhibits adenylate cyclase. Proc Natl Acad Sci USA 77:1898-1902
27. Lu B, Sakaguchi K (1991) An endo-exonuclease from meiotic tissues of the basidiomycete Coprinus cinereus. J Biol Chem 266:21061-21066
28. Moore PD, Simon JR, Wallace LJ, Chow TYK (1993) In vitro recombination in RAD and RNC mutants of Saccharomyces cerevisiae. Curr Genet 23:1-8
29. Ramotar D, Auchincloss AH, Fraser MJ (1987) Nuclear endo-exonuclease of Neurospora crassa. J Biol Chem 262:425-431
30. Resnick MA (1976) The repair of double-strand breaks in DNA: a model involving recombination. J Theor Biol 59:97-106
31. Resnick MA (1987) Investigating the genetic control of biochemical events in meiotic recombination. In: Moens P (ed) Meiosis. Academic Press, New York, pp 157-212
32. Resnick MA, Martin P (1976) The repair of double-stranded breaks in the nuclear DNA of Saccharomyces cerevisiae and its genetic control. Mol Gen Genet 143:119-129
33. Resnick MA, Sugino A, Nitiss J, Chow T (1984 a) DNA polymerases, deoxyribonucleases and recombination during meiosis in Saccharomyces cerevisiae. J Mol Cell Biol 4:2811-2817
34. Resnick MA, Chow TYK, Nitiss J, Game JC (1984 b) Changes in the chromosomal DNA of yeast during meiosis in repair mutants and the possible role of a deoxyribonuclease. Cold Spring Harbor Symp Quant Biol 49:639-649
35. Rose MD, Winston F, Hieter P eds. (1990) Yeast genetics laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York
36. Thelen MP, Onel K, Holloman WK (1994) The Rec1 gene of Ustilago maydis involved in the cellular response to DNA damage encodes an exonuclease. J Biol Chem 269:747-754
37. Tomkinson AE, Linn S (1986) Purification and properties of a single-strand-specific endonuclease from mouse cell mitochondria. Nucleic Acids Res 14:9579-9593
38. Vliet-Reedijk van JC, Planta RJ (1993) The RHO4a and NUD1 genes on Saccharomyces cerevisiae chromosome XI. Yeast 9:1139-1147