p53 compound heterozygosity in a severely affected child with Li-Fraumeni Syndrome

Oncogene

Volumn 18, Issue 27, 1999, Pages 3970-3978

  Quesnel, Susan ^a   Verselis, Sigitas ^b   Portwine, Carol ^a   Garber, Judy ^b   White, Marga ^c   Feunteun, Jean ^d   Malkin, David ^a   Li, Frederick P ^b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b DANA FARBER CANCER INSTITUTE   (United States)

^c Oncormed Inc   (United States)

^d INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Functional assays; Germline mutations; Li Fraumeni Syndrome; p53

Indexed keywords

PROTEIN P53;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; CELL GROWTH; CHILDHOOD CANCER; FAMILIAL CANCER; HETEROZYGOSITY; HUMAN; HUMAN CELL; MULTIPLE CANCER; PRIORITY JOURNAL;

ADULT; CELL DIVISION; CHILD; CHILD, PRESCHOOL; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DNA, RIBOSOMAL; FEMALE; GENE EXPRESSION REGULATION; GENES, P53; GERM-LINE MUTATION; HETEROZYGOTE DETECTION; HUMANS; LI-FRAUMENI SYNDROME; MALE; MULTIGENE FAMILY; PEDIGREE; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED; VARIATION (GENETICS);

EID: 0033536239     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202783     Document Type: Article

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