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Volumn 64, Issue 1, 1999, Pages 23-27

Total synthesis of myxalamide A

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALDEHYDE; ALKYNE; ALLYL SULFIDE; BORANE DERIVATIVE; CARBON; FUNCTIONAL GROUP; IMIDE; MYXALAMIDE A; POLYENE ANTIBIOTIC AGENT; SULFOXIDE; UNCLASSIFIED DRUG;

EID: 0033534602     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo9813742     Document Type: Article
Times cited : (75)

References (54)
  • 1
    • 0003905731 scopus 로고
    • Morrison, J. D., Ed.; Academic Press: New York
    • Heathcock, C. H. In Asymmetric Synthesis; Morrison, J. D., Ed.; Academic Press: New York, 1984, Vol. 3.
    • (1984) Asymmetric Synthesis , vol.3
    • Heathcock, C.H.1
  • 19
    • 0344580685 scopus 로고    scopus 로고
    • Ph.D. Thesis, University of California, Berkeley
    • For details of this approach, see: Mapp, A. K. Ph.D. Thesis, University of California, Berkeley, 1997.
    • (1997)
    • Mapp, A.K.1
  • 24
  • 31
    • 84958315401 scopus 로고
    • 3) workup, but careful chromatography of the crude product was necessary due to the presence of undesirable diastereomers. Evans, D. A.; Rieger, D. L.; Bilodeau, M. T.; Urpi, F. J. Am. Chem. Soc. 1991, 113, 1047.
    • (1991) J. Am. Chem. Soc. , vol.113 , pp. 1047
    • Evans, D.A.1    Rieger, D.L.2    Bilodeau, M.T.3    Urpi, F.4
  • 41
    • 0344580680 scopus 로고    scopus 로고
    • note
    • Phosphonate 31 was prepared by heating trimethyl phosphite and 3-(trimethylsilyl)propynyl bromide followed by deprotonation with BuLi and subsequent treatment with MeI. Phosphonate 32 was prepared in analogous fashion starting with triisopropyl phosphite.
  • 54
    • 0345011660 scopus 로고    scopus 로고
    • note
    • 13C NMR spectrum of synthetic 1 did not match that reported in the original isolation paper (ref 4a). However, this discrepancy proved to be the result of a typographical error in the isolation paper as confirmed by Dr. R. Jansen by personal communication.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.