The design of (-)-(S)-2-nitrooxyethyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxyla te: A cardioselective positive inotropic derivative of Bay K 8644

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 17, 1999, Pages 2613-2614

  Shan, Rudong ^a   Knaus, Edward E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; 2 NITROOXYETHYL 1,4 DIHYDRO 2,6 DIMETHYL 3 NITRO 4 (2 TRIFLUOROMETHYLPHENYL)PYRIDINE 5 CARBOXYLATE; CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL STIMULATING AGENT; CARBOXYLIC ACID DERIVATIVE; LEAD; NITRIC OXIDE; UNCLASSIFIED DRUG;

ARTICLE; CONGESTIVE HEART FAILURE; DRUG DESIGN; PARTIAL DRUG SYNTHESIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

3-PYRIDINECARBOXYLIC ACID, 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-(TRIFLUOROMETHYL)PHENYL)-, METHYL ESTER; CALCIUM CHANNEL AGONISTS; HEART; MUSCLE, SMOOTH; MYOCARDIAL CONTRACTION; NICOTINIC ACIDS; NITRIC OXIDE;

EID: 0033530094     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00445-X     Document Type: Article

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