New 1,4-dihydropyridines conjugated to furoxanyl moieties, endowed with both nitric oxide-like and calcium channel antagonist vasodilator activities

Journal of Medicinal Chemistry

Volumn 41, Issue 27, 1998, Pages 5393-5401

  Di Stilo, Antonella ^a   Visentin, Sonja ^a   Cena, Clara ^a   Gasco, Andréa Marcello ^a   Ermondi, Giuseppe ^a   Gasco, Alberto ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 4 PHENYLPYRIDINE DERIVATIVE; [1,2,4]OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; CALCIUM ANTAGONIST; CALCIUM ION; FURAZAN DERIVATIVE; GUANYLATE CYCLASE INHIBITOR; METHYLENE BLUE; NIFEDIPINE; NITRENDIPINE; NITRIC OXIDE; UNCLASSIFIED DRUG; VASODILATOR AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM ANTAGONISM; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; ENZYME INHIBITION; FEMALE; NONHUMAN; RAT; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION; VASODILATATION;

ANIMALS; AORTA, THORACIC; BINDING, COMPETITIVE; CALCIUM CHANNEL BLOCKERS; CEREBRAL CORTEX; DIHYDROPYRIDINES; ENZYME INHIBITORS; GUANYLATE CYCLASE; MALE; METHYLENE BLUE; MUSCLE CONTRACTION; MUSCLE, SMOOTH, VASCULAR; NIFEDIPINE; NITRIC OXIDE DONORS; OXADIAZOLES; QUINOXALINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP; VASODILATOR AGENTS;

EID: 0032585546     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9803267     Document Type: Article

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