Are research ethics bad for our mental health?

New England Journal of Medicine

Volumn 340, Issue 18, 1999, Pages 1427-1430

  Michels, Robert ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLISM; DECISION MAKING; DEPRESSION; ETHICS; HUMAN; INFORMED CONSENT; LAW SUIT; MANIC DEPRESSIVE PSYCHOSIS; MEDICAL RESEARCH; MENTAL DISEASE; OBSESSION; PRIORITY JOURNAL; REVIEW; SCHIZOPHRENIA;

BIOMEDICAL AND BEHAVIORAL RESEARCH; CLINICAL APPROACH/SOURCE; COMMITTEE MEMBERSHIP; COMPETENCE; FEDERAL GOVERNMENT; GOVERNMENT REGULATION; LEGAL APPROACH; MENTAL HEALTH THERAPIES; MENTALLY ILL; NATIONAL BIOETHICS ADVISORY COMMISSION; RESEARCH SUBJECTS; THERAPEUTIC RESEARCH; UNITED STATES;

ADVISORY COMMITTEES; BIOETHICS; COMMITTEE MEMBERSHIP; ETHICS COMMITTEES, RESEARCH; ETHICS, MEDICAL; FEDERAL GOVERNMENT; GOVERNMENT REGULATION; HISTORY, 20TH CENTURY; HUMAN EXPERIMENTATION; HUMANS; INFORMED CONSENT; MENTAL COMPETENCY; MENTAL DISORDERS; MENTALLY ILL PERSONS; MORAL OBLIGATIONS; RESEARCH; RESEARCH SUBJECTS; THERAPEUTIC HUMAN EXPERIMENTATION; THIRD-PARTY CONSENT; UNITED STATES; WITHHOLDING TREATMENT;

EID: 0033529020     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199905063401811     Document Type: Review

References (20)

1. World Health Organization. The global burden of disease. Cambridge, Mass.: Harvard University Press, 1997.
2. Michels R, Marzuk PM. Progress in psychiatry. N Engl J Med 1993; 329:552-60, 628-38.
3. Datagram: NIH extramural support to institutions of higher education by department. Psychiatr Rep 1995;10(2):19.
4. Trials of war criminals before the Nuremberg Military Tribunals under Control Council Law No. 10, Nuremberg, October 1946-April 1949. Vol. 2. Washington, D.C.: Government Printing Office, 1949:181-2.
5. Beecher HK. Experimentation in man. American lecture series publication no. 52. Springfield, Ill.: Charles C Thomas, 1959.
6. World Medical Association. Declaration of Helsinki: recommendations guiding physicians in biomedical research involving human subjects. JAMA 1997;277:925-6.
7. National Commission for the Protection of Human Subjects of Biomedical and Behavioral Research. Report and recommendations: research involving those institutionalized as mentally infirm. Washington, D.C.: Government Printing Office, 1978:58.
8. Wolpe PR, Moreno J, Caplan AL. Ethical principles and history. In: Pincus HA, Lieberman JA, Ferris S, eds. Ethics in psychiatric research. Washington, D.C.: American Psychiatriac Association, 1999:11.
9. Protection of human subjects. In: Pincus HA, Lieberman JA, Ferris S, eds. Ethics in psychiatric research. Washington, D.C.: American Psychiatric Association, 1999:282.
10. Research involving persons with mental disorders that may affect decisionmaking capacity. Rockville, Md.: National Bioethics Advisory Commission, 1998.
11. Evaluation of human subject protections in schizophrenia research conducted by the University of California, Los Angeles, 1994. Bethesda, Md.: Office for Protection from Research Risks, 1994.
12. T.D., et al. v. New York State Office of Mental Health, et al., 626 N.Y.S. 2d 1015 (N.Y. Sup. Ct. 1995).
13. Kong D, Whitaker R. Doing harm: research on the mentally ill. Boston Globe. November 15-18, 1998:A1.
14. Appelbaum PS. Rethinking the conduct of psychiatric research. Arch Gen Psychiatry 1997;54:117-20.
15. Grisso T, Appelbaum PS. The MacArthur Treatment Competence Study. III. Abilities of patients to consent to psychiatric and medical treatments. Law Hum Behav 1995;19:149-74.
16. Sugarman J, Kass NE, Goodman SN, Perentesis P, Fernandes P, Faden RR. What patients say about medical research. IRB 1998;20(4):1-7.
17. New York State Department of Health Advisory Work Group on Human Subject Research Involving the Protected Classes. Recommendations on the oversight of human subject research involving the protected classes. Albany: New York State Department of Health, 1998.
18. Final report of the Attorney General's Working Group on Research Involving Decisionally Incapacitated Subjects. Baltimore: Office of the Maryland Attorney General, 1998.
19. Marshall E. Panel tightens rules on mental disorders. Science 1998; 282:1617.
20. Beecher HK. Ethics and clinical research. N Engl J Med 1966;274: 1354-60.