Regional heparinization via simultaneous separation and reaction in a novel Taylor-Couette flow device

Biotechnology and Bioengineering

Volumn 63, Issue 5, 1999, Pages 618-624

  Ameer, G A ^a,b   Raghavan, S ^a   Sasisekharan, R ^b   Harmon, W ^c   Cooney, C L ^a,b   Langer, R ^a,b  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Agarose bioreactor; Blood detoxification; Fluidized bed; Heparin neutralization; Heparinase; Taylor Couette flow

Indexed keywords

BLOOD; ENZYME IMMOBILIZATION; FLUIDIZATION; FLUIDIZED BEDS; PACKED BEDS; SALINE WATER; VORTEX FLOW;

AGAROSE; BLOOD DETOXIFICATION; HEPARINIZATION; TAYLOR-COUETTE FLOW; VORTEX FLOW PLASMAPHERETIC REACTORS (VFPR);

BIOREACTORS;

HEPARIN; HEPARIN LYASE; IMMOBILIZED ENZYME; ISOENZYME;

ARTICLE; BIOREACTOR; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DEGRADATION; DRUG DELIVERY SYSTEM; ENZYME IMMOBILIZATION; FEASIBILITY STUDY; HEPARINIZATION; HUMAN; PLASMAPHERESIS; REACTOR SAFETY; RELIABILITY; VALIDATION PROCESS;

BIOCOMPATIBLE MATERIALS; BIOREACTORS; BLOOD; ENZYMES, IMMOBILIZED; EQUIPMENT DESIGN; HEPARIN; HEPARIN LYASE; HUMANS;

EID: 0033526548     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19990605)63:5<618::AID-BIT12>3.0.CO;2-3     Document Type: Article

References (13)

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