No evidence of brain cell degeneration after long-term sleep deprivation in rats

Brain Research

Volumn 840, Issue 1-2, 1999, Pages 184-193

  Cirelli, Chiara ^a   Shaw, Paul J ^a   Rechtschaffen, Allan ^b   Tononi, Giulio ^a  

^a NEUROSCIENCES INSTITUTE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Apoptosis; cDNA array; Cell death; Fluoro Jade; Glutamate; TUNEL

Indexed keywords

COMPLEMENTARY DNA; FLUOROCHROME; GLUTAMIC ACID; MESSENGER RNA; PHOSPHORUS 32;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; CELL DEATH; CONTROLLED STUDY; DNA DAMAGE; ISOTOPE LABELING; MALE; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; RAT; SLEEP DEPRIVATION; SLEEP WAKING CYCLE;

ANIMALS; APOPTOSIS; BRAIN; CELL DEATH; DNA FRAGMENTATION; FLUORESCENT DYES; GENE EXPRESSION; IN SITU NICK-END LABELING; MALE; NERVE DEGENERATION; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; REFERENCE VALUES; SLEEP DEPRIVATION; STAINING AND LABELING; STRESS; TIME FACTORS;

EID: 0033523431     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(99)01768-0     Document Type: Article

References (48)

1. Aston-Jones G., Bloom F.E. Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle. J. Neurosci. 1:1981;876-886.
2. Basheer R., Magner M., McCarley R.W., Shiromani P.J. REM sleep deprivation increases the levels of tyrosine hydroxylase and norepinephrine transport mRNA in the locus coeruleus. Mol. Brain Res. 57:1998;235-240.
3. Bentivoglio M., Grassi-Zucconi G. The pioneering experimental studies on sleep deprivation. Sleep. 2:1997;570-576.
4. Bergmann B.M., Winter J.B., Rosenberg R.S., Rechtchaffen A. NREM sleep with low-voltage EEG in the rat. Sleep. 10:1987;1-11.
5. Bergmann B.M., Kushida C.A., Everson C.A., Gilliland M.A., Obermeyer W., Rechtchaffen A. Sleep deprivation in the rat: II Methodology. Sleep. 12:1989;5-12.
6. Bergmann B.M., Everson C.A., Kushida C.A., Fang V.S., Leitch C.A., Schoeller D.A., Refetoff S., Rechtchaffen A. Sleep deprivation in the rat: V. Energy use and mediation. Sleep. 12:1989;31-41.
7. Bergmann B.M., Seiden S.L., Landis C.A., Gilliland M.A., Rechtchaffen A. Sleep deprivation in the rat. XVIII. Effect of sleep deprivation on regional levels of rat brain monoamines and their metabolites. Sleep. 17:1994;583-589.
8. Berridge C.W., Abercrombie E.A., Kuczenski R.T., Foote S.L. Relationship between locus coeruleus neuronal activity and norepinephrine release in neocortex. Soc. Neurosci. Abstr. 22:1996;240-243.
9. Borbély A.A., Neuhaus H.U. Daily pattern of sleep, motor activity and feeding in the rat: effects of regular and gradually extended photoperiods. J. Comp. Physiol. 124:1978;1-14.
10. Bowyer J.F., Peterson S.L., Rountree R.L., Tor-Agbidye J., Wang G.J. Neuronal degeneration in rat forebrain resulting from D-amphetamine-induced convulsions is dependent on seizure severity and age. Brain Res. 809:1998;77-90.
11. Cirelli C., Tononi G. Changes in gene expression in the cerebral cortex of rats after short- and long-term total sleep deprivation. Sleep. 22(Suppl.):1999;113.
12. Cirelli C., Tononi G. Changes in anti-phosphoserine and anti-phosphothreonine antibody binding during the sleep-waking cycle and after lesions of the locus coeruleus. Sleep Res. Online. 1:1998;11-18.
13. Cirelli C., Tononi G. Differences in gene expression between sleep and waking as revealed by mRNA differential display. Mol. Brain Res. 56:1998;293-305.
14. D'Almeida V., Hipólide D.C., Azzalis L.A., Lobo L.L., Junqueira V.B.C., Tufik S. Absence of oxidative stress following paradoxical sleep deprivation in rats. Neurosci. Lett. 235:1997;25-28.
15. Eastman C.I., Rechtschaffen A. Circadian temperature and wake rhythms of rats exposed to prolonged continuous illumination. Physiol. Behav. 31:1983;417-427.
16. Eiland M.M., Gilliland M., Bergmann B.M., Rechtschaffen A., Siegel J. Neuronal degeneration in sleep deprived rats. Sleep. 21:1998;2.
17. Everson C.A., Smith C.B., Sokoloff L. Effects of prolonged sleep deprivation on local rates of cerebral energy metabolism in freely moving rats. J. Neurosci. 14:1994;6769-6778.
18. Feng P.-F., Bergmann B.M., Rechtschaffen A. Effect of total sleep deprivation on microtubule density in rat brain. Sleep Res. 24:1995;443.
19. Feng P.-F., Bergmann B.M., Rechtschaffen A. Effect of total sleep deprivation on neuronal ultrastructure in the rat. Sleep Res. 25:1996;466.
20. Gavrieli Y., Sherman Y., Ben Sasson S.A. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:1992;493-501.
21. Gilliland M., Wold L., Wollman R., Eschenbach K., Rechtschaffen A. Pathology in sleep deprived rats is not reflected in histologic abnormalities. Sleep. 13:1984;190.
22. J.A. Horne, Why we sleep. The functions of sleep in humans and other mammals, Oxford University Press, Oxford, 1988.
23. Inoué S., Honda K., Komoda Y. Sleep as neuronal detoxification and restitution. Behav. Brain Res. 69:1995;91-96.
24. Kripke D.F., Simons R.N., Garfinkel L., Hammond E.C. Short and long sleep and sleeping pills. Is increased mortality associated? Arch. Gen. Psych. 36:1979;103-116.
25. Labat-Moleur F., Guillermet C., Lorimier P., Robert C., Lantuejoul S., Brambilla E., Negoescu A. TUNEL apoptotic cell detection in tissue sections: critical evaluation and improvement. J. Histoch. Cytochem. 46:1998;327-334.
26. Landis C.A., Collins B.J., Cribbs L.L., Sukhatme V.P., Bergmann B.M., Rechtchaffen A., Smalheiser N.R. Expression of Egr-1 in the brain of sleep deprived rats. Mol. Brain Res. 17:1993;300-306.
27. Leproult R., Copinschi G., Buxton O., Cauter E.V. Sleep loss results in an elevation of cortisol levels the next evening. Sleep. 20:1997;865-870.
28. Maher P., Davis J.B. The role of monoamine metabolism in oxidative glutamate toxicity. J. Neurosci. 16:1996;6394-6401.
29. Mamelak M. Neurodegeneration, sleep, and cerebral energy metabolism: a testable hypothesis. J. Ger. Psych. Neurol. 10:1997;29-32.
30. Novelli A., Reilley J.A., Lysko P.G., Henneberry R.C. Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced. Brain Res. 451:1988;205-212.
31. G. Paxinos, C. Watson, The rat brain in stereotaxic coordinates. Academic Press, New York, 1986.
32. Piantadosi C.A., Zhang J., Levin E.D., Folz R.J., Schmechel D.E. Apoptosis and delayed neuronal damage after carbon monoxide poisoning in the rat. Exp. Neurol. 147:1997;103-114.
33. Pompeiano M., Cirelli C., Tononi G. Immediate early genes in spontaneous wakefulness and sleep: expression of c-fos and NGFI-A mRNA and protein. J. Sleep Res. 3:1994;65-81.
34. Portas C.M., Bjorvatn B., Fagerland S., Gronli J., Mundal V., Sorensen E., Ursin R. On-line detection of extracellular levels of serotonin in dorsal raphe nucleus and frontal cortex over the sleep/wake cycle in the freely moving rat. Neuroscience. 83:1998;807-814.
35. Qin Z.-H., Wang Y., Chase T.N. Stimulation of N-methyl-D-aspartate receptors induces apoptosis in rat brain. Brain Res. 725:1996;166-176.
36. Rechtschaffen A., Gilliland M.A., Bergmann B.M., Winter J.B. Physiological correlates of prolonged sleep deprivation in rats. Science. 221:1983;182-184.
37. Rechtschaffen A., Bergmann B.M. Sleep deprivation in the rat by the disk-over-water method. Behav. Brain Res. 69:1995;55-63.
38. Reimund E. The free radical flux theory of sleep. Med. Hypotheses. 43:1994;231-233.
39. Sapolsky R.M. Glucocorticoids, stress and exacerbation of excitotoxic neuron death. Sem. Neurosci. 6:1994;323-331.
40. Schmued L.C., Albertson C., Slikker W. Jr. Fluoro-Jade: a novel fluorochrome for the sensitive and reliable histochemical localization of neuronal degeneration. Brain Res. 751:1997;37-46.
41. Sloviter R.S., Lowenstein D.H. Heat shock protein expression in vulnerable cells of the rat hippocampus as an indicator of excitation-induced neuronal stress. J. Neurosci. 12:1992;3004-3009.
42. Sloviter R.S., Sollas A.L., Dean E., Neubort S. Adrenalectomy-induced granule cell degeneration in the rat hippocampal dentate gyrus: characterization of an in vivo model of controlled neuronal death. J. Neurosci. 330:1993;324-336.
43. Sloviter R.S., Dean E., Neubort S. An electron microscopic analysis of adrenalectomy-induced hippocampal granule cell degeneration in the rat: apoptosis in the adult central nervous system. J. Neurosci. 330:1993;337-351.
44. Tsai L.-L., Bergmann B.M., Perry B.D., Rechtchaffen A. Effects of chronic sleep deprivation on central noradrenergic receptors in rat brain. Brain Res. 602:1993;221-227.
45. Tsai L.-L., Bergmann B.M., Perry B.D., Rechtchaffen A. Effects of chronic sleep deprivation on central cholinergic receptors in rat brain. Brain Res. 642:1994;95-103.
46. W.B. Webb, Theories of sleep functions and some clinical implications, in: R. Drucker-Colin, M. Shkurovich, M.B. Sterman (Eds.), The Functions of Sleep, Academic Press, New York, 1979, pp. 19-35.
47. Wyllie A.H., Kerr J.F.R., Currie A.R. Cell death: the significance of apoptosis. Int. Rev. Cytol. 68:1980;251-306.
48. Zhu R.L., Graham S.H., Jin K., Stetler R.A., Simon R.P., Chen J. Kainate induces the expression of the DNA damage-inducible gene, GADD45, in the rat brain. Neuroscience. 81:1997;707-720.