Biosynthetic studies on the α-glucosidase inhibitor acarbose in actinoplanes sp.: 2-epi-5-epi-valiolone is the direct precursor of the valienamine moiety

Journal of the American Chemical Society

Volumn 121, Issue 30, 1999, Pages 6973-6983

  Mahmud, Taifo ^d   Tornus, Ingo ^a,d   Egelkrout, Erin ^b,d   Wolf, Eckardt ^c,d   Uy, Charmaine ^d   Floss, Heinz G ^d   Lee, Sungsook ^d  

^a BAYER PHARMA AG   (Germany)

^b NORTH CAROLINA STATE UNIVERSITY   (United States)

^c Toronto Research Chemicals   (Canada)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 VALIOLONE; ACARBOSE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; DEHYDRATION; DRUG STRUCTURE; DRUG SYNTHESIS; PROTON NUCLEAR MAGNETIC RESONANCE; REDUCTION; STEREOCHEMISTRY;

EID: 0033523256     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja991102w     Document Type: Article

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