Characterisation and mitochondrial localisation of AUH, an AU-specific RNA-binding enoyl-CoA hydratase

Gene

Volumn 228, Issue 1-2, 1999, Pages 85-91

  Brennan, Lyndall E ^a   Nakagawa, Junichi ^a   Egger, Denise ^a   Bienz, Kurt ^a   Moroni, Christoph ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Cell localisation; Enzyme; Expression; mRNA stability

Indexed keywords

ENOYL COENZYME A HYDRATASE; RNA BINDING PROTEIN;

ANIMAL CELL; ARTICLE; EARLY RESPONSE GENE; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LOCALIZATION; FATTY ACID OXIDATION; IMMUNOELECTRON MICROSCOPY; MITOCHONDRIAL MEMBRANE; MOLECULAR CLONING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA DEGRADATION; ROUGH ENDOPLASMIC RETICULUM; TISSUE SPECIFICITY; TRANSCRIPTION REGULATION;

AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; BLOTTING, WESTERN; DNA, COMPLEMENTARY; ENOYL-COA HYDRATASE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; KIDNEY; MALE; MAST CELLS; MICE; MICE, INBRED BALB C; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; RNA, MESSENGER; RNA-BINDING PROTEINS; SEQUENCE ANALYSIS, DNA; SEQUENCE HOMOLOGY, AMINO ACID; TISSUE DISTRIBUTION;

ANIMALIA; MURINAE;

EID: 0033522167     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00003-7     Document Type: Article

References (30)

1. Abe R., Sakashita E., Yamamoto K., Sakamoto H. Two different RNA binding activities for the AU-rich element and the poly(A) sequence of the mouse neuronal protein mHuC. Nucleic Acids Res. 24:(24):1996;4895-4901.
2. Altman L.G., Schneider B.G., Papermaster D.S. Rapid embedding of tissues in Lowicryl KM4 for immunoelectron microscopy. J. Histochem. Cytochem. 32:1984;1217-1223.
3. Bienz K., Egger D., Pasamontes L. Association of poliovirus proteins of the P2 genomic region with the viral replication complex and virus-induced membrane synthesis as visualised by electron microscopic immunocytochemistry and autoradiography. Virology. 160:1987;220-226.
4. Chen C.-Y.A., Shyu A.-B. AU-rich elements: characterization and importance in mRNA degradation. Trends Biochem.Sci. 20:1995;465-470.
5. Chen C.-Y.A., Xu N., Shyu A.-B. mRNA decay mediated by two distinct AU- rich elements from c-fos and granulocyte-macrophage colony-stimulating factor transcripts: different deadenylation kinetics and uncoupling from translation. Mol. Cell. Biol. 15:1995;5777-5788.
6. Curatola A.M., Nadal M.S., Schneider R.J. Rapid degradation of AU-Rich Element (ARE) mRNAs is activated by ribosome transit and blocked by secondary structure at any position 5′ to the ARE. Mol. Cell. Biol. 15:(11):1995;6331-6340.
7. Engel C.K., Mathieu M., Zeelen J.P., Hitunen J.K., Wierenga R.K. Crystal structure of enoyl-coenzyme A (CoA) hydratase at 2.5 Å resolution: a spiral fold defines the CoA-binding pocket. EMBO J. 15:(19):1996;5135-5145.
8. Fan X.C., Myer V., Steitz J.A. AU-rich elements target small nuclear RNAs as well as mRNAs for rapid degradation. Genes Dev. 11:1997;2557-2568.
9. Fan X.C., Steitz J.A. Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs. EMBO J. 17:(12):1998;3448-3460.
10. Hentze M.W. Enzymes as RNA-binding proteins: a role for (di)nucleotide-binding domains. Trends Biochem. Sci. 19:1994;101-103.
11. Kamijo T., Aoyama T., Miyazaki J., Hashimoto T. Molecular cloning of the cDNAs for the subunits of rat mitochindrial fatty acid β-oxidation multienzyme complex. J.Biol.Chem. 268:1993;26452-26460.
12. Kanazawa M., Ohtake A., Abe H., Yamamoto S., Satoh Y., Takayanagi M., Niimi H., Mori M., Hashimoto T. Molecular cloning and sequence analysis of the cDNA for human mitochondrial short-chain enoyl-CoA hydratase. Enzyme-Protein. 47:1993;9-13.
13. Klausner R.D., Rouault T.A., Harford J.B. Regulating the fate of mRNA: the control of cellular iron metabolism. Cell. 72:1993;19-28.
14. Kozak M. At least six nucleotides preceding the AUG initiator codon enhance translation in mammalian cells. J. Mol. Biol. 196:1987;947-950.
15. Lehner C.F., Kurer V., Eppenberger H.M., Nigg E.A. The nuclear lamin protein family in higher vertebrates: identification of quantitatively minor lamin proteins by monoclonal antibodies. J. Biol. Chem. 261:1986;13293-13301.
16. Ma W.J., Chung S., Furneaux H. The Elav-like proteins bind to AU-rich elements and to the poly(A) tail of mRNA. Nucleic Acids Res. 25:(18):1997;3564-3569.
17. Minami-Ishii N., Taketani S., Osumi T., Hashimoto T. Molecular cloning and sequence analysis of the cDNA for rat mitochondrial enoyl-CoA hydratase. Eur. J. Biochem. 185:1989;73-78.
18. Mizushima S., Nagata S. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18:(17):1990;5322.
19. Müller-Newen G., Janssen U., Stoffel W. Enoyl-CoA hydratase and isomerase form a superfamily with a common active-site glutamate residue. Eur. J. Biochem. 228:1995;68-73.
20. +-binding region (Rossmann fold). J. Biol. Chem. 270:1995;2755-2763.
21. Nakagawa J., Moroni C. A twenty amino acid autonomous RNA-binding domain contained in a enoyl-CoA hydratase. Eur. J. Biochem. 244:1997;890-899.
22. Nakagawa J., Waldner H., Meyer-Monard S., Hofsteenge J., Jenö, Moroni C. AUH, a gene encoding an AU-specific RNA binding protein with intrinsic enoyl-CoA hydratase activity. Proc. Natl. Acad. Sci. USA. 92:1995;2051-2055.
23. Nanbu R., Kubo T., Hashimoto T., Natori S. Purification of an AU-Rich RNA binding protein from Sarcophaga peregrina (flesh fly) and its identification as a thiolase. J. Biochem. 114:1993;432-437.
24. Peng S.S.-Y., Chen C.-Y.A., Shyu A.-B. RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein. EMBO J. 17:(12):1998;3461-3470.
25. Ross J. mRNA stability in mammalian cells. Microbiol. Rev. 59:1995;423-450.
26. Schweizer A., Rohrer J., Slot J.W., Geute H.J., Kornfeld S. Reassessment of the subcellular localisation of p63. J. Cell Sci. 108:(6):1995;2477-2485.
27. Seiser C., Posch P., Thompson N., Kühn L. Effect of transcription inhibitors on the iron-dependent degradation of transferrin receptor mRNA. J. Biol. Chem. 270:(49):1995;29400-29406.
28. Shaw G., Kamen R. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell. 46:1986;659-667.
29. Sirenko O., Lofquist A.K., DeMaria C.T., Morris J.S., Brewer G., Haskill J.S. Adhesion-dependent regulation of an A+U-rich element-binding activity associated with AUF1. Mol. Cell. Biol. 17:(7):1997;3898-3906.
30. Winstall E., Gamache M., Raymond V. Rapid mRNA degradation mediated by the c-fos 3′UTR AU-rich element and that mediated by the granulocyte-macrophage colony-stimulating factor 3′ AU-rich element occur through similar polysome-associated mechanisms. Mol. Cell. Biol. 15:(7):1995;3796-3804.