Reduced lecithin:retinol acyl transferase activity in cultured squamous cell carcinoma lines results in increased substrate-driven retinoic acid synthesis

Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids

Volumn 1436, Issue 3, 1999, Pages 479-490

  Jurukovski, Vladimir ^a   Simon, Marcia ^a,b  

^a STONY BROOK UNIVERSITY   (United States)

^b STONY BROOK UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Carcinoma; Esterification; Keratinocyte; Metabolism; Retinol

Indexed keywords

DEHYDRORETINOL; LECITHIN RETINOL ACYLTRANSFERASE; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; RETINOIC ACID; RETINOIC ACID RECEPTOR; RETINOL; RETINOL ACYLTRANSFERASE; RETINOL ESTER; RETINYL PALMITATE ESTERASE; RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ESTERIFICATION; HUMAN; HUMAN CELL; HYDROLYSIS; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN CANCER; SQUAMOUS CELL CARCINOMA; VITAMIN METABOLISM;

ACYLTRANSFERASES; BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; CELL LINE; DNA PRIMERS; GENE EXPRESSION; HUMANS; KERATINOCYTES; KINETICS; SUBSTRATE SPECIFICITY; TRANSGLUTAMINASES; TRETINOIN; TUMOR CELLS, CULTURED; VITAMIN A;

EID: 0033521720     PISSN: 13881981     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0005-2760(98)00154-4     Document Type: Article

References (55)

1. R.K. Randolph, G. Siegenthaler, Vitamin A homeostasis in human epidermis: native retinoid composition and metabolism, in: H. Nau, W.S. Blaner (Eds.), Retinoids, Springer-Verlag, Berlin, 1998, in press.
2. Vahlquist A., Torma H. Retinoids and keratinization. Int. J. Dermatol. 27:1988;81-95.
3. Asselineau D., Barnard B.A., Beiklly C., Darmon M. Retinoic acid improves epidermal morphogenesis. Dev. Biol. 133:1989;322-335.
4. Braakhuis B.J.M., Klaassen I., van der Leede B.M., Cloos J., Brakenhoff T.H., Copper M.P., Teerlink T., Hendriks H.F.J., van der Saag P.T., Snow G.B. Retinoid metabolism and all-trans retinoic acid-induced growth inhibition in head and neck squamous cell carcinoma cell lines. Br. J. Cancer. 76:1997;189-197.
5. Vettermann O., Siegenthaler G., Schweizer J. Retinoic acid signaling cascade in differentiating murine epidermal keratinocytes: alterations in papilloma- and carcinoma-derived cell lines. Mol. Carcinog. 20:1997;58-67.
6. Petkovich M., Brand N.J., Krust A., Chambon P. A human retinoic acid receptor which belongs to the family of nuclear receptors. Nature. 330:1987;440-450.
7. Giguere V. Retinoic acid receptors and cellular retinoid binding proteins. Complex interplay in retinoid signaling. Endocr. Rev. 15:1994;61-79.
8. Giguere V., Ong E.S., Segui P., Evans R.M. Identification of a receptor for the morphogen retinoic acid. Nature. 330:1987;624-629.
9. D.J. Mangelsdorf, K. Umesono, R.M. Evans, The retinoid receptors, in: M.B. Sporn, A.B. Roberts, D.S. Goodman (Eds.), The Retinoids: Biology, Chemistry and Medicine, 2nd edn., Raven Press, New York, 1994, pp. 319-350.
10. Torma H., Asselineau D., Andersson E., Martin B., Reiniche P., Chambon P., Shroot B., Darmon M., Vahlquist A. Biologic activities of retinoic acid and 3,4-didehydroretinoic acid in human keratinocytes are similar and correlate with receptor affinities and transactivation properties. J. Invest. Dermatol. 102:1994;49-54.
11. D.S. Goodman, Plasma retinol binding protein, in: M.B. Sporn, A.B. Roberts, D.S. Goodman (Eds.), The Retinoids, vol. 2, Academic Press, Orlando, FL, 1984, pp. 41-88.
12. D.R. Soprano, W.S. Blaner, Plasma retinol binding proteins, in: M.B. Sporn, A.B. Roberts, D.S. Goodman (Eds.), The Retinoids: Biology, Chemistry and Medicine, 2nd edn., Raven Press, New York, 1994, pp. 257-281.
13. Torma H., Vahlquist A. Vitamin A esterification in human epidermis: a relation to keratinocyte differentiation. J. Invest. Dermatol. 94:1990;132-138.
14. Randolph R.K., Simon M. Characterization of retinol metabolism in cultured human keratinocytes. J. Biol. Chem. 268:1993;9198-9205.
15. Kurlandsky S.B., Duell E.A., Kang S., Voorhees J.J. Auto-regulation of retinoic acid biosynthesis through regulation of retinol esterification in human keratinocytes. J. Biol. Chem. 271:1996;15346-15352.
16. W.S. Blaner, J.A. Olson, Retinol and retinoic acid metabolism, in: M.B. Sporn, A.B. Roberts, D.S. Goodman (Eds.), The Retinoids: Biology, Chemistry and Medicine, 2nd edn., Raven Press, New York, 1994, pp. 229-256.
17. Randolph R.K., Ross A.C. Vitamin A status regulates hepatic lecithin:retinol acyltransferase activity in rats. J. Biol. Chem. 266:1991;16453-16457.
18. Randolph R.K., Simon M. All-trans retinoic acid regulates retinol and 3,4-didehydroretinol metabolism in cultured human keratinocytes. J. Invest. Dermatol. 106:1996;168-175.
19. Napoli J.L. Retionid acid biosynthesis and metabolism. FASEB J. 10:1996;993-1001.
20. Siegenthaler G., Saurat J.H., Ponec M. Retinol and retinal metabolism. Relation to the state of differentiation of cultured human keratinocytes. Biochem. J. 268:1990;371-378.
21. Siegenthaler G. Retinoic acid formation from retinol and retinal metabolism in epidermal cells. Methods Enzymol. 189:1990;530-536.
22. Chatellard-Gruaz D., Randolph R.K., Hagens G., Saurat J.-H., Siegenthaler G. Differentiation of human epidermal keratinocytes is accompanied by increased expression of CRABP-II and increased cellular concentration of retinoic acids: retention of newly synthesized retinoic acids by CRABP-II. J. Lipid Res. 39:1998;1421-1429.
23. Kuell E.A., Kang S., Voorhees J.J. Retinoic acid isomers applied to human skin in vivo each induce a 4-hydroxylase that inactivates only trans retinoic acid. J. Invest. Dermatol. 106:1996;316-320.
24. White J.A., Guo Y.-D., Baetz K., Beckett-Jones B., Bonasoro J., Hsu K.E., Kilworth F.J., Jones G., Petkovich M. Identification of the retinoic acid-inducible all-trans-retinoic acid 4-hydroxylase. J. Biol. Chem. 271:1996;29922-29927.
25. White J.A., Beckett-Jones B., Guo Y.-D., Kilworth F.J., Bonasoro J., Jones G., Petkovich M. CDNA cloning of human retinoic acid-metabolizing enzyme (hP450RAI) identifies a novel family of cytochromes P450 (CPY26). J. Biol. Chem. 272:1997;18538-18541.
26. Abu-Abed S.S., Beckett B.R., Chiba H., Chithalen J.V., Jones G., Metzger D., Chambon P., Petkovich M. Mouse P450RAI (CPY26) expression and retinoic acid-inducible retinoic acid metabolism in F9 cells are regulated by retinoic acid receptor g and retinoid X receptor a. J. Biol. Chem. 273:1998;2409-2415.
27. R.C. Moon, R.G. Mehta, K.V.N. Rao, Retinoids and cancer in experimental animals, in: M.B. Sporn, A.B. Roberts, D.S. Goodman (Eds.), The Retinoids: Biology, Chemistry and Medicine, 2nd edn., Raven Press, New York, 1994, pp. 573-596.
28. W.K. Hong, L.M. Itri, Retinoids of human cancer, in: M.B. Sporn, A.B. Roberts, D.S. Goodman (Eds.), The Retinoids: Biology, Chemistry and Medicine, 2nd edn., Raven Press, New York, 1994, pp. 597-630.
29. Issing W.J., Struck R., Naumann A. Long-term follow up of larynx leukoplakia under treatment with retinyl palmitate. Head Neck. 18:1996;560-565.
30. W.J. Issing, R. Struck, A. Naumann, Positive impact of retinyl palmitate in leukoplakia of the larynx, Eur. Arch. Oto-Rhino-Laryngol. Suppl. (1997) 5105-5109.
31. Khuri P.R., Lippman S.M., Spitz M.R., Lotan R., Hong W.K. Molecular epidemiology of retinoid chemoprevention of head and neck cancers. J. Natl. Cancer Inst. 89:1997;199-211.
32. Guo X., Gudas L.J. Metabolism of all-trans-retinol in normal human cell strains and squamous cell carcinoma (SCC) lines from the oral cavity and skin: reduced esterification of retinol in SCC lines. Cancer Res. 58:1998;166-176.
33. Rheinwald J.G., Beckett M.A. Tumorogenic keratinocyte lines requiring anchorage and fibroblast support cultured from human squamous cell carcinoma. Cancer Res. 41:1981;1657-1663.
34. Wu Y.-J., Rheinwald J.G. A new 40 kD keratin filament protein made by some squamous cell carcinomas. Cell. 25:1981;627-635.
35. Rheinwald J.G., Green H. Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell. 6:1975;331-334.
36. Thacher S.M., Coe E.L., Rice R.H. Retinoid suppression of transglutaminase activity and envelope competence in cultured human epidermal carcinoma cells. Differentiation. 29:1985;82-87.
37. Agarwal C., Rork E.A., Boyce M., Howard J., Crish J., Hufeisen S., Eckert R.L. Retinoid dependent transcriptional suppression of cytokeratin gene expression in human epidermal squamous cell carcinoma cells. Differentiation. 52:1993;185-191.
38. Hu L., Crowe D.I., Rheinwald J.G., Chambon P., Gudas L.J. Abnormal expression of RARs and K19 by oral and epidermal squamous cell carcinoma. Cancer Res. 51:1991;3972-3981.
39. Barua A.B. Analysis of water soluble compounds: glucaronides. Methods Enzymol. 189:1990;136-145.
40. Markwell M.A., Haas S.M., Bieber L.L., Tolbert N.E. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal. Biochem. 87:1978;206-210.
41. Ross A.C. Separation and quantitation of retinyl esters and retinol by high-performance liquid chromatography. Methods Enzymol. 123:1986;68-74.
42. Herr F.M., MacDonald P.N., Ong D.E. Solubilization and partial characterization of lecithin retinol acyltransferase from rat liver. J. Nutr. Biochem. 2:1991;503-511.
43. 14C-labelled vitamin A alcohol and b-carotene in the rat. J. Biol. Chem. 240:1965;2835-2844.
44. Phillips M.A., Stewart B.E., Qin Q., Chakravarty R., Floyd E.E., Jetten A.M., Rice R.H. Primary structure of keratinocyte transglutaminase. Proc. Natl. Acad. Sci. USA. 87:1990;9333-9337.
45. J. Sambrook, E.F. Fritsch, T. Maniatis, Molecular Cloning. A laboratory Manual, 2nd edn., Cold Spring Harbor Laboratory Press, Plainview, NY, 1989.
46. Furr H.C. Reversed-phase high-performance liquid chromatography of retinyl esters. Methods Enzymol. 189:1990;85-94.
47. Helgerud P., Petersen L.B., Norum K.R. Acyl CoA:retinol acetyltransferase in at small intestine: its activity and some properties of the enzymatic reaction. J. Lipid Res. 23:1982;609-618.
48. Ross A.C. Retinol esterification by rat liver microsomes. Evidence for a fatty acyl coenzyme A:retinol transferase. J. Biol. Chem. 257:1982;2453-2459.
49. Cline P.R., Rice R.H. Modulation of involucrin and envelope competence in human keratinocytes by hydrocortisone, retinyl acetate and growth arrest. Cancer Res. 43:1983;3203-3207.
50. R.H. Rice, P.R. Cline, Mutually antagonistic effects of hydrocortisone and retinyl acetate on envelope competence in cultured malignant human keratinocytes, J. Invest. Dermatol. 81 (1983) 176S-178S1.
51. Vahlquist A., Andersson E., Coble B.I., Rollman O., Torma H. Increased concentrations of 3,4-didehydroretinol and retinoic acid-binding protein (CRABPII) in human squamous cell carcinoma and keratoacanthoma but not in basal cell carcinoma of the skin. J. Invest. Dermatol. 106:1996;1070-1074.
52. Berne B., Torma H., Staberg B., Mikkelsen S., Vahlquist A. Decreased retinyl ester concentrations in UV-induced murine squamous cell carcinomas. Acta Derm.-Venereol. 69:1989;503-508.
53. D.E. Ong, M.E. Newcomer, F. Chytil, Cellular retinoid-binding proteins, in: M.B. Sporn, A.B. Roberts, D.S. Goodman (Eds.), The Retinoids: Biology, Chemistry and Medicine, 2nd edn., Raven Press, New York, 1994, pp. 283-317.
54. Sundaresan P.R., De Luca L.M. Vitamin A contents of rat intestinal epithelium and jejunal mucinous adenocarcinoma. J. Natl. Cancer Inst. 58:1977;1643-1645.
55. Randolph R.K., Ross A.C. Regulation of retinol uptake and esterification in MCF-7 and HepG2 cells by exogenous fatty acids. J. Lipid Res. 32:1991;809-820.