A facile KF/Al2O3 mediated method for the synthesis of substituted oxazolidinones

Tetrahedron Letters

Volumn 40, Issue 36, 1999, Pages 6545-6547

  Blass, Benjamin E ^a   Drowns, Matthew ^a   Harris, Cheryl L ^a   Liu, Song ^a   Portlock, David E ^a  

^a PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXAZOLIDINONE DERIVATIVE; ALUMINUM DERIVATIVE; BROMIDE; ISOCYANATE; OXAZOLIDINONE DERIVATIVE; SULFONYL CHLORIDE; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CHEMICAL BINDING; CHEMICAL REACTION KINETICS; DRUG PURITY; REACTION ANALYSIS; SYNTHESIS;

EID: 0033520245     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(99)01310-6     Document Type: Article

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14. 2 and 161.4 mg (0.85 mmol) of p-toluenesulfonyl chloride is added. The reaction is stirred vigorously at room temperature for 24 h, filtered, and stripped of solvent to yield 241 mg (86%) of the desired product.