Synthesis of novel analogues of the delta opioid ligand SNC-80 using AlCl3-promoted aminolysis

Bioorganic and Medicinal Chemistry Letters

Volumn 9, Issue 9, 1999, Pages 1329-1334

  Barn, D R ^a   Bom, A ^a   Cottney, J ^a   Caulfield, W L ^a   Morphy, J R ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL] N,N DIETHYLBENZAMIDE; ALUMINUM CHLORIDE; CLOCINNAMOX; DELTA OPIATE RECEPTOR AGONIST; NALTRINDOLE;

ANIMAL EXPERIMENT; ANTINOCICEPTION; ARTICLE; BINDING AFFINITY; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; HUMAN; MOUSE; SUBCUTANEOUS DRUG ADMINISTRATION;

ALUMINUM COMPOUNDS; ANIMALS; BENZAMIDES; CHLORIDES; INHIBITORY CONCENTRATION 50; MICE; PIPERAZINES; RECEPTORS, OPIOID, DELTA;

EID: 0033519250     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00174-2     Document Type: Article

References (12)

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5. 3 in dichloromethane.
6. 4OH; 90 : 10 : 0.5]. Fractions containing products were evaporated to dryness.
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10. 50 values calculated.
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12. 50 values are calculated from results obtained in four animals and are expressed as mean values.