Synthesis of an array of amides by aluminium chloride assisted cleavage of resin-bound esters

Tetrahedron Letters

Volumn 37, Issue 18, 1996, Pages 3213-3216

  Barn, David R ^a   Morphy, J Richard ^a   Rees, David C ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE;

ARTICLE; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS; STEREOCHEMISTRY; TECHNIQUE;

EID: 0029918554     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4039(96)00498-4     Document Type: Article

References (12)

1. Terrett, N.K.; Gardner, M.; Gordon, D.W.; Kobylecki, R.J.; Steele, J. Tetrahedron 1995, 51, 8135-8173
2. Atherton, E.; Logan, C.J.; Sheppard, R.C. J. Chem. Soc., Perkin Trans. 1 1981, 538-546
3. DeGrado, W.F.; Kaiser, E.T. J. Org. Chem. 1980, 45, 1295-1300
4. Lobl, T.J.; Maggiora, L.L. J. Org. Chem. 1988, 53, 1979-1982
5. Ley, S.V.; Mynett, D.M.; Koot, W-J. Synlett, 1995, 1017-1020
6. Yazawa, H; Tanaka, K.; Kariyone, K. Tetrahedron Lett. 1974, 46, 3995-3996
7. Yamamoto, Y.; Yatagai, H.; Maruyama, K. J. Chem. Soc., Chem. Commun. 1980, 835-836
8. Gless, R.D. Synth. Commun. 1986, 16, 633-638
9. Basha, A.; Lipton, M.; Weinreb, S.M. Tetrahedron Lett. 1977, 48, 4171-4174
10. Wang W-B.; Roskamp, E.J. J.Org.Chem. 1992, 57, 6101-6103
11. 3) δ : 3.63 (t, 2H), 3.47 (t, 2H), 2.36 (m, 12H), 2.30 (s, 3H), 1.58 (m, 8H), 1.42 (m, 2H), 1.34 (m, 2H).
12. Look, G.C.; Holmes, C.P.; Chinn, J.P.; Gallop, M.A. J.Org.Chem. 1994, 59, 7588-7590