Adhesive but not lateral E-cadherin complexes require calcium and catenins for their formation

Journal of Cell Biology

Volumn 142, Issue 3, 1998, Pages 837-846

  Chitaev, Nikolai A ^a   Troyanovsky, Sergey M ^a,b  

^a WASHINGTON UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cadherins; Catenins; Epithelial cells; Intercellular adhesion; p120

Indexed keywords

ALPHA CATENIN; BETA CATENIN; CALCIUM ION; CATENIN; PLAKOGLOBIN; UVOMORULIN;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ARTICLE; CANCER CELL CULTURE; CELL ADHESION; CELL COMMUNICATION; COMPLEX FORMATION; DIMERIZATION; EPITHELIUM CELL; HUMAN; HUMAN CELL; KERATINOCYTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

ALPHA CATENIN; BETA CATENIN; CADHERINS; CALCIUM; CELL ADHESION; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DIMERIZATION; EPITHELIAL CELLS; HUMANS; TRANS-ACTIVATORS;

EID: 0031852523     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.142.3.837     Document Type: Article

References (46)

1. Birchmeier, W., and J. Behrens. 1994. Cadherin expression in carcinomas: role in formation of cell junctions and the prevention of invasiveness. Biochim. Biophys. Acta. 1198:11-26.
2. Blaschuk, O.W., R. Sullivan, S. David, and Y. Pouliot. 1990. Identification of a cadherin cell adhesion recognition sequence. Dev. Biol. 139:227-229.
3. Boukamp, P., R.T. Petrussevska, D. Breitkreutz, J. Hornung, A. Markham, and N.E. Fusenig. 1988. Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J. Cell Biol. 106:761-771.
4. Brieher, W.M., A.S. Yap, and B.M. Gumbiner. 1996. Lateral dimerization is required for the homophilic binding activity of C-cadherin. J. Cell Biol. 135: 487-496.
5. Bussemakers, M.J., A. van Bokhoven, S.G. Mees, R. Kemler, and J.A. Schalken. 1993. Molecular cloning and characterization of the human E-cadherin cDNA. Mol. Biol. Rep. 17:123-128.
6. 2+-dependent cell-cell adhesion. FEBS (Fed. Eur. Biochem. Soc.)Lett. 355:195-200.
7. Chitaev, N.A., R.E. Leube, R.B. Troyanovsky, L.G. Eshkind, W.W. Franke, and S.M. Troyanovsky. 1996. The binding of plakoglobin to desmosomal cadherins: patterns of binding sites and topogenic potential. J. Cell Biol. 133: 359-369.
8. 2+-dependent heterophilic interaction between desmosomal cadherins, desmoglein and desmocollin, contributes to cell-cell adhesion. J. Cell Biol. 138:193-201.
9. Chitaev, N.A., A.Z. Averbakh, R. Troyanovsky, and S.M. Troyanovsky. 1998. Molecular organization of the desmoglein-plakoglobin complex. J. Cell Sci. 111:1941-1949.
10. Citi, S. 1992. Protein kinase inhibitors prevent junction dissociation induced by low extracellular calcium in MDCK epithelial cells. J. Cell Biol. 117:169-178.
11. Citi, S., T. Volberg, A.D. Bershadsky, N. Denisenko, and B. Geiger. 1994. Cytoskeletal involvement in the modulation of cell-cell junctions by the protein kinase inhibitor H-7. J. Cell Sci. 107:683-692.
12. Edelman, G., B. Cunningham, and J.-P. Thiery. 1990. Morphoregulatory molecules. J. Wiley & Sons. New York. 648 pp.
13. Fujimori, T., and M. Takeichi. 1993. Disruption of epithelial cell-cell adhesion by exogenous expression of a mutated nonfunctional N-cadherin. Mol. Biol. Cell. 4:37-47.
14. Geiger, B., and O. Ayalon. 1992. Cadherins. Annu. Rev. Cell Biol. 8:307-332.
15. Gumbiner. G.M. 1996. Cell adhesion: the molecular basis of tissue architecture and morphogenesis. Cell. 84:345-357.
16. Hinck, L., I.S. Nathke, J. Papkoff, and W.J. Nelson. 1994. Dynamics of cadherin/catenin complex formation: Novel protein interactions and pathways of complex assembly. J. Cell Biol. 125:1327-1340.
17. Hubar, O., C. Bierkamp, and R. Kemler. 1996. Cadherins and catenins in development. Curr. Opin. Cell Biol. 8:685-691.
18. Hynes, R.O. 1992. Specificity of cell adhesion in development: the cadherin superfamily, Curr. Opin. Gen. Dev. 2:621-624.
19. Jou, T.-S., D.B. Stewart, J. Stappert, W.J. Nelson, and J.A. Marrs. 1995. Genetic and biochemical dissection of protein linkages in the cadherin-catenin complex. Proc. Natl. Acad. Sci. USA. 92:5067-5071.
20. Kartenbeck, J., E. Schmid, W.W. Franke, and B. Geiger. 1982. Different modes of internalization of proteins associated with adherens junctions and desmosomes: experimental separation of lateral contacts induces endocytosis of desmosomal plaque material. EMBO (Eur. Mol. Biol. Organ.) J. 1:725-732.
21. Kintner, C. 1992. Regulation of embryonic cell adhesion by the cadherin cytoplasmic domain. Cell. 69:225-236.
22. Klymkowsky, M., and B. Parr. 1995. The body language of cells: the intimate connection between cell adhesion and behavior. Cell. 83:5-8.
23. Knudsen, K.A., A. Peralta Soler, K.R. Johnson, and M.J. Wheelock. 1995. Interaction of α-actinin with the cadherin/catenin cell-cell adhesion complex via α-catenin. J. Cell Biol. 130:67-77.
24. Koch, A.W., S. Pokutta, A. Lustig, and J. Engel. 1997. Calcium binding and homoassociation of E-cadherin domains. Biochemistry. 36:7697-7705.
25. Laemmli, U.K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature. 227:680-687.
26. Maurer, P., E. Hohenester, and J. Engel. 1996. Extracellular calcium-binding proteins. Curr. Opin. Cell. Biol. 8:609-617.
27. Nagafuchi, A., and M. Takeichi. 1988. Cell binding function of E-cadherin is regulated by the cytoplasmic domain. EMBO (Eur. Mol. Biol. Organ.) J. 7:3679-3684.
28. Nagar, B., M. Overduin, M. Ikura, and J.M. Rini. 1996. Structural basis of calcium-induced E-cadherin rigidification and dimerization. Nature. 380:360-364.
29. Nelson, W.J., E.M. Shore, A.Z. Wang, and R.W.Hammerton. 1990. Identification of a membrane-cytoskeletal complex containing the cell adhesion molecule uvomorulin (E-cadherin). ankyrin, and fobrin in Madin-Darby canine kidney epithelial cells. J. Cell Biol. 110:349-357.
30. Nose, A., K. Tsuji, and M. Takeichi. 1990. Localization of specificity determining sites in cadherin cell adhesion molecules. Cell. 61:147-155.
31. Overduin, M., T.S. Harvey, S. Bagby, K.I. Tong, P. Yau, M. Takeichi, and M. Ikura. 1995. Solution structure of the epithelial cadherin domain responsible for selective cell adhesion. Science. 267:386-389.
32. Ozawa, M., H. Baribault, and R. Kemler. 1989. The cytoplasmic domain of the cell adhesion molecule uvomorulin associates with three independent proteins structurally related in different species. EMBO (Eur. Mol. Biol. Organ) J. 8:1711-1717.
33. 2+-binding site of uvomorulin abolish the adhesive function. Cell. 63: 1033-1038.
34. Ozawa, M., M. Ringwald, and R. Kemler. 1990b. Uvomorulin-catenin complex formation is regulated by a specific domain in the cytoplasmic region of the cell adhesion molecule. Proc. Natl. Acad. Sci. USA. 87:4246-4250.
35. Ozawa, M., and R. Kemler. 1992. Molecular organization of the uvomorulin-catenin complex. J. Cell Biol. 116:989-996.
36. Peifer, M. 1995. Cell adhesion and signal transduction: the Armadillo connection. Trends Cell Biol. 5:224-229.
37. Pokutta, S., K. Herrenknecht, R. Kemler, and J. Engel. 1994. Conformational changes of the recombinant extracellular domain of E-cadherin upon calcium binding. Eur. J. Biochem. 223:1019-1026.
38. cas associates with E-cadherin complexes. Mol. Cell Biol. 14:8333-8342.
39. Rimm, D.L., E.P. Koslov, P. Kebriaei, C.D. Cianci, and J.S. Morrow. 1995. Alpfa 1(E)-catenin is an actin-binding and -bundling protein mediating the attachment of F-actin to the membrane adhesion complex. Proc. Natl. Acad. Sci. USA. 92:8813-8817.
40. Shapiro, L., A.M. Fannon, P.D. Kwong, A. Thompson, M.S. Lehmann, G. Grubel, J-F. Legrand, J. Als-Neilsen, D.R. Colman, and W.A. Hendrickson. 1995. Structural basis of cell-cell adhesion by cadherins. Nature. 374:327-337.
41. Shibamoto, S., M. Hayakawa, K. Takeuchi, T. Hori, K. Miyazawa, N. Kitamura, K.R. Johnson, M.J. Weelock, N. Matsuyoshi, M. Takeichi, and F. Ito. 1995 Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexes. J. Cell Biol. 128:949-957.
42. Takeichi, M. 1991. Cadherin cell adhesion receptors as a morphogenetic regulators. Science. 251:1451-1455.
43. Takeichi, M. 1993. Cadherins in cancer: implications for invasion and metastasis. Curr. Opin. Cell Biol 5:806-811
44. Tomschy, A., C. Fauser, R. Landwehr, and J. Engel. 1996. Homophilic adhesion of E-cadherin occurs by a co-operative two-step interaction of N-terminal domains. EMBO (Eur. Mol. Biol. Organ.) J. 15:3507-3514.
45. Vasiliev, J.M., and I.M. Gelfand. 1981. Neoplastic and Normal Cells in Culture. Cambridge University Press, Cambridge, UK. 346 pp.
46. 2+ ions. J. Cell Biol. 102:1832-1842.