Expression of human GFRα-1 (GDNF receptor) at the neuromuscular junction and myelinated nerves

Neuroscience Letters

Volumn 269, Issue 1, 1999, Pages 55-57

  Hase, Asako ^a   Suzuki, Hidenori ^a,b,c   Arahata, Kiichi ^a   Akazawa, Chihiro ^a  

^a NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

^b NIPPON MEDICAL SCHOOL   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

GFR 1; Glial cell line derived neurotrophic factor; Glial cell line derived neurotrophic factor receptor alpha; Human; Immunohistochemistry; Neuromuscular junction; Reverse transcriptase polymerase chain reaction; Skeletal muscle

Indexed keywords

CELL RECEPTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR;

ARTICLE; CELL SURVIVAL; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MOTONEURON; MYELINATED NERVE; NEUROMUSCULAR SYNAPSE; PERIPHERAL NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN TRANSPORT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SKELETAL MUSCLE; SPINAL CORD VENTRAL HORN;

DROSOPHILA PROTEINS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR RECEPTORS; HUMANS; IMMUNOHISTOCHEMISTRY; MOTOR NEURONS; MYELIN SHEATH; NERVE GROWTH FACTORS; NERVE TISSUE PROTEINS; NEUROMUSCULAR JUNCTION; PERIPHERAL NERVES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-RET; RECEPTOR PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPINAL CORD;

EID: 0033516687     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(99)00419-X     Document Type: Article

References (13)

1. Akazawa C., Shigemoto R., Bessho Y., Nakanishi S., Mizuno N. Differential expression of five N-methyl-D-aspartate receptor subunit mRNAs in the cerebellum of developing and adult rats. J. Comp. Neurol. 347:1994;150-160.
2. Duberley R.M., Johnson I.P., Martin J.E., Anand P. RET-like immunostaining of spinal motoneurons in amyotrophic lateral sclerosis. Brain Res. 789:1998;351-354.
3. Durbec P., Marcos-Gutierrez C.V., Kilkenny C., Grigoriou M., Wartiowaara K., Suvanto P., Smith D., Ponder B., Costantini F., Saarma M., Sariola H., Pachnis V. GDNF signalling through the Ret receptor tyrosine kinase. Nature. 831:1996;789-793.
4. Henderson C.E., Phillips H.S., Pollock R.A., Davies A.M., Lemeulle C., Armanini M., Simpson L.C., Moffet B., Vandlen R.A., Koliatsos V.E., Rosenthal A. GDNF: a potent survival factor for motoneurons present in peripheral nerve and muscle. Science. 266:1994;1062-1064.
5. Jing S., Wen D., Yu Y., Holst P.L., Luo Y., Fang M., Tamir R., Antonio L., Hu Z. GDNF-induced activation of the Ret protein tyrosine kinase is mediated by GDNFR-α, a novel receptor for GDNF. Cell. 85:1996;1113-1124.
6. Oppenheim R.M. Neurotrophic survival molecules for motoneurons: an embarrassment of riches. Neuron. 17:1996;195-197.
7. Suzuki H., Hase A., Miyata Y., Arahata K., Akazawa C. Prominent expression of glial cell line-derived neurotrophic factor in human skeletal muscle. J. Comp. Neurol. 402:1998;303-312.
8. Suzuki H., Hase A., Kim B.Y., Miyata Y., Nonaka I., Arahata K., Akazawa C. Up-regulation of glial cell line-derived neurotrophic factor (GDNF) expression in regenerating muscle fibers in neuromuscular diseases. Neurosci. Lett. 257:1998;165-167.
9. Treanor J.J.S., Goodman L., de Sauvage F., Stone D.M., Poulsen K.T., Beck C.D., Gray C., Armanini M.P., Pollock R.A., Hefti F., Phillips H.S., Goddard A., Moore M.W., Buj-Bello A., Davis A.M., Asai N., Takahashi M., Vandlen R., Henderson C.E., Rosenthal A. Characterization of a multicomponent receptor for GDNF. Nature. 382:1996;80-83.
10. Trupp M., Rydén M., Jörnvall H., Funakoshi H., Timmusk T., Arenas E., Ibáñez C.F. Peripheral expression and biological activities of GDNF, a new neurotrophic factor for avian and mammalian peripheral neurons. J. Cell Biol. 130:1995;137-148.
11. Trupp M., Arenas E., Fainzilber M., Nilsson A.S., Sieber B.A., Grigoriou M., Kilkenny C., Salazar-Grueso E., Pachnis V., Arumäe U., Sariola H., Saarma M., Ibáñez C.F. Functional receptor for GDNF encoded by the c-ret proto-oncogene. Nature. 381:1996;785-789.
12. Yamamoto M., Mitsuma N., Ito Y., Hattori N., Nagamatsu M., Li M., Mitsuma T., Sobue G. Expression of glial cell line-derived neurotrophic factor and GDNFR-α mRNAs in human peripheral neuropathies. Brain Res. 809:1998;175-181.
13. Yan Q., Matheson C., Lopez O.T. In vivo neurotrophic effects of GDNF on neonatal and adult facal motor neurons. Nature. 373:1995;341-344.