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Volumn 121, Issue 21, 1999, Pages 5099-5100

Catalytic asymmetric aziridination with a chiral VAPOL-boron Lewis acid

Author keywords

[No Author keywords available]

Indexed keywords

AZIRIDINE DERIVATIVE; BORONIC ACID DERIVATIVE; COPPER; RHODIUM;

EID: 0033516315     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja9905187     Document Type: Article
Times cited : (177)

References (36)
  • 25
    • 0029928540 scopus 로고    scopus 로고
    • For other approaches, see: (a) Aires-de-Sousa, J.; Lobo, A. M.; Probhakar, S. Tetrahedron Lett. 1996, 37, 3183. (b) Verstappen, M. M. H.; Ariaans, G. J. A.; Zwanenburg, B. J. Am. Chem. Soc. 1996, 118, 8491.
    • (1996) Tetrahedron Lett. , vol.37 , pp. 3183
    • Aires-de-Sousa, J.1    Lobo, A.M.2    Probhakar, S.3
  • 31
    • 0345695693 scopus 로고    scopus 로고
    • note
    • The same selectivity is observed with a catalyst prepared with 1.0 equiv of borane-THF complex, but catalyst formation requires longer periods of time.
  • 32
    • 0345695694 scopus 로고    scopus 로고
    • note
    • 13 by reaction of benzhydrylamine with 1.0 equiv of aldehyde in methylene chloride at rt in the presence of anhydrous magnesium sulfate. After filtration, the solvent is removed and the imine purifed by crystallization from ethanol with the exception of 8h which is an oil and was used without purification.
  • 33
    • 0344401166 scopus 로고    scopus 로고
    • note
    • Imines derived from pivaldehyde and 1-naphthylaldehyde would not undergo reaction under the conditions in Table 2.
  • 35
    • 0344832680 scopus 로고    scopus 로고
    • note
    • The enantiomeric excess of the aziridine 10a can be improved from 97.0 to 99.2% with one crystallization from methylene chloride and pentane.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.