Voltage-insensitive Ca2+ channels and Ca2+/calmodulin-dependent protein kinases propagate signals from endothelin-1 receptors to the c-fos promoter

Molecular and Cellular Biology

Volumn 16, Issue 10, 1996, Pages 5915-5923

  Wang, Yuan ^a   Simonson, Michael S ^a,b  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM ION; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; PROTEIN C FOS; PROTEIN KINASE (CALCIUM,CALMODULIN); PROTEIN KINASE INHIBITOR; BENZYLAMINE DERIVATIVE; CALCIUM; ENDOTHELIN A RECEPTOR; ENZYME INHIBITOR; LUCIFERASE; MESSENGER RNA; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; PRIMER DNA; RECOMBINANT PROTEIN; SULFONAMIDE;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CELL DIFFERENTIATION; CELL GROWTH; GENE EXPRESSION REGULATION; MALE; MESANGIUM CELL; NONHUMAN; ONCOGENE C FOS; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CELL CULTURE; CELL NUCLEUS; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; KINETICS; MESANGIUM; METABOLISM; NUCLEOTIDE SEQUENCE; ONCOGENE; PHYSIOLOGY; POINT MUTATION; POLYMERASE CHAIN REACTION; PROMOTER REGION; REPORTER GENE; SITE DIRECTED MUTAGENESIS; SPRAGUE DAWLEY RAT;

ANIMALIA;

ANIMALS; BASE SEQUENCE; BENZYLAMINES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CALCIUM; CALCIUM CHANNELS; CELL NUCLEUS; CELLS, CULTURED; DNA PRIMERS; ENDOTHELIN-1; ENZYME INHIBITORS; GENES, FOS; GENES, REPORTER; GLOMERULAR MESANGIUM; KINETICS; LUCIFERASES; MALE; MUTAGENESIS, SITE-DIRECTED; POINT MUTATION; POLYMERASE CHAIN REACTION; PROMOTER REGIONS (GENETICS); PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN; RECOMBINANT PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; SULFONAMIDES; TRANSCRIPTION, GENETIC; TRANSFECTION;

EID: 0029662008     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.16.10.5915     Document Type: Article

References (60)

1. Bading, H., D. D. Ginty, and M. E. Greenberg. 1993. Regulation of gene expression in hippocampal neurons by distinct calcium signaling pathways. Science 260:181-186.
2. Baynash, A. G., K. Hosoda, A. Giaid, J. A. Richardson, N. Emoto, R. E. Hammer, and M. Yanagisawa. 1994. Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons. Cell 79:1277-1285.
3. Benigni, A., C. Zoja, D. Corna, S. Orisio, L. Longaretti, T. Bertani, and G. Remuzzi. 1993. A specific endothelin subtype A receptor antagonist protects against functional and structural injury in a rat model of renal disease progression. Kidney Int. 44:440-444.
4. Berkowitz, L. A., K. T. Riabowol, and M. Z. Gilman. 1989. Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter. Mol. Cell. Biol. 9:4272-4281.
5. Chant, J., and L. Stowers. 1995. GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more. Cell 81:1-4.
6. Curran, T., M. B. Gordon, K. L. Rubino, and L. C. Sambucetti. 1987. Isolation and characterization of the c-fos(rat) cDNA and analysis of post-translational modification in vitro. Oncogene 2:79-84.
7. Douglas, S. A., C. Louden, L. M. Vickery-Clark, B. L. Storer, T. Hart, G. Z. Feuerstein, J. D. Elliott, and E. H. Ohlstein. 1994. A role for endogenous endothelin-1 in neointimal formation after rat carotid artery balloon angioplasty. Circ. Res. 75:190-197.
8. Fisch, T. M., R. Prywes, and R. G. Roeder. 1987. c-fos sequences necessary for basal expression and induction by epidermal growth factor, 12-O-tetradecanoyl phorbol-13-acetate, and the calcium ionophore. Mol. Cell. Biol. 7:3490-3502.
9. Fisch, T. M., R. Prywes, M. C. Simon, and R. G. Roeder. 1989. Multiple sequence elements in the c-fos promoter mediate induction by cAMP. Genes Dev. 3:198-211.
10. Ghosh, A., and M. E. Greenberg. 1995. Calcium signaling in neurons: molecular mechansisms and cellular consequences. Science 268:239-247.
11. Giad, A., M. Yanagisawa, D. Langleben, R. P. Michel, R. Levy, H. Shennib, S. Kimura, T. Masaki, W. P. Duguid, and D. J. Stewart. 1993. Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N. Engl. J. Med. 328:1732-1739.
12. Gilman, M. Z. 1988. The c-fos serum response element responds to protein kinase C-dependent and -independent signals hut not to cyclic AMP. Genes Dev. 2:394-402.
13. Gilman, M. Z., R. N. Wilson, and R. A. Weinberg. 1986. Multiple protein-binding sites in the 5′-flanking region regulate c-fos expression. Mol. Cell. Biol. 6:4305-4316.
14. Goto, K., Y. Kasuya, N. Matsuki, Y. Takuwa, H. Kurihara, T. Ishikawa, S. Kiumura, M. Yanagisawa, and T. Masaki. 1989. Endothelin activates the dihydropyridine-sensitive, voltage-dependent Ca2+ channel in vascular smooth muscle. Proc. Natl. Acad. Sci. USA 86:3915-3918.
15. Graham, R., and M. Z. Gilman. 1991. Distinct protein targets for signals acting at the c-fos scrum response clement. Science 251:189-192.
16. Grynkiewicz, G., M. Poenie, and R. Y. Tsien. 1985. A generation of Ca2+ indicators with greatly improved fluorescence properties. J Biol. Chem. 260:3440-3450.
17. Herman, W. H., and M. S. Simonson. 1995. Nuclear signaling by endothelin-1: a Ras pathway for activation of the c-fos serum response element. J. Biol. Chem. 270:11654-11661.
18. Hill, C. S., and R. Treisman. 1995. Differential activation of c-fos promoter elements by serum, lysophosphatidic acid, G proteins and polypeptide growth factors. EMBO J. 14:5037-5047.
19. Hill, C. S., J. Wynne, and R. Treisman. 1994. Serum-regulated transcription by serum response factor (SRF): a novel role for the DNA binding domain. EMBO J. 13:5421-5432.
20. Hill, S. H., J. Wynne, and R. Treisman. 1995. The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF. Cell 81:1159-1170.
21. Hosoda, K., R. E. Hammer, J. A. Richardson, A. G. Baynash, J. C. Cheung, A. Giaid, and M. Yanagisawa. 1994. Targeted and natural (Piebald-Lethal) mutations of endothelin-B receptor gene produce megacolon associated with spotted coat color in mice. Cell 79:1267-1276.
22. Huang, S., M. S. Simonson, and M. J. Dunn. 1993. Manidipine inhibits endothelin-1-induced [Ca2+]i signaling, but potentiates endothelin's effect of c-fos and c-jun induction in vascular smooth muscle and glomerular mesangial cells. Am. Heart J. 125:589-597.
23. Khosravi-Far, R., P. A. Solski, G. J. Clark, M. S. Kinch, and C. J. Der. 1995. Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation. Mol. Cell. Biol. 15:6443-6453.
24. Kurihara, Y., H. Kurihara, H. Oda, K. Maemura, R. Nagai, T. Ishikawa, and Y. Yazaki. 1995. Aortic arch malformations and ventricular septal defect in mice deficient in endothelin-1. J. Clin. Invest. 96:293-300.
25. Kurihara, Y., H. Kurihara, H. Suzuki, T. Kodama, K. Maemura, R. Nagai, H. Oda, T. Kuwaki, W.-H. Cao, N. Kamada, K. Jishage, Y. Ouchi, S. Azuma, Y. Toyoda, T. Ishikawa, M. Kumada, and Y. Yazaki. 1994. Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1. Nature (London) 368;703-710.
26. Lee, G., and M. Gilman. 1994. Dual modes of control of c-fos mRNA induction by intracellular calcium in T cells. Mol. Cell. Biol. 14:4579-4587.
27. Lerman, A., B. S. Edwards, J. W. Hallett, D. M. Heublein, S. M. Sandberg, and J. C. Burnett. 1991. Circulating and tissue endothelin immunoreactivity in advanced atherosclerosis. N. Engl. J. Med. 325:997-1001.
28. Levin, E. R. 1995. Endothelins. N. Engl. J. Med 333:356-363.
29. 2+/calmodulin-dependent protein kinase II inhibitor KN-93. Biochem. Biophys. Res. Commun. 195:608-615.
30. Masaki, T. 1993. Endothelins: homeostatic and compensatory actions in the circulatory and endocrine systems. Endocr. Rev. 14:256-268.
31. Matthews, R. P., C. R. Guthrie, L. M. Wailes, X. Zhao, A. K. Means, and G. S. McKnight. 1994. Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Mol. Cell. Biol. 14:6107-6116.
32. Merritt, J. E., W. P. Armstrong, C. D. Benham, T. J. Hallam, R. Jacob, A. Jaxa-Chamiec, B. K. Leigh, S. A. McCarthy, K. E. Moores, and T. J. Rink. 1990. SK&F 96365, a novel inhibitor of receptor-mediated calcium entry. Biochem. J. 271:515-522.
33. 2+/calmodulin-dependent kinase. Mol. Cell. Biol. 15:3672-3684.
34. Muldoon, L. L., D. Pribnow, K. D. Roland, and B. E. Magun. 1990. Endothelin-1 stimulates DNA synthesis and anchorage-independent growth of rat-1 fibroblasts through a protein kinase C-dependent mechanism. Cell Regul. 1:379-390.
35. Naitoh, T., T. Toyooka, and T. Sugimoto. 1990. An endogenous Ca2+ channel agonist, endothelin-1, does not directly activate partially purified dihydropyridine-sensitive Ca2+ channel from cardiac muscle in a reconstituted system. Biochem. Biophys. Res. Commun. 171:1205-1210.
36. Olson, M. F., A. Ashworth, and A. Hall. 1995. An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through GI. Science 269:1270-1272.
37. Pribnow, D., L. L. Muldoon, M. Fajardo, L. Theodor, L. S. Chen, and B. E. Magun. 1992. Endothelin induces transcription of fos/jun family genes: a prominent role for calcium ion. Mol. Endocrinol. 6:1003-1012.
38. Robertson, L. M., T. K. Kerppola, M. Vendrell, C. Bocchiaro, J. I. Morgan, and T. Curran. 1995. Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements. Neuron 14:241-252.
39. Rosen, L. B., D. D. Ginty, M. J. Weber, and M. E. Greenberg. 1994. Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras. Neuron 12:1207-1221.
40. Santoro, I. M., and K. Walsh. 1991. Natural and synthetic DNA elements with the CArG motif differ in expression and protein-binding properties. Mol. Cell. Biol. 11:6296-6305.
41. Sheng, M., G. McFadden, and M. E. Greenberg. 1990. Membrane depolarization and calcium induce c-fos transcription via phosphorylation of transcription factor CREB. Neuron 4:571-582.
42. Simonson, M. S. 1993. Endothelins: multifunctional renal peptides. Physiol. Rev. 73:375-411.
43. Simonson, M. S. 1994. Endothelin peptides and compensatory growth of renal cells. Curr. Opin. Nephrol. Hypertens. 3:73-85.
44. 43a. Simonson, M. S., et al. Unpublished data.
45. Simonson, M. S., and M. J. Dunn. 1990. Cellular signaling by peptides of the endothelin gene family. FASEB J. 4:2989-3000.
46. Simonson, M. S., and M. J. Dunn. 1990. Eicosanoid biochemistry in cultured glomerular mesangial cells. Methods Enzymol. 187:544-553.
47. Simonson, M. S., and M. J. Dunn. 1991. Ca2+ signaling by distinct endothelin peptides in glomerular mesangial cells. Exp. Cell Res. 192:148-156.
48. c-src. J. Biol. Chem. 268:9347-9357.
49. Simonson, M. S., and A. Rooney. 1994. Characterization of endothelin receptors in mesangial cells: evidence for two functionally distinct endothelin binding sites. Mol. Pharmacol. 46:41-50.
50. Simonson, M. S., Y. Wang, and W. H. Herman. 1996. Nuclear signaling by endothelin-1 requires Src protein tyrosine kinases. J. Biol. Chem. 271:77-82.
51. Simonson, M. S., Y. Wang, and W. H. Herman. 1996. Ca2+ channels mediate protein tyrosine kinase activation by endothelin-1. Am. J. Physiol. 270:F790-F797.
52. Simonson, M. S., S. Wann, P. Mene', G. Dubyak, M. Kester, Y. Nakazato, J. R. Sedor, and M. J. Dunn. 1989. Endothelin stimulates phospholipase C, Na+/H+ exchange, c-fos expression, and mitogenesis in rat mesangial cells. J. Clin. Invest. 83:708-712.
53. Simpson, A. W., and C. C. Ashley. 1989. Endothelin evoked Ca2+ transients and oscillations in A10 vascular smooth muscle cells. Biochem. Biophys. Res. Commun. 163:1223-1229.
54. Sun, P., H. Enslen, P. S. Myung, and R. A. Maurer. 1994. Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity. Genes Dev. 8:2527-2539.
55. Tanaka, M., and W. Herr. 1990. Differential transcriptional activation by Oct-1 and Oct-2: independent activation domains induce Oct-2 phosphorylation. Cell 60:375-386.
56. Yamashita, J.-I., M. Ogawa, H. Egami, S. Matsuo, H. Kiyohara, K. Inada, S.-I. Yamashita, and S. Fujita. 1992. Abundant expression of immunoreactive endothelin 1 in mammary phyllodes tumor: possible paracrine role of endothelin-1 in the growth of stromal cells in phyllodes tumor. Cancer Res. 52:4046-4049.
57. Yanagisawa, M. 1994. The endothelin system: a new target for therapeutic intervention. Circulation 89:1320-1322.
58. Yanagisawa, M., H. Kurihara, S. Kimura, Y. Tombe, M. Kobayashi, Y. Mitsui, Y. Yazaki, K. Goto, and T. Masaki. 1988. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature (London) 332:411-415.
59. Zhao, Y., M. Sudol, H. Hanafusa, and J. Krueger. 1992. Increased tyrosine kinase activity of c-Src during calcium-induced keratinocyte differentiation. Proc. Natl. Acad. Sci. USA 89:8298-8302.
60. 2+ levels. Mol. Cell. Biol. 13:7507-7514.