Gender difference in baroreflex-mediated bradycardia in young rats: Role of cardiac sympathetic and parasympathetic components

Canadian Journal of Physiology and Pharmacology

Volumn 77, Issue 5, 1999, Pages 358-366

  Abdel Rahman, Abdel A ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Baroreflex sensitivity; Conscious rats; Gender difference; Vagal outflow

Indexed keywords

ATROPINE METHYL BROMIDE; MUSCARINIC RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; BRADYCARDIA; CONTROLLED STUDY; EVOKED RESPONSE; HEART RATE; MEAN ARTERIAL PRESSURE; NONHUMAN; PRESSOR RESPONSE; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; SEX DIFFERENCE; SYMPATHETIC NERVE; SYMPATHETIC TONE; VAGUS NERVE STIMULATION; VASCULAR RESISTANCE;

EID: 0033506948     PISSN: 00084212     EISSN: None     Source Type: Journal    
DOI: 10.1139/y99-028     Document Type: Article

References (33)

1. Abdel-Rahman, A.R.A., Russ, R., Strickland, J.A., and Wooles, W.R. 1987. Acute effects of ethanol on baroreceptor reflex control of heart rate and on pressor and depressor responsiveness in rats. Can. J. Physiol. Pharmacol. 65: 834-841.
2. Abdel-Rahman, A.R.A., Merrill, R.H., and Wooles, W.R. 1994. Gender-related differences in the baroreceptor reflex control of heart rate in normotensive humans. J. Appl. Physiol. 77(2): 606-613.
3. Bedran-de-Castro, M.T.B., and Bedran-de-Castro, J.C. 1992. Sex-related differences in cardiovascular responses to common carotid occlusion in conscious rats. Braz. J. Med. Biol. Res. 25: 951-955.
4. Bunag, R.D., and Davidow, L.W. 1996. Aging impairs heart rate reflexes earlier in female than in male Sprague Dawley rats. Neurobiol. Aging, 17: 87-93.
5. Bunag, R.D., Walaszek, E.J., and Mueting, N. 1975. Sex differences in reflex tachycardia induced by hypotensive drugs in unanesthetized rats. Am. J. Physiol. 229(3): 652-656.
6. Chen, C.-Y., and DiCarlo, S.E. 1996. Daily exercise and gender influence arterial baroreflex regulation of heart rate and nerve activity. Am. J. Physiol. 271: H1840-H1848.
7. Coleman, T.G. 1980. Arterial baroreflex control of heart rate in the conscious rat. Am. J. Physiol. 238: H515-H520.
8. Crofton, J.T., Share, L., and Brooks, D.P. 1988. Pressor responsiveness to and secretion of vasopressin during the estrus cycle. Am. J. Physiol. 255: R1041-R1048.
9. Du, X.-J., Dart, A.M., and Riemersma, R.A. 1994. Sex difference in the parasympathetic nerve control of rat heart. Clin. Exp. Pharmacol. Physiol. 21: 485-493.
10. El-Mas, M.M., and Abdel-Rahman, A.A. 1997. Contrasting effects of urethane, ketamine, and thiopental anesthesia on ethanol-clonidine hemodynamic interaction. Alcohol. Clin. Exp. Res. 21: 19-27.
11. El-Mas, M.M., and Abdel-Rahman, A.A. 1998a. Estrogen enhances baroreflex control of heart rate in conscious ovariectomized rats. Can. J. Physiol. Pharmacol. 76: 381-386.
12. El-Mas, M.M., and Abdel-Rahman, A.A. 1998b. Ovariectomy abolishes ethanol-induced impairment of baroreflex control of heart rate in conscious rats. Eur. J. Pharmacol. 349: 253-261.
13. Girdler, S.S., Turner, I.R., Sherwood, A., and Light, K.C. 1990. Gender differences in blood pressure control during a variety of behavioral stressors. Psychosom. Med. 52: 571-591.
14. Guo, G.B., and Abboud, F.M. 1984. Angiotensin H attenuates baroreflex control of heart rate and sympathetic activity. Am. J. Physiol. 246: H80-H89.
15. He, X.-R., Wang, W., Crofton, J.T., and Share, L. 1998. Effects of 17β-estradiol on sympathetic activity and pressor response to phenylephrine in ovariectomized rats. Am. J. Physiol. 275: R1202-R1208.
16. Huikuri, H.V., Pikkujamsa, S.M., Airaksinen, K.E.J., Ikaheimo, M.J., Rantala, A.O., Kauma, H., Lilja, M., and Kesaniemi, A. 1996. Sex-related differences in autonomic modulation of heart rate in middle-aged subjects. Circulation, 94: 122-125.
17. Kollai, M., and Koizumi, K. 1989. Cardiac vagal and sympathetic nerve responses to baroreceptor stimulation in the dog. Pfluegers Arch. 413: 365-371.
18. Kollai, M., Jokkel, G., Bonyhay, I., Tomesanyi, I., and Naszlady, A. 1994. Relation between baroreflex sensitivity and cardiac vagal tone in humans. Am. J. Physiol. 266: H21-H27.
19. Korner, P.I., Shaw, J., West, M.I., and Oliver, J.R. 1972. Central nervous system control of baroreceptor reflexes in the rabbit. Circ. Res. 31: 637-652.
20. Korner, P.I., West, M.J., Shaw, J.S., and Uther, I.B. 1974. Steady-state properties of the baroreceptor - heart rate reflex in essential hypertension in man. Clin. Exp. Pharmacol. Physiol. 1: 65-76.
21. Montgomery, L.D., Kirk, P.J., Payne, P.A., Gerber, R.L., Newton, S.D., and Williams, B.A. 1977. Cardiovascular responses of men and women to lower body negative pressure. Aviat. Space Environ. Med. 48: 138-145.
22. Moore, K.L., and Newton, K. 1986. Orthostatic heart rates and blood pressure in healthy young men and women. Heart Lung, 15: 611-617.
23. Masilamani, S., and Heesch, C.M. 1997. Effects of pregnancy and progesterone metabolites on arterial baroreflex in conscious rats. Am. J. Physiol. 272: R924-R934.
24. Nuty, A.M., Segar, J.L., Holley, A.T., O'Mara, M.S., Chapleau, M.W., and Robillard, J.E. 1996. Arginine vasopressin modulation of arterial baroreflex responses in fetal and newborn sheep. Am. J. Physiol. 271: R1648-R1663.
25. Schohdorf, R., and Low, P.A. 1992. Gender related differences in the cardiovascular responses to upright tilt in normal subjects. Clin. Auton. Res. 2: 183-187.
26. Schvartz, E., and Meyerstein, N. 1970. Tilt tolerance of young men and young women. Aerospace Med. 41: 253-255.
27. Smyth, H.S., Sleight, P., and Pickering, G.W. 1969. Reflex regulation of arterial pressure during sleep in man: a quantitative method of assessing baroreflex sensitivity. Circ. Res. 24: 109-121.
28. Sullebarger, J.T., Liang, C.-S., Woolf, P.D., Willick, A.E., and Richeson, J.F. 1990. Comparison of phenylephrine bolus and infusion methods in baroreflex measurements. J. Appl. Physiol. 69: 962-967.
29. Walker, B.R., and Russ, R.D. 1994. Oxytocin augments baroreflex bradycardia in conscious rats. Peptides, 15: 907-912.
30. Wang, Y.-X., Crofton, J.T., and Share, L. 1997. Sex difference in the cardiovascular and renal actions of vasopressin in conscious rats. Am. J. Physiol. 272: R370-R376.
31. Weinstock, K.M., and Borosh, M. 1993. Low baroreflex sensitivity predisposes to salt sensitive hypertension in the rabbit. Am. J. Physiol. 264: H505-H511.
32. Weinstock, M., and Rosin, A.J. 1984. Relative contribution of vagal and cardiac sympathetic nerves to the reflex bradycardia induced by a pressor stimulus in the conscious rabbit: comparison of 'steady state' and 'ramp' methods. Clin. Exp. Pharmacol. Physiol. 11: 133-141.
33. Zhang, X., Abdel-Rahman, A.R.A., and Wooles, W.R. 1990. Selective sensitization by L-glutamate of baroreflex-mediated bradycardia following microinjection into the rostral ventrolateral medulla. Brain Res. 520: 141-150. 367