The effect of myo-inositol on ethanol-induced metabolic changes and insulin concentration in the rat

Archives of Physiology and Biochemistry

Volumn 107, Issue 4, 1999, Pages 334-337

  Szkudelski, T ^a   Kandulska, K ^a  

^a POZNA UNIVERSITY OF LIFE SCIENCES   (Poland)

Author keywords

Ethanol; Glycogen; Insulin; Lipids; Liver; Myo inositol

Indexed keywords

INOSITOL;

ALCOHOL CONSUMPTION; ALCOHOL LIVER CIRRHOSIS; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; GLYCOGEN METABOLISM; INSULIN BLOOD LEVEL; MALE; NONHUMAN; RAT; SIGNAL TRANSDUCTION; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 0033506089     PISSN: 13813455     EISSN: None     Source Type: Journal    
DOI: 10.1076/13813455199908107041qft334     Document Type: Article

References (30)

1. Allison JH, Cicero TJ (1980): Alcohol acutely depresses myo-inositol 1-phosphate levels in the male rat cerebral cortex. J Pharmacol Exp Ther 213: 24-27.
2. Andersen DB, Holub BJ (1980): Myo-inositol-responsive liver lipid acumulation in the rat. J Nutr 110: 488-495.
3. Baten A, Ullah A, Tomazic VJ, Shamsuddin AM (1989): Inositol-phosphate-induced enhancement of natural killer cell activity correlates with tumor suppression. Carcinogenesis 10: 1595-1598.
4. Beach DC, Flick PK (1982): Early effect of myo-inositol deficiency on fatty acid synthetic enzymes of rat liver. Biochim Biophys Acta 711: 452-459.
5. Bernal CA, Vazquez JA, Adibi SA (1992): Liver triglyceride concentration and body protein metabolism in ethanol-treated rats: effect of energy and nutrient supplementation. Gastrenterology 103: 289-295.
6. Carrasco MP, Segovia JL, Marco C (1998): Incorporation of exogenous precursors into neutral lipids and phospholipids in rat hepatocytes: effect of ethanol in vitro. Biochem Pharmacol 56: 1639-1644.
7. Dorrestijn J, van Bussel FJ, Maassen JA, Gomes de Mequita DS (1999): Early steps in insulin action. Arch Physiol Biochem 106: 269-289.
8. Folch J, Lees M, Sloane GSH (1975): A simple method of the isolation and purification of total lipids from animal tissues. J Biol Chem 226: 497-509.
9. Foster LB, Dunn RT (1973): Stable reagents for determination of serum triglycerides by a colorimetric Hatzsch condensation method. Clin Chem 19: 338-340.
10. Gonzales RA, Crews FT (1991): Chronic ethanol inhibits receptor-stimulated phosphoinositide hydrolysis in rat liver slices. Alcohol 8: 131-136.
11. Grunnet N, Kondrup J, Dich J (1987): Ethanol-induced accumulation of triacylglycerol in cultured hepatocytes: dependency on ethanol metabolism. Alcohol Alcohol 1: 257-261.
12. Khandelwal M, Reece EA, Wu YK, Borenstein M (1998): Dietary myo-inositol therapy in hyperglycemia-induced embryopathy. Teratology 57: 79-84.
13. Klimes I, Mitkova A, Gasperikova D, Ukropec J, Liska B, Bohov B, Stanek J, Sebokava E (1999): The effects of the new oral hypoclycemic agent A-4166 on glucose turnover in the high fat diet-induced and/or in the hereditary insulin resistance of rats. Arch Physiol Biochem 106: 325-332.
14. Paulet G, Dagorne D, Thomas S, Roncin G, Lessard Y (1977): Development of liver glycogen reserves in rats subjected to chronic alcoholic intoxication. C R Seances Soc Biol Fil 171: 228-232.
15. Reddi AS, Jyothirmayi GN, DeAngelis B, Frank O, Baker H (1991): Effect of short-and long-term diabetes on carnitine and myo-inositol in rats. Comp Biochem Physiol A 98: 39-42.
16. Reece EA, Khandelwal M, Wu YK, Borenstein M (1997): Dietary intake of myo-inositol and neural tube defects in offspring of diabetic rats. Am J Obstet Gynecol 176: 536-539.
17. Richmond W (1973): Preparation and properties of a cholesterol oxidase from Nocardia sp. and its application to the enzymatic assay of total cholesterol in serum. Clin Chem 19: 1350-1356.
18. Sakamoto K, Vucenik I, Shamsuddin AM (1993): [3H]phytic acid (inositol hexaphosphate) is absorbed and distributed to various tissues in rats. J Nutr 123: 713-720.
19. Sener A, Ramirez R, Malaisse WJ; (1992): A sensitive radioisotopic assay of myo-inositol: its application to rat pancreatic islets. Biochem Med Metab Biol 47: 116-123.
20. Sigal SH, Yandrasitz JR, Berry GT (1993): Kinetic evidence for compartmentalization of myo-inositol in hepatocytes. Metabolism 42: 395-401.
21. Sima AA, Dunlap JA, Davidson EP, Wiese TJ, Lightle RL, Greene DA, Yorek MA (1997): Supplemental myo-inositol prevents L-fructose-induced diabetic neuropathy. Diabetes 46: 301-306.
22. Singh SP, Patel DG Snyder AK (1980): Ethanol inhibition of insulin secretion by perifused rat islets. Acta Endocrinol 93: 61-66.
23. Szkudelski T, Chichlowska J, Kliber A (1999): Myoinositol augments insulin release from perfused rat pancreas. J Anim Feed Sci 8: 107-113.
24. Venkatesan S, Ward RJ, Peters TJ (1988): Effect of chronic ethanol feeding on the hepatic secretion of very-low-density lipoproteins. Biochim Biophys Acta 960: 61-66.
25. Vucenik I, Yang G, Shamsuddin AM (1995): Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer. Carcinogenesis 16: 1055-1058.
26. Winston GW, Reitz RC (1984): Effects of chronic ethanol ingestion on male and female rat liver glycogen phosphorylase phosphatase. Alcohol Clin Exp Res 8: 277-282.
27. Xia M, Laychock SG (1993): Insulin secretion, myo-inositol transport, and Na(+)-K(+)-ATP-ase in glucose-desenitized rat islets. Diabetes 42: 1392-1400.
28. Xiang H, Heyliger CE, McNeill JH (1988): Effect of myoinositol and T3 on myocardial lipids and cardiac function in streptozotocin-induced diabetic rats. Diabetes 37: 1542-1548.
29. Yu BY, Cronholm T (1997): Coupling of ethanol metabolism to lipid biosynthesis: labelling of glycerol moieties of sn-glycerol-3-phosphate, a phosphatidic acid and a phosphatidylcholine in liver of rats given [1,1-2H2]ethanol. Biochim Biophys Acta 1344: 165-170.
30. Zhang BH, Horsfield BP, Farrell GC (1996): Chronic ethanol administration to rats decreases receptor-operated mobilization of intracellular ionic calcium in cultured hepatocytes and inhibits 1,4,5-inositol triphosphate production: relevance to impaired liver regeneration. J Clin Invest 98: 1237-1244.