Supplemental myo-inositol prevents L-fucose-induced diabetic neuropathy

Diabetes

Volumn 46, Issue 2, 1997, Pages 301-306

  Sima, Anders A F ^a,d   Dunlap, Joyce A ^e   Davidson, Eric P ^e   Wiese, Thomas J ^e   Lightle, Rhonda L F ^b   Greene, Douglas A ^b   Yorek, Mark A ^c  

^a WAYNE STATE UNIVERSITY   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); FUCOSE; INOSITOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATROPHY; CONTROLLED STUDY; DEMYELINATION; DIABETIC NEUROPATHY; DIET SUPPLEMENTATION; ENZYME ACTIVITY; MALE; NERVE CONDUCTION; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SURAL NERVE;

EID: 0030904632     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diab.46.2.301     Document Type: Article

References (48)

1. Winegrad AI: Does a common mechanism induce the diverse complications of diabetes? Diabetes 36:396-406, 1987
2. Yorek MA, Dunlap JA, Ginsberg BH: Effect of sorbinil on myo-inositol metabolism in cultured neuroblastoma cells exposed to increased glucose levels. J Neurochem 51:331-338, 1988
3. Yorek MA, Dunlap JA: The effect of elevated glucose levels on myo-inositol metabolism in cultured bovine aortic endothelial cells. Metabolism 38:16-22, 1989
4. Greene DA, Lattimer SA, Sima AAF: Sorbitol, myo-inositol and sodium-potassium ATPase in the pathogenesis of diabetic complications. N Engl J Med 316:599-606, 1987
5. + ATPase activity. J Clin Invest 77:503-513, 1986
6. Greene DA, Sima AAF, Lattimer SA: Pathogenesis of diabetic neuropathy: role of altered phosphoinositide metabolism. In CRC Critical Reviews in Neurobiology. Vol. 5. Nelson J, Ed. Boca Raton, FL, CRC, 1989, p. 143-219
7. +-ATP-ase regulation involved in pathogenesis of diabetic neuropathy? Diabetes 37:688-693, 1988
8. Greene DA, Lattimer SA: Sodium and energy dependent uptake of myo-inositol by rabbit peripheral nerve. J Clin Invest 70:1009-1018, 1982
9. Gillon KRW, Hawthorn JN: Transport of myo-inositol into endoneurial preparations of sciatic nerve from normal and streptozotocin-diabetic rats. Biochem J 210:775-781, 1983
10. Honeda M, Arimura T, Umemura K, Kikkawa R: Sorbitol accumulation and myo-inositol depletion in cultured rat glomerular mesangial cells are induced by glucose (Abstract). Diabetes 37 (Suppl. 1):121A, 1988
11. Olgemoller B, Schwaabe S, Schleicher ED, Gerbitz KD: Competitive inhibition by glucose of myo-inositol incorporation into cultured porcine aortic endothelial cells. Biochem Biophys Acta 1052:47-52, 1990
12. Yorek MA, Stefani MR, Dunlap JA, Ro KS, Davidson EP: Transhydroxyl group configuration on carbons 2 and 3 of glucose: responsible for acute inhibition of myo-inositol transport? Diabetes 40:1016-1023, 1991
13. Burg MB, Kador PF: Sorbitol, osmoregulation and the complications of diabetes. J Clin Invest 81:635-640, 1988
14. Stevens MJ, Lattimer SA, Kamyo M, Van Huysen C, Sima AAF, Greene DA: Osmotically induced nerve taurine depletion in experimental diabetes: an hypothetical mediator of painful neuropathy. Diabetologia 36:608-614, 1993
15. Stevens M, Lattimer S, Feldman E, Sima AAF, Greene DA: Correction of nerve conduction slowing, nerve myo-inositol but not sorbitol by acetyl-L-carnitine in the streptozotocin-diabetic rat (Abstract). Diabetes 44 (Suppl. 1): 12A, 1995
16. Greene DA, Chakrabarti S, Lattimer SA, Sima AAF: Role of sorbitol accumulation and myoinositol depletion in paranodal swelling of large myelinated nerve fibers in the insulin-deficient spontaneously diabetic biobreeding rat. J Clin Invest 79:1479-1485, 1987
17. Sima AAF, Prashar A, Zhang W-X, Chakrabarti S, Greene DA: Preventive effect of long-term aldose reductase inhibition (Ponalrestat) on nerve conduction and sural nerve structure in the spontaneously diabetic BB-rat. J Clin Invest 85:1410-1420, 1990
18. Gillon KRW, Hawthorn JN, Tomlinson DR: Myo-inositol and sorbitol metabolism in relation to peripheral nerve function in experimental diabetes in the rat: the effect of aldose reductase inhibition. Diabetologia 25:365-371, 1983
19. +-ATPase activity in isolated membrane fraction from sciatic nerves of streptozotocin-induced rats by dietary myo-inositol supplementation in vivo or protein kinase C agonists in vivo. Diabetes 40:558-567, 1991
20. + pump activity in cultured neuroblastoma cells. Diabetes 38:996-1004, 1989
21. Greene DA, Sima AAF, Stevens M, Feldman E, Killen P, Henry D, Thomas T, Dannenberg J, Lattimer SA: Aldose reductase inhibitors: an approach to the treatment of the nerve damage of diabetic neuropathy. Diabetes Metab Rev 9:189-217, 1993
22. Cameron NE, Cotter MA, Dines KC, Maxfield EK, Carey F, Mirless D: Aldose reductase inhibition, nerve perfusion, oxygenation and function in streptozotocin-diabetic rats: dose response considerations and independence from myo-inositol mechanism. Diabetologia 37:651-663, 1994
23. Radhakrishnamurthy B, Berenson GS, Pargaonkar PS, Voors AW, Srinivasan SR, Plavidal F, Dolan P, Dalferes ER Jr: Serum free and protein bound sugars and cardiovascular complications in diabetes mellitus. Lab Invest 34:159-165, 1976
24. +-ATPase in rats maintained on a diet containing L-fucose: reversal by myo-inositol supplementation. Diabetes 42:1401-1406, 1993
25. Djurdjic V, Mandic L: A spectrophotometric method for simultaneous determination of protein-bound hexoses and fucose with a mixture of L-cysteine and phenol. Anal Biochem 188:222-227, 1990
26. Cohenford MA, Abraham A, Abraham J, Dain JA: Colorimetric assay of free and bound L-fucose. Anal Biochem 177:172-177, 1989
27. Yorek MA, Dunlop JA, Stefani MR, Davidson EP: L-fucose is a potent inhibitor of myo-inositol transport and metabolism in cultured neuroblastoma cells. J Neurochem 58:1626-1636, 1992
28. Sima AAF, Ristic H, Merry A, Kamijo M, Lattimer SA, Stevens MJ, Greene DA: The primary preventional and secondary interventative effects of acetyl-L-carnitine on diabetic neuropathy in the BB/W-rat. J Clin Invest 97:1900-1907, 1996
29. Yagihashi S, Kamijo M, Ido Y, Mirrlees DJ: Effects of long-term aldose reductase inhibition on development of experimental diabetic neuropathy: ultrastructural and morphometric studies of sural nerve in streptozocin-induced diabetic rats. Diabetes 39:690-696, 1990
30. Yagihashi S, Sugimoto K, Wada R: Different neuropathic patterns between type I and type II animal models. In Pathogenesis and Treatment of NIDDM and Its Related Problems. Sakomota N, Alberti KGMM, Hotta N, Eds. Amsterdam, Elsevier, 1994, p. 401-405
31. Sima AAF, Lattimer SA, Yagihashi S, Greene DA: "Axo-glial dysjunction": a novel structural lesion that accounts for poorly reversible slowing of nerve conduction in the spontaneously diabetic BB-rat. J Clin Invest 77:474-484, 1986
32. Brismar T, Sima AAF, Greene DA: Reversible and irreversible nodal dysfunction in diabetic neuropathy. Ann Neurol 21:504-507, 1987
33. Sima AAF, Bouchier M, Christensen H: Axonal atrophy in sensory nerves of the diabetic BB-Wistar rat, a possible early correlate of human diabetic neuropathy. Ann Neurol 13:264-272, 1983
34. Dyck PJ, Karnes JL, O'Brien P, Okazaki H, Lais A, Engelstad J: The spatial distribution of fiber loss in diabetic neuropathy suggests ischemia. Ann Neurol 19:440-449, 1986
35. Sima AAF, Nathaniel V, Prashar A, Bril V, Greene DA: Endoneurial microvessels in human diabetic neuropathy: endothelial cell dysjunction and lack of treatment effect by aldose reductase inhibitor. Diabetes 40:1090-1099, 1991
36. Sima AAF, Nathaniel V, Bril V, McEwen TAJ, Greene DA: Histopathological heterogeneity of neuropathy in insulin-dependent and non-insulin-dependent diabetes, and demonstration of axo-glial dysjunction in human diabetic neuropathy. J Clin Invest 81:349-364, 1988
37. Cameron NE, Cotter MA: The relationship of vascular changes to metabolic factors in diabetes mellitus and their role in the development of peripheral nerve complications. Diabetes Metab Rev 10:189-224, 1994
38. Tuck RR, Schmelzer JD, Low PA: Endoneurial blood flow and oxygen tension in the sciatic nerves of rats with experimental diabetic neuropathy. Brain 107:935-950, 1981
39. Cameron NE, Cotter MA, Low PA: Nerve blood flow in early experimental diabetes in rats: relation to conduction deficits. Am J Physiol 261:E1-E8, 1991
40. +)-ATPase in the slowing of nerve conduction in the streptozotocin diabetic rat. J Clin Invest 94:853-859, 1994
41. Cameron NE, Cotter MA, Robertson S: Essential fatty acid diet supplementation: effects on peripheral nerve and skeletal muscle function and capillarization in streptozotocin-induced diabetic rats. Diabetes 40:532-539, 1991
42. Cameron NE, Cotter MA, Dines KC, Maxfield EK: Pharmacological manipulation of vascular endothelium function in nondiabetic and streptozotocin-diabetic rats: effects on nerve conduction, hypoxic resistance and endoneurial capillarization. Diabetologia 36:516-522, 1993
43. Judzewitsch RG, Jaspan JB, Polonsky KS, Weinberg CR, Halter JB, Halar E, Pfeifer MA, Vucadinovic L, Bernstein L, Schneider M, Liang KY, Gabbay KH, Rubenstein AG, Porte D: Aldose reductase inhibition improves nerve conduction velocity in diabetic patients. N Engl J Med 308:119-125, 1983
44. Sima AAF, Bril V, Nathaniel V, McEwen TA, Brown M, Lattimer SA, Greene DA: Regeneration and repair of myelinated fibers in sural nerve biopsies from patients with diabetic neuropathy treated with an aldose reductase inhibitor. N Engl J Med 319:548-555, 1988
45. Yagihashi S, Kamijo M, Baba M, Yagihashi N, Nagai K: Effect of aminoguanidine on functional and structural abnormalities in peripheral nerve of STZ-induced diabetic rats. Diabetes 41:47-52, 1992
46. Cameron NE, Cotter MA, Archibald B, Dines KC, Maxfleld EK: Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats. Diabetologia 37:449-459, 1994
47. Greene DA, DeJesus PV, Winegrad AI: Effects of insulin and dietary myo-inositol on impaired motor nerve conduction velocity in acute streptozotocin diabetes. J Clin Invest 55:1326-1336, 1975
48. Tomlinson DR, Mayer JH: Reversal of deficits in axonal transport and nerve conduction velocity by treatment of streptozotocin diabetic rats with myo-inositol. Exp Neurol 89:420-427, 1985