Synthesis of Deuterated Plant Lignans for Gas Chromatography—Mass Spectrometry Analysis

Journal of Medicinal Food

Volumn 2, Issue , 1999, Pages 103-105

  Rasku, Sirpa ^a   Mazur, Witold ^a   Adlercreutz, Herman ^a   Wähälä, Kristiina ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

DEUTERIUM; LIGNAN; MATAIRESINOL; SECOISOLARICIRESINOL;

CHEMICAL REACTION; CHEMICAL STRUCTURE; CONFERENCE PAPER; GAS CHROMATOGRAPHY; ISOTOPE LABELING; MASS SPECTROMETRY; PRIORITY JOURNAL; REACTION ANALYSIS; STANDARD; SYNTHESIS;

EID: 0033502863     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.1999.2.103     Document Type: Article

References (12)

1. Adlercreutz, H., Fotsis, T., Bannwart, C., Wähälä, K., Brunow, G., and Hase, T. (1991). Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein. Clin Chim Acta 199, 263-278.
2. Adlercreutz, H., Fotsis, T., Watanabe, S., Lampe, J., Wähälä, K., Mäkelä, T., and Hase, T. (1994). Determination of lignans and isoflavonoids in plasma by isotope dilution gas cromatography-mass spectrometry. Cancer Detect Prev 18, 259-271.
3. Adlercreutz, H.T., Goldin, B.R., Gorbach, S.L., Höckerstedt, K.A.V., Watanabe, S., Hämäläinen, E.K., Markkanen, M.H., Mäkelä, T.H., Wähälä, K.T., Hase, T.A., and Fotsis, T. (1995a). Soybean phytoestrogen intake and cancer risk. J Nutr 125, 757S-770S.
4. Adlercreutz, H., van der Wildt, J., Kinzel, J., Attalla, H., Wähälä, K., Mäkelä, T., Hase, T., and Fotsis, T. (1995b). Lignan and isoflavonoid conjugates in human urine. J Steroid Biochem Mol Biol 52, 97-103.
5. Adlercreutz, H., Fotsis, T., Kurzer, M.S., Wähälä, K., Mäkelä, T., and Hase, T. (1995c). Isotope dilution gas chromatographic-mass spectrometric method for the determination of unconjugated lignans and isoflavonoids in human feces, with preliminary results in omnivorous and vegetarian women. Anal Biochem 225, 101-108.
6. Fotsis, T. and Adlercreutz, H. (1987). The multicomponent analysis of estrogens in urine by ion exchange chromatography and GC-MS-I: Quantitation of estrogens after initial hydrolysis of conjugates. J Steroid Biochem 28, 203-213.
7. Mazur, W., Fotsis, T., Wähälä, K., Ojala, S., Salakka, A., and Adlercreutz, H. (1996). Isotope dilution gas chromatographic-mass spectrometric method for the determination of isoflavonoids, coumestrol, and lignans in food samples. Anal Biochem 233, 169-180.
8. Mazur, W.M., Duke, J.A., Wähälä, K., Rasku, S., and Adlercreutz, H. (1998a). Isoflavonoids and lignans in legumes: Nutritional and health aspects in humans. Nutr Biochem 9, 193-200.
9. Mazur, W., Wähälä, K., Wang, G., and Adlercreutz, H. (1998b). Dietary phytoestrogens: From chemistry to chemoprevention. Kemia-Kemi 25, 48-55.
10. Mazur, W.M., Wähälä, K., Rasku, S., Salakka, A., Hase, T., and Adlercreutz, H. (1998c). Lignan and isoflavonoid concentrations in tea and coffee. Br J Nutr 79, 37-45.
11. Rasku, S., Wähälä, K., Koskimies, J., and Hase, T. (1999). Synthesis of isoflavonoid deuterium labeled polyphenolic phytoestrogens. Tetrahedron 55, 3445-3454.
12. 4-genistein, a stable deutero labeled isoflavone, by perdeuteration-selective dedeuteration approach. Tetrahedron 38, 7287-7290.