The molecular energetics of the failing heart from animal models - Small animal models

Heart Failure Reviews

Volumn 4, Issue 3, 1999, Pages 245-253

  Tian, Rong ^a,b   Ingwall, Joanne S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b NONE   (United States)

Author keywords

ATP; Calcium; Contractile performance; Creatine; Creatine kinase; Glycolysis; Phosphocreatine

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CREATINE; CREATINE KINASE; CREATINE PHOSPHATE; GLUCOSE;

CALCIUM HOMEOSTASIS; ENERGY METABOLISM; EXPERIMENTAL MODEL; GLUCOSE UTILIZATION; GLYCOLYSIS; HEART FAILURE; HEART HYPERTROPHY; HEART MUSCLE CONTRACTILITY; HEART MUSCLE METABOLISM; MITOCHONDRIAL ENERGY TRANSFER; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REVIEW; THERMODYNAMICS; TRANSGENIC ANIMAL;

EID: 0033496136     PISSN: 13824147     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1009862007475     Document Type: Review

References (36)

1. 31P NMR magnetization transfer study. J Biol Chem 1985;260:3512-3517.
2. Starling RC, Hammer DF, Altschuld RA. Human myocardial ATP content and in vivo contractile function. Mole Cell Biochem 1998;180:171-177.
3. 31P NMR Spectroscopy of the Mouse Heart. In: Hoit BD, Walsh RA, eds. Cardiovascular Physiology in the Genetically Engineered Mouse. Norwell, Mass: Kluwer Academic Publishers, 1998:183-191.
4. Aresta F, Chacko SM, Chacko VP, Weiss RG. In vivo non-invasive assessment of murine cardiac metabolism. JACC 1999;33:479A.
5. Shen W, Vatner DE, Shannon RP, Wagner TE, Homey CJ, Vatner SF, Ingwall JS. Impaired energetics contribute to cardiac dysfunction in transgenic mice overexpression of cardiac Csα. Circulation 1998;98(Suppl):I553.
6. Ingwall JS, Kramer MF, Fifer MA, Lorell BH, Shemin R, Grossman W, Allen PD. The creatine kinase system in normal and diseased human myocardium. N Engl J Med 1985;313:1050-1054.
7. Ingwall JS. Is cardiac failure a consequence of decreased energy reserve? Circulation 1993;87(Suppl VII):58-62.
8. Tian R, Nascimben L, Kaddurah-Daouk R, Ingwall JS. Depletion of energy reserve via the creatine kinase reaction during the evolution of heart failure in cardiomyopathic hamsters. J Mol Cell Cardiol 1996;28:755-765.
9. 31P NMR surface coil studies in brain, heart and skeletal muscle of the living rat. Biochemistry 1987;26:6083-6090.
10. McAuliffe JJ, Perry SB, Brooks EE, Ingwall JS. Kinetics of the creatine kinase reaction in neonatal rabbit heart: An empirical analysis of the rate equation. Biochemistry 1991;30:2585-2593.
11. Ingwall JS, Atkinson DA, Clarke K, Fetters JA. Energetic correlates of cardiac failure: Changes in the creatine kinase system in the failing myocardium. Eur Heart J 1990;11(Suppl B):108-115.
12. Bishop SP, Altschuld RA. Increased glycolytic metabolism in cardiac hypertrophy and congestive failure. Am J Physiol 1970;218(1):153-159.
13. Raizada V, Pathak D, Avery G, Woodfin B. Accelerated glycolysis in early hypertensive left ventricular hypertrophy. Cardiology 1993;83:160-164.
14. Taegtmeyer H, Overturf ML. Effects of moderate hypertension on cardiac function and metabolism in the rabbit. Hypertension 1988;11:416-426.
15. Nascimben L, Tian R, Lorell BH, Reis I, Weinberg EO, Ingwall JS. Rates of insulin-independent glucose entry and glycolysis are increased in hypertrophied hearts. Circulation 1995;92(8 Suppl 1):I-770.
16. Lopaschuk GD, Belke DD, Gamble J, Itoi T, Schonekess BO. Regulation of fatty acid oxidation in the mammalian heart in health and disease. Biochim Biophys Acta 1994;1213: 263-276.
17. Allard MF, Schonekess BO, Henning SL, English DR, Lopaschuk GD. Contribution of oxidative metabolism and glycolysis to ATP production in hypertrophied hearts. Am J Physiol/Heart Circ Physiol 1994;267(36):H742-H750.
18. Zhang J, Duncker DJ, Ya X, Zhang Y, Pavek T, Wei H, Merkle H, Ugurbil K, From AHL, Bache RJ. Effects of left ventricular hypertrophy secondary to chronic pressure overload on transmural myocardial 2-deoxyglucose uptake. A 31P NMR Spectroscopic study. Circulation 1995;92:1274-1283.
19. Kagaya Y, Kanno Y, Takeyama D, Ishide N, Maruyama Y, Takahashi T, Ido T, Takishima T. Effects of long-term pressure overload on regional myocardial glucose and free fatty acid uptake in rats. A quantitative autoradiographic study. Circulation 1990;81:1353-1361.
20. Nuutila P, Maki M, Laine H, Knuuti MJ, Ruotsalainen U, Luotolahti M, Haaparanta M, Solin O, Jula A, Koivisto VA, Voipio-Pulkki L-M, Yki-Jarvinene H. Insulin action on heart and skeletal muscle glucose uptake in essential hypertension. J Clin Invest 1995;96:1003-1009.
21. Tian R, Christe ME, Spindler M, Hopkins JCA, Halow JM, Camacho SA, Ingwall JS. The role of MgADP in the development of diastolic dysfunction in the intact beating rat hearts. J Clin Invest 1997;99:745-751.
22. Recchia FA, McConnell PI, Bernstein RD, Vogel TR, Xu X, Hintze TH. Reduced nitric oxide production and altered myocardial metabolism during the decompensation of pacing-induced heart failure in the conscious dog. Circ Res 1998;83:969-979.
23. Tian R, Nascimben L, Ingwall JS, Lorell BH. Failure to maintain a low ADP concentration impairs diastolic function in hypertrophied rat hearts. Circulation 1997;96:1313-1319.
24. Collins-Nakai RL, Noseworthy D, Lopaschuk GD. Epinephrine increases ATP production in hearts by preferentially increasing glucose metabolism. Am J Physiol/Heart Circ Physiol 1994;267(36):H1862-H1871.
25. Christe ME, Rodgers RL. Altered glucose and fatty acid oxidation in hearts of the spontaneously hypertensive rat. J Mol Cell Cardiol 1994;26:1371-1375.
26. Paternostro G, Clarke K, Heath J, Seymour A-M L, Radda GK. Decreased GLUT-4 mRNA content and insulin-sensitive deoxyglucose uptake show insulin resistance in the hypertensive rat heart. Cardiovasc Res 1995;30:205-211.
27. Hamman BL, Bittl JA, Jacobus WE, Allen PD, Spencer RS, Tian R, Ingwall JS. Inhibition of the creatine kinase reaction decreases the contractile reserve of the isolated rat heart. Am J Physiol 1995;269:H1030-1036.
28. Tian R, Ingwall JS. The energetic basis for reduced contractile reserve in isolated rat hearts. Am J Physiol 1996;270:H1207-H1216.
29. Gross WL, Bak MI, Ingwall JS, Arstall MA, Smith TW, Balligant J-L, Kelly RA. Nitric oxide inhibits creatine kinase and regulates rat heart contractile reserve. Proc Natl Acad Sci USA 1996;931:5604-5609.
30. 2+ handling contributes to decreased contractile reserve in rat hearts. Am J Physiol 1998;275:H2064-H2071.
31. 2+ content in cardiac myocytes. Am J Physiol 1995;268:C1313-C1329.
32. Morgan JP. Abnormal intracellular modulation of calcium as a major cause of cardiac dysfunction. N Engl J Med 1991; 325:625-632.
33. Neubauer S, Horn M, Naumann A, Tian R, Hu K, Laser M, Friedrich J, Gaudron P, Schnackerz K, Ingwall JS, Ertl G. Impairment of energy metabolism in intact residual myocardium of rat hearts with chronic myocardial infarction. J Clin Invest 1995;95:1092-1100.
34. 31P nuclear magnetic resonance spectroscopic imaging of regions of remodeled myocardium in the infarcted rat heart. Circulation 1995;92:3527-3538.
35. Nascimben L, Friedrich J, Liao R, Pauletto P, Pessina AC, Ingwall JS. Enalapril treatment increases cardiac performance and energy reserve via the creatine kinase reaction in myocardium of Syrian myopathic hamsters with advanced heart failure. Circulation 1995;91:1824-1833.
36. Liao R, Nascimben L. Friedrich J. Gwathmey JK, Ingwall JS. Decreased energy reserve in an animal model of dilated cardiomyopathy: Relationship to contractile performance. Circ Res 1996;78:893-902.