Oxidation of an oil rich in docosahexaenoic acid compared to linoleic acid in lactating women

Annals of Nutrition and Metabolism

Volumn 43, Issue 6, 1999, Pages 339-345

  Fidler, N ^a   Sauerwald, T ^a   Demmelmair, H ^a   Pohl, A ^a   Koletzko, Berthold ^a,b  

^a UNIVERSITY OF MUNICH   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

13C labeled fatty acids; Docosahexaenoic acid; Isotopic ratio mass spectrometry; Lactation; Linoleic acid; Oxidation

Indexed keywords

CARBON 13; CARBON DIOXIDE; DOCOSAHEXAENOIC ACID; LINOLEIC ACID;

ADULT; ARTICLE; BREAST FEEDING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DRUG ABSORPTION; DRUG OXIDATION; FEMALE; HUMAN; HUMAN EXPERIMENT; ISOTOPE LABELING; LACTATION; LIPID COMPOSITION; MASS SPECTROMETRY; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0033494982     PISSN: 02506807     EISSN: None     Source Type: Journal    
DOI: 10.1159/000012802     Document Type: Article

References (15)

1. 13C-labeled linoleic acid in lactating women. J Lipid Res 1998;39:1389-1396.
2. Hachey DL, Thomas MR, Emken EA, Garza C, Brown-Booth L, Adolf RO, Klein PD: Human lactation: Maternal transfer of dietary triglycerides labeled with stable isotopes. J Lipid Res 1987;28:1185-1192.
3. Martin JC, Bougnoux P, Fignon A, Theret V, Antonie JM, Lamisse F, Couet C: Dependence of human milk essential fatty acids on adipose stores during lactation. Am J Clin Nutr 1993;58:653-659.
4. Koletzko B, Sauerwald T, Demmelmair H: Safety of stable isotope use. Eur J Pediatr 1997;156(suppl 1):12-17.
5. Koletzko B, Demmelmair H, Hartl W, Kindermann A, Koletzko S, Sauerwald T, Szitanyi P: The use of stable isotope techniques for nutritional and metabolic research in paediatrics. Early Hum Dev 1998; 53(supl):77-97.
6. Rating D, Langhaus CD: Breath tests: Concepts, applications and limitations. Eur J Pediatr 1997; 156(suppl 1):18-23.
7. Kyle DJ, Sicotte VJ, Singer JJ, Reeb SE: Bioproduction of docosahexaenoic acid (DHA) by microalgae; in Kyle DJ, Ratledge C (eds): Industrial Applications of Single Cell Oils. Champaign, American Oil Chemists' Society, 1992, pp 287-300.
8. Boswell K, Koskelo EK, Carl L, Glaza S, Hensen DJ, Williams KD, Kyle DJ: Preclinical evaluation of single-cell oils that are highly enriched with arachidonic acid and docosahexaenoic acid. Food Chem Toxicol 1996;34:585-593.
9. Klein PD, Klein ER: Stable isotopes: Origins and safety. J Clin Pharmacol 1986;26:378-382.
10. Jones PJH, Leatherdale ST: Stable isotopes in clinical research: Safety reaffirmed. Clin Sci (Colch) 1991; 80:277-280.
11. Heiling VJ, Miles JM, Jensen MD: How valid are isotopic measurements of fatty acid oxidation? Am J Physiol 1991;261:E572-E577.
12. 2 breath tests: Methodology and fundamental considerations. J Lab Clin Med 1997; 90:412-421.
13. Demmelmair H, Sauerwald T, Koletzko B, Richter T: New insights into lipid and fatty acid metabolism via stable isotopes. Eur J Pediatr 1997;156(suppl 1):70-74.
14. Krumbiegel P: Stable Isotope Pharmaceuticals for Clinical Research and Diagnosis. Jena, Fischer, 1991. pp 70-72.
15. 13C: A comparison of oxidation after oral or parenteral administration in humans. J Nutr 1991;121: 31-36.