SUM-159PT cells: A novel estrogen independent human breast cancer model system

Breast Cancer Research and Treatment

Volumn 58, Issue 3, 1999, Pages 193-204

  Flanagan, Louise ^a,b   Van Weelden, Kathryn ^b   Ammerman, Cheryl ^c   Ethier, Stephen P ^c   Welsh, JoEllen ^b  

^a UNIVERSITY COLLEGE DUBLIN   (Ireland)

^b UNIVERSITY OF NOTRE DAME   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Breast cancer; Estrogen independent; MCF 7 cells; Metastases; SUM 159PT cells

Indexed keywords

CALCITRIOL; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR; MATRIGEL; PHORBOL ESTER; TRANSFORMING GROWTH FACTOR BETA; UVOMORULIN; VIMENTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL CULTURE; CANCER INHIBITION; CANCER TRANSPLANTATION; CELL STRAIN MCF 7; CELL TRANSFORMATION; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; HORMONE BINDING; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIGAND BINDING; METASTASIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOGRAFT;

ANIMALS; BREAST NEOPLASMS; DISEASE MODELS, ANIMAL; ESTRADIOL; FEMALE; HUMANS; MICE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; RECEPTORS, ESTROGEN; TRANSFORMING GROWTH FACTOR BETA; TRANSPLANTATION, HETEROLOGOUS; TUMOR CELLS, CULTURED;

EID: 0033492698     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006331716981     Document Type: Article

References (35)

1. 1. Association AC, Cancer Facts and Figures-1997, American Cancer Society, Inc.: Atlanta.
2. 2. Liotta LA: Cancer cell invasion and metastasis. Scientific American 226: 54-63, 1992
3. 3. Chambers AF, Matrisian LM: Changing views of the role of matrix metalloproteinases in metastasis. J Natl Cancer Inst 89(17): 1260-1270, 1997
4. 4. Fidler IJ: Critical factors in the biology of human cancer metastasis. Twenty-eighth G.H.A. Clowes memorial award lecture. Cancer Res 50(19): 6130-6138, 1990
5. 5. Seshadri R, Raymond WA, Leong AS, Horsfall DJ, McCaul K: Vimentin expression is not associated with poor prognosis in breast cancer. Int J Cancer 67(3): 353-356, 1996
6. 6. Thompson EW, Paik S, Brunner N, Sommers CL, Zugmaier G, Clarke R, Shima TB, Toni J, Donahue S, Lippman ME: Association of increased basement membrane invasiveness with absence of estrogen receptor and expression of vimentin in human breast cancer cell lines. J Cell Physiol 150(3): 534-544, 1992
7. 7. Cattoretti G, Andreola S, Clemente C, D'Amato L, Rilke F: Vimentin and p53 expression on epidermal growth factor receptor-positive, oestrogen receptor-negative breast carcinomas. Br J Cancer 57: 353-357, 1988
8. 8. Hendrix MJ, Seftor FA, Seftor RE, Trevor KT: Experimental co-expression of vimentin and keratin intermediate filaments in human breast cancer cells results in phenotypic interconversion and increased invasive behavior. Am J Pathol 150(2): 483-495, 1997
9. 9. Sommers CL, Byers SW, Thompson EW, Torri JA, Gelmann EP: Differentiation state and invasiveness of human breast cancer cell lines. Breast Cancer Res Treat 31(2-3): 325-335, 1994
10. 10. Siitonen SM, Kononen JT, Helin HJ, Rantala IS, Holli KA, Isola JJ: Reduced E-cadherin expression is associated with invasiveness and unfavorable prognosis in breast cancer. Am J Clin Pathol 105(4): 394-402, 1996
11. 11. Behrens J, Mareel MM, Van Roy FM, Birchmeier W: Dissecting tumor cell invasion: epithelial cells acquire invasive properties after the loss of uvomorulin mediated cell-cell adhesion. J Cell Biol 108(6): 2435-2447, 1989
12. 12. Sommers CL, Thompson EW, Torri JA, Kemler R, Gelmann EP, Byers SW: Cell adhesion molecule uvomorulin expression in human breast cancer cell lines: relationship to morphology and invasive capacities. Cell Growth Differ 2(8): 365-372, 1991
13. fak in eleven newly isolated human breast cancer cell lines. Breast Cancer Res Treat 54: 173-182, 1999
14. 14. Forozan F, Veldman R, Ammerman CA, Parsa NZ, Kallioniemi A, Kallioniemi O, Ethier SP: Phenotypic and genetic characterization of 11 new breast cancer cell lines. Brit J Cancer (In press)
15. 15. Ethier SP, Mahacek ML, Gullick WJ, Frank TS, Weber BL: Differential isolation of normal luminal mammary epithelial cells and breast cancer cells from primary and metastatic sites using selective media Cancer Res 53: 627-635, 1993
16. 16. Sommers CL, Walker-Jones D, Heckford SE, Worland P, Valverius E, Clark R, McCormick F, Stampfer M, Abularach S, Gelmann EP: Vimentin rather than keratin expression in some hormone-independent breast cancer cell lines and in oncogene-transformed mammary epithelial cells. Cancer Res 49: 4258-4263, 1989
17. 17. Athanassiadou P, Athanassiades P, Kyrkou K, Giahnaki E, Giannioti E, Nanas S: Expression of vimentin and epidermal growth factor receptor in effusions from patients with breast cancer; correlation with oestrogen and progesterone receptor status. Cytopathology 4(2): 91-98, 1993
18. 18. Stover DM, Carey I, Garzon RJ, Zehner ZE: A negative regulatory factor is missing in a human metastatic breast cancer cell line. Cancer Res 54(12): 3092-3095, 1994
19. 19. Kramer RH, Bensch KG, Wong J: Invasion of reconstituted basement membrane matrix by metastatic human tumor cells. Cancer Res 46: 1980-1986, 1986
20. 20. Price JE, Polyzos A, Zhang RD, Daniels LM: Tumorigenicity and metastasis of human breast carcinoma cell lines in nude mice. Cancer Res 50(3): 717-721, 1990
21. 21. Bao L, Matsumura Y, Baban D, Sun Y, Tarin D: Effects of inoculation site and Matrigel on growth and metastasis of human breast cancer cells. Br J Cancer 70(2): 228-232, 1994
22. 22. Miller FR: Comparison of metastasis of mammary tumors growing in the mammary fatpad versus the subcutis. Invasion Metastasis 1(4): 220-226, 1981
23. 23. Price JE: Metastasis from human breast cancer cell lines. Breast Cancer Res Treat 39(1): 93-102, 1996
24. 24. Buras RR, Schumaker LM, Davoodi F, Brenner RV, Shabahang M, Nauta RJ, Evans SR: Vitamin D receptors in breast cancer cells. Breast Cancer Res Treat 31(2-3): 191-202, 1994
25. 3 induces morphological and biochemical markers of apoptosis in MCF-7 breast cancer cells. J Steroid Biochem Mol Biol 58(4): 367-376, 1996
26. 3 and EB1089 on cell cycle kinetics and apoptosis in MCF-7 breast cancer cells. Breast Cancer Res Treat 42(1): 31-41, 1997
27. 27. Clarke R, Skaar T, Baumann K, Leonessa F, James M, Lippman J, Thompson EW, Freter C, Brunner N: Hormonal carcinogenesis in breast cancer: cellular and molecular studies of malignant progression. Breast Cancer Res Treat 31(2-3): 237-248, 1994
28. 28. Brunner N, Frandsen TL, Holst-Hansen C, Bei M, Thompson EW, Wakeling AE, Lippman ME, Clarke R: MCF7/LCC2: a 4-hydroxytamoxifen resistant human breast cancer variant that retains sensitivity to the steroidal antiestrogen ICI 182,780. Cancer Res 53(14): 3229-3232, 1993
29. 29. Byers S, Pishvaian M, Crockett C, Peer C, Tozeren A, Sporn M, Anzano M, Lechleider R: Retinoids increase cell-cell adhesion strength, beta-catenin protein stability, and localization to the cell membrane in a breast cancer cell line: a role for serine kinase activity. Endocrinology 137(8): 3265-3273, 1996
30. 30. Bracke ME, Charlier C, Bruyneel EA, Labit C, Mareel MM, Castronovo V: Tamoxifen restores the E-cadherin function in human breast cancer MCF-7/6 cells and suppresses their invasive phenotype. Cancer Res 54(17): 4607-4609, 1994
31. 31. Vleminckx K, Vakaet L, Mareel M, Fiers W, van Roy F: Genetic manipulation of E-cadherin expression by epithelial tumor cell reveals an invasion suppressor role. Cell 66: 107-119, 1991
32. 32. Arteaga CL, Tandon AK, Von Hoff DD, Osborne CK: Transforming growth factor beta: potential autocrine growth inhibitor of estrogen receptor-negative human breast cancer cells. Cancer Res 48(14): 3898-3904, 1988
33. 33. Welsh J: Induction of apoptosis in breast cancer cells in response to vitamin D and antiestrogens. Biochem Cell Biol 72: 537-545, 1994
34. 3 and its analogues on induction of apoptosis in breast cancer cells. J Steroid Biochem Mol Biol 58: 395-401, 1996
35. 3 receptor in breast cancer and relationship to prognosis. Cancer Res 51: 239-244, 1991