Assessment of ethanol intake: Current tests and new assays on the horizon

American Journal of Clinical Pathology

Volumn 112, Issue 4, 1999, Pages 443-450

  Laposata, Michael ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Alcohol; Carbohydrate deficient transferrin; Drug abuse; Fatty acid ethyl ester; Toxicology

Indexed keywords

5 HYDROXYTRYPTOPHOL; ACETALDEHYDE; FATTY ACID ESTER; PHOSPHATIDYLETHANOLAMINE; TRANSFERRIN;

ALCOHOL CONSUMPTION; BREATH ANALYSIS; ENZYME ASSAY; GAS CHROMATOGRAPHY; HUMAN; PRIORITY JOURNAL; REVIEW; SALIVA ANALYSIS; SCREENING TEST; URINALYSIS; VITREOUS BODY;

EID: 0033492344     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcp/112.4.443     Document Type: Review

References (34)

1. Laposata M. Fatty acid ethyl esters: short-term and long-term serum markers of ethanol intake. Clin Chem. 1997;43:1527-1534.
2. Bean P. Carbohydrate-deficient transferrin in the diagnosis of alcohol abuse: diagnostic performance and clinical significance. LabMedica Int. 1997;14:16-19.
3. Helander A, Beck O, Jones AW. Laboratory testing for recent alcohol consumption: comparison of ethanol, methanol, and 5-hydroxytryptophol. Clin Chem. 1996;42:618-624.
4. Hernandez-Munoz R, Ma X-L, Baraona E, et al. Method of acetaldehyde measurement with minimal artifactual formation in red blood cells and plasma of actively drinking subjects with alcoholism. J Lab Clin Med. 1992;120:35-41.
5. Sillanaukee, P, Seppa K, Koivula T, et al. Acetaldehyde-modified hemoglobin as a marker of alcohol consumption: comparison of two new methods. J Clin Lab Med. 1992;120:42-47.
6. Worrall, S, de Jersey J, Wilce PA, et al. Relationship between alcohol intake and immunoglobulin A immunoreactivity with acetaldehyde-modified bovine serum albumin. Alcohol Clin Exp Res. 1996;20:836-840.
7. Lin RC, Shahidi S, Kelly TJ, et al. Measurement of hemoglobin-acetaldehyde adduct in alcoholic patients. Alcohol Clin Exp Res. 1993;17:669-674.
8. Hansson P, Caron M, Johnson G, et al. Blood phosphatidylethanol as a marker of alcohol abuse: levels in alcoholic males during withdrawal. Alcohol Clin Exp Res. 1997;21:108-110.
9. Wu AHB. Pharmacokinetic aspects of ethanol for medicolegal purposes. Am Assoc Clin Chem Briefing. 1991;12:5-13.
10. Clothier J, Kelly JT, Reed KE, et al. Varying rates of alcohol metabolism. Alcohol. 1985;2:443-445.
11. Levine, B. Postmortem forensic toxicology. Am Assoc Clin Chem Briefing. 1994;15:7-12.
12. Abbott Laboratories. REA Ethanol. Abbott Park, IL: Abbott Laboratories; 1995. List No. 3832-20.
13. Payne JP, Hill DW, Wood DGL. Distribution of ethanol between plasma and erythrocytes in whole blood. BMJ. 1968;3:819-823.
14. Wu AHB. Near-patient and point-of-care testing for alcohol and drugs of abuse. Am Assoc Clin Chem Briefing. 1995;16:227-236.
15. Forney RB, Hughes FW, Harger RN, et al. Alcohol distribution in the vascular system. Q J Stud Alcohol. 1964;25:205-217.
16. Chao TC, Lo DST. Relationship between postmortem blood and vitreous humor ethanol levels. Am J Forensic Med Pathol. 1993;14:303-308.
17. Bean P, Liegmann K, Løvli T, et al. Semiautomated procedures for evaluation of carbohydrate-deficient transferrin in the diagnosis of alcohol abuse. Clin Chem. 1997;43:983-989.
18. Vermes I, van den Bergh FAJTM. Clinical utility of carbohydrate deficient transferrin to detect alcohol abuse in a general population. Clin Chem. 1996;42:2048-2049.
19. Lesch OM, Walter H, Antal J, et al. Carbohydrate-deficient transferrin as a marker of alcohol intake: a study with healthy subjects. Alcohol Alcohol. 1996;31:265-271.
20. Huseby N-E, Bjordal E, Nilssen O, et al. Utility of biological markers during outpatient treatment of alcohol-dependent subjects: carbohydrate-deficient transferrin responds to moderate changes in alcohol consumption. Alcohol Clin Exp Res. 1997;21:1343-1346.
21. Reynaud M, Hourcade F, Planche F, et al. Usefulness of carbohydrate-deficient transferrin in alcoholic patients with normal γ-glutamyltranspeptidase. Alcohol Clin Exp Res. 1998;22:615-618.
22. Radosavljevic M, Temsch E, Hammer J, et al. Elevated levels of serum carbohydrate deficient transferrin are not specific for alcohol abuse in patients with liver disease. J Hepatol. 1995;23:706-711.
23. Huseby N-E, Nilssen O, Erfuth A, et al. Carbohydrate-deficient transform and alcohol dependency: variation in response to alcohol intake among different groups of patients. Alcohol Clin Exp Res. 1997;21:201-205.
24. Rubio M, Caballeria J, Deulofeu R, et al. Carbohydrate-deficient transferrin as a marker of alcohol consumption in male patients with liver disease. Alcohol Clin Exp Res. 1997;21:923-927.
25. Murawaki Y, Sugisaki H, Yuasa I, et al. Serum carbohydrate-deficient transferrin in patients with nonalcoholic liver disease and with hepatocellular carcinoma. Clin Chim Acta. 1997;259:97-108.
26. Stauber RE, Vollmann H, Pesserl I, et al. Carbohydrate-deficient transferrin in healthy women: relation to estrogens and iron status. Alcohol Clin Exp Res. 1996;20:1114-1117.
27. Arndt T, Hackler R, Müller T, et al. Increased serum concentration of carbohydrate-deficient transferrin in patients with combined pancreas and kidney transplantation. Clin Chem. 1997;42:344-351.
28. Laposata EA, Lange LG. Presence of nonoxidative ethanol metabolism in human organisms commonly damaged by ethanol abuse. Science. 1986;231:497-499.
29. Szczepiorkowski ZM, Dickerson GR, Laposata M. Fatty acid ethyl esters decrease human hepatoblastoma cell proliferation and protein synthesis. Gastroenterology. 1995;108:515-522.
30. Werner J, Laposata M, Fernandez-del Castillo C, et al. Pancreatic injury in rats induced by fatty acid ethyl ester, a non-oxidative metabolite of alcohol. Gastroenterology. 1997;113:286-294.
31. Doyle KM, Cluette-Brown JE, Dube DM, et al. Fatty acid ethyl esters in the blood as markers for ethanol intake. JAMA. 1996;276:1152-1156.
32. Voltaire A, Beck O, Borg S. Urinary 5-hydroxytryptophol: a possible marker of recent alcohol consumption. Alcohol Clin Exp Res. 1992;16:281-285.
33. Conigrave KM, Saunders JB, Whitfield JB. Diagnostic tests for alcohol consumption. Alcohol Alcohol. 1995;30:13-26.
34. Lundqvist C, Ailing C, Aradottir S, et al. Agonist-stimulated and basal phosphatidylethanol formation in neutrophils from alcoholics. Alcohol Clin Exp Res. 1994;18:580-586.