Aging and high concentrations of glucose potentiate injury to mitochondrial DNA

Free Radical Biology and Medicine

Volumn 27, Issue 11-12, 1999, Pages 1437-1443

  Fukagawa, Naomi K ^a   Li, Muyao ^a   Liang, Ping ^a   Russell, James C ^b   Sobel, Burton E ^a   Absher, P Marlene ^a  

^a UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF ALBERTA   (Canada)

Author keywords

Aging; Free radicals; Glucose; Mitochondrial DNA; Oxidative stress; Vascular smooth muscle cells

Indexed keywords

ADVANCED GLYCATION END PRODUCT; FREE RADICAL; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE;

AGING; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA DAMAGE; GENE DELETION; GENE MUTATION; GENOTYPE; HYPERGLYCEMIA; HYPERINSULINEMIA; MALE; NONHUMAN; OXIDATIVE STRESS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RAT; SKELETAL MUSCLE; SOMATIC MUTATION; VASCULAR SMOOTH MUSCLE;

AGING; ANIMALS; BASE PAIRING; BLOOD GLUCOSE; DNA DAMAGE; DNA, MITOCHONDRIAL; GENE DELETION; GLUCOSE; HYPERINSULINISM; HYPERLIPIDEMIAS; INSULIN RESISTANCE; MALE; MUSCLE, SKELETAL; MUSCLE, SMOOTH, VASCULAR; MUTATION; OXIDATIVE STRESS; RATS; RATS, MUTANT STRAINS; REACTIVE OXYGEN SPECIES;

EID: 0033461149     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(99)00189-6     Document Type: Article

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