Differential mechanisms for structural and functional alterations of trypsin by heparin, evidence for a specific, radical-generating mechanism at low heparin concentrations

Free Radical Biology and Medicine

Volumn 27, Issue 11-12, 1999, Pages 1378-1385

  Finotti, Paola ^a   Corvaja, Carlo ^a   Pagetta, Andrea ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Bovine; Free radical; Heparin; Protein structure; Radicals; Trypsin

Indexed keywords

HEPARIN; TRYPSIN;

ARTICLE; DRUG PROTEIN BINDING; ELECTROPHORESIS; ENZYME ACTIVITY; ENZYME MODIFICATION; ENZYME STRUCTURE; FLUORESCENCE SPECTROSCOPY; OXIDATION; PRIORITY JOURNAL;

ANIMALS; CATTLE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FREE RADICALS; HEPARIN; HEPARIN LYASE; PEPTIDE FRAGMENTS; SPECTROMETRY, FLUORESCENCE; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPSIN;

BOVINAE;

EID: 0033458080     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(99)00185-9     Document Type: Article

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