Spin-trapping agent α-phenyl N-tert-butylnitrone binds to trypsin and enhances heparin-induced inhibition of amidolytic activity and structural degradation of the enzyme

FEBS Letters

Volumn 453, Issue 1-2, 1999, Pages 159-163

  Finotti, Paola ^a   Corvaja, Carlo ^a   Pagetta, Andrea ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Phenyl N tert butylnitrone; Bovine; Enzyme inhibition; Heparin; Oxidation; Trypsin

Indexed keywords

HEPARIN; N TERT BUTYL ALPHA PHENYLNITRONE; TRYPSIN;

ARTICLE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME INHIBITION; OXIDATION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN STRUCTURE; SPIN TRAPPING;

AMIDOHYDROLASES; DRUG INTERACTIONS; HEPARIN; NITROGEN OXIDES; OXIDATION-REDUCTION; SPIN TRAPPING; TRYPSIN; TRYPSIN INHIBITORS;

EID: 0032768755     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(99)00716-4     Document Type: Article

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