Specific mutations in a viral RNA pseudoknot drastically change ribosomal frameshifting efficiency

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 25, 1999, Pages 14234-14239

  Kim, Yang Gyun ^a   Su, Li ^a   Maas, Stefan ^a   O'Neill, Analeah ^a   Rich, Alexander ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Hydrogen bond; Ribosome movement; RNA structure; RNA triplex

Indexed keywords

VIRUS RNA;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; EMBRYO; ENVIRONMENT; HUMAN; HUMAN CELL; HYDROGEN BOND; KIDNEY CELL; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; RABBIT; RETICULOCYTE LYSATE; RIBOSOMAL FRAMESHIFTING; RNA STRUCTURE; VIRUS REPLICATION;

NON-PROGRAMMATIC;

CELLS, CULTURED; HYDROGEN BONDING; MUTATION; NUCLEIC ACID CONFORMATION; RIBOSOMES; RNA, VIRAL; STRUCTURE-ACTIVITY RELATIONSHIP;

ANIMALIA; BEET WESTERN YELLOWS VIRUS; BETA VULGARIS SUBSP. VULGARIS; ORYCTOLAGUS CUNICULUS; RNA VIRUSES;

EID: 0033452721     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.25.14234     Document Type: Article

References (29)

1. Jacks, T., Madhani, H. D., Masiarz, F. R. & Varmus, H. E. (1988) Cell 55, 447-458.
2. Chamorro, M., Parkin, N. & Varmus, H. E. (1992) Proc. Natl. Acad. Sci. USA 89, 713-717.
3. ten Dam, E., Brierley, I., Inglis, S. & Pleij, C. (1994) Nucleic Acids Res. 22, 2304-2310.
4. Brierley, I., Rolley, N. J., Jenner, A. J. & Inglis, S. C. (1991) J. Mol. Biol. 220, 889-902.
5. Tzeng, T. H., Tu, C. L. & Bruenn, J. A. (1992) J. Virol. 66, 999-1006.
6. Miller, W. A., Dinesh-Kumar, S. P. & Paul, C. P. (1995) Crit. Rev. Plant Sci. 14, 179-211.
7. Gesteland, R. F. & Atkins, J. F. (1996) Annu. Rev. Biochem. 65, 741-768.
8. Pleij, C. W., Rietveld, K. & Bosch, L. (1985) Nucleic Acids Res. 13, 1717-1731.
9. Tu, C., Tzeng, T. H. & Bruenn, J. A. (1992) Proc. Natl. Acad. Sci. USA 89, 8636-8640.
10. Chen, L., Cai, L., Zhang, X. & Rich, A. (1994) Biochemistry 33, 13540-13546.
11. ten Dam, E. B., Verlaan, P. W. & Pleij, C. W. (1995) RNA 1, 146-154.
12. Shen, L. X. & Tinoco, I., Jr. (1995) J. Mol. Biol. 247, 963-978.
13. Du, Z., Giedroc, D. P. & Hoffman, D. W. (1996) Biochemistry 35, 4187-4198.
14. Kang, H. & Tinoco, I., Jr. (1997) Nucleic Acids Res. 25, 1943-1949.
15. Su, L., Chen, L., Egli, M., Berger, J. M. & Rich, A. (1999) Nat. Struct. Biol. 6, 285-292.
16. Garcia, A., van Duin, J. & Pleij, C. W. (1993) Nucleic Acids Res. 21, 401-406.
17. Felgner, P. L. & Ringold, G. M. (1989) Nature (London) 337, 387-388.
18. Reil, H., Kollmus, H., Weidle, U. H. & Hauser, H. (1993) J. Virol. 67, 5579-5584.
19. Pley, H. W., Flaherty, K. M. & McKay, D. B. (1994) Nature (London) 372, 111-113.
20. Napthine, S., Liphardt, J., Bloys, A., Routledge, S. & Brierley, I. (1999) J. Mol. Biol. 288, 305-320.
21. Saenger, W. (1984) Principles of Nucleic Acid Structure (Springer, New York), pp. 242-252.
22. Kielkopf, C. L., White, S., Szewczyk, J. W., Turner, J. M., Baird, E. E., Dervan, P. B. & Rees, D. C. (1998) Science 282, 111-115.
23. Liphardt, J., Napthine, S., Kontos, H. & Brierley, I. (1999) J. Mol. Biol. 288, 321-335.
24. Sung, D. & Kang, H. (1998) Nucleic Acids Res. 26, 1369-1372.
25. Chen, X., Chamorro, M., Lee, S. I., Shen, L. X., Hines, J. V., Tinoco, I., Jr. & Varmus, H. E. (1995) EMBO J. 14, 842-852.
26. Theimer, C. A., Wang, Y., Hoffman, D. W., Krisch, H. M. & Giedroc, D. P. (1998) J. Mol. Biol. 279, 545-564.
27. Parkin, N. T., Chamorro, M. & Varmus, H. E. (1992) J. Virol. 66, 5147-5151.
28. Wills, N. M., Gesteland, R. F. & Atkins, J. F. (1994) EMBO J. 13, 4137-4144.
29. Somogyi, P., Jenner, A. J., Brierley, I. & Inglis, S. C. (1993) Mol. Cell Biol. 13, 6931-6940.