Efficacy of treating hypertension in women

Journal of General Internal Medicine

Volumn 14, Issue 12, 1999, Pages 718-729

  Quan, Anna ^a,d   Kerlikowske, Karla ^b   Gueyffier, Francois ^c   Boissel, Jean Pierre ^c  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITÉ LYON 1   (France)

^d VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

Age; Hypertension; Race; Treatment; Women

Indexed keywords

AMILORIDE PLUS HYDROCHLOROTHIAZIDE; ANTIHYPERTENSIVE AGENT; ATENOLOL; BENDROFLUMETHIAZIDE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CHLOROTHIAZIDE; CHLORTALIDONE; CLONIDINE; DIURETIC AGENT; HYDROCHLOROTHIAZIDE PLUS TRIAMTERENE; METOPROLOL; NIFEDIPINE; NITRENDIPINE; PINDOLOL; PROPRANOLOL;

ARTICLE; CARDIOVASCULAR DISEASE; CEREBROVASCULAR DISEASE; CLINICAL TRIAL; DRUG EFFICACY; FATALITY; FEMALE; HUMAN; HYPERTENSION; MENOPAUSE; META ANALYSIS; MORBIDITY; OUTCOMES RESEARCH; RACE DIFFERENCE; RISK BENEFIT ANALYSIS;

ADULT; AGE DISTRIBUTION; AGED; ANTIHYPERTENSIVE AGENTS; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERTENSION; INCIDENCE; LOGISTIC MODELS; MIDDLE AGED; MULTIVARIATE ANALYSIS; RANDOMIZED CONTROLLED TRIALS; RISK FACTORS; SURVIVAL RATE; TREATMENT OUTCOME;

EID: 0033452090     PISSN: 08848734     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1525-1497.1999.12198.x     Document Type: Article

References (73)

1. 1. Wenger NK, Speroff L, Parkard B. Cardiovascular health and disease in women. N Engl J Med. 1993;329:247-56.
2. 2. Kaplan NM. The treatment of hypertension in women. Arch Intern Med. 1995;155:563-7.
3. 3. Kuhn FE, Rackley CE. Coronary artery disease in women: risk factors, evaluation, treatment, and prevention. Arch Intern Med. 1993;153:2626-36.
4. 4. Hayes SN, Taler SJ. Hypertension in women: current understanding of gender differences. Mayo Clin Proc. 1998;73:157-65.
5. 5. The sixth report of the Joint National Committee on prevention, detection, evaluation, and treatment of high blood pressure. Arch Intern Med. 1997;157:2413-46.
6. 6. Collins R, Peto R, MacMahon S, et al. Blood pressure, stroke, and coronary heart disease, part 2: short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet. 1990;335:827-38.
7. 7. Insua JT, Sacks HS, Lau TS, et al. Drug treatment of hypertension in the elderly: a meta-analysis. Ann Intern Med. 1994;121: 355-62.
8. 8. Mulrow CD, Cornell JA, Herrera CR, Kadri A, Farnett L, Aguilar C. Hypertension in the elderly: implications and generalizability of randomized trials. JAMA. 1994;272:1932-8.
9. 9. Psaty BM, Smith NL, Siscovick DS, et al. Health outcomes associated with antihypertensive therapies used as first line agents. JAMA. 1997;277:739-45.
10. 10. Gueyfficr F, Boutitie F, Boissel JP, et al. Effect of antihypertensive drug treatment on cardiovascular outcomes in women and men: a meta-analysis of individual patient data from randomized, controlled trials. Ann Intern Med. 1997;126:761-7.
11. 11. Anastos K, Charney P, Charon RA, et al, for the Women's Caucus, Working Group on Women's Health of the Society of General Internal Medicine. Hypertension in women: what is really known? Ann Intern Med. 1991;115:287-93.
12. 12. Schnall PL, Alderman MH, Kern R. An analysis of the HDFP trial: evidence of adverse effects of antihypertensive treatment on white women with moderate and severe hypertension. NY State J Med 1984;84:299-301.
13. 13. Medical Research Council Working Party. MRC trial of treatment of mild hypertension: principal results. BMJ. 1985;291:97-104.
14. 14. Hypertension Detection and Follow-up Program Cooperative Group. Five-year findings of the hypertension detection and follow-up program, I: reduction in mortality of persons with high blood pressure, including mild hypertension. JAMA. 1979;242:2562-71.
15. 15. Hypertension Detection and Follow-up Program Cooperative Group. Five-year findings of the hypertension detection and follow-up program, II: mortality by race-sex and age. JAMA. 1979;242:2572-7.
16. 16. SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension: final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA. 1991;265:3255-64.
17. 17. Buri VL, Culter JA, Higgins M, et al. Trends in the prevalence, awareness, treatment, and control of hypertension in the adult US population: data from the Health Examination Surveys, 1960 to 1991. Hypertension. 1995;26:60-9.
18. 18. Croog SH, Kong BW. Levine S, Weir MR. Baume RM. Saunders E. Hypertensive black men and women: quality of life and effects of antihypertensive medications. Arch Intern Med. 1990;150:1733-41.
19. 19. Saunders E, Shulman NB, eds. Hypertension in Blacks: Epidemiology, Pathophysiology and Treatment. Chicago III: Year Book Medical Publishers. 1985:17-36.
20. 20. Report of the Task Force on Black and Minority Health. Cardiovascular and Cerebrovascular Disease, Part 2. Washington. DC: US Dept. of Health and Human Services; 1986;IV:I-1-21.
21. 21. The Australian therapeutic trial in mild hypertension: report by the Management Committee. Lancet. 1980;1:1261-7.
22. 22. Medical Research Council trial of treatment of hypertension in older adults: principal results. BMJ. 1992;304:405-12.
23. 23. Perry HM Jr, Smith WM, McDonald RH, et al. Morbidity and mortality in the Systolic Hypertension in the Elderly Program (SHEP) pilot study. Stroke 1989;20:4-13.
24. 24. Casiglia E, Spolaore P, Mazza A, et al. Effect of two different therapeutic approaches on total and cardiovascular mortality in a cardiovascular study in the elderly. Jpn Heart J. 1994;35:589-600.
25. 25. Staessen JA, Fagard R, Thijs L, et al, for the Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Randomised double-blind comparison of placebo und active treatment for older patients with isolated systolic hypertension. Lancet. 1997;350:757-64.
26. 26. Gueyffier F, Boutitie F, Boissel JP, et al. INDANA: a meta-analysis on individual patients data in hypertension. Therapie. 1995;50: 353-62.
27. 27. Amery A, Birkenhager W, Broxko P, et al. Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial. Lancet. 1985;1:1349-54.
28. 28. Coope J, Warrender TS. Randomised trial of treatment of hypertension in elderly patients in primary care. BMJ. 1986;293:1145-51.
29. 29. Dahlof B, Lindholm LH, Hansson L, Scbersten B, Ekbom T. Wester PO. Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension]. Lancet. 1991: 338(8778):1281-5.
30. 30. Stanford JL, Hartge P, Brinton LA, Hoover RN, Brookmeyer R. Factors influencing the age at natural menopause. J Chronic Dis. 1987;40:995-1002.
31. 31. Whelan EA, Sandler DP. McConnaughey DR, Weinberg CR. Menstrual and reproductive characteristics and age at natural menopause. Am J Epidemiol. 1990;131;625-32.
32. 32. US Dept. of Commerce, Economics, and Statistics Administration and Bureau of the Census. Vital Statistics: Statistical Abstract of the United States: 1991. 11th ed. Washington, DC: US Government Printing Office; 1991:84.
33. 33. Rajkumar SV, Sampathkumar P, Gustafson AB. Number needed to treat is a simple measure of treatment efficacy for clinicians. J Gen Intern Med. 1996;11:357-9.
34. 34. Sinclair JC, Bracken MB. Clinically useful measures of effect in binary analysis of randomized trials. J Clin Epidemiol. 1994;47:881-9.
35. 35. Cook RJ, Sackett DL. The number to treat: a clinically useful measure of treatment. BMJ. 1995;310:452-4.
36. 36. McQuay HJ, Moore RA. Using numerical results from systematic reviews in clinical practice. Ann Intern Med. 1997;126:712-20.
37. 37. Helgeland A. Treatment of mild hypertension: a five year controlled drug trial - the Oslo Study. Am J Med. 1980;69:725-32.
38. 38. Kuramoto K, Matsushita S, Kuwajima I. Murakami M. Prospective study on the treatment of mild hypertension in the aged. Jpn Heart J. 1981;22:75-85.
39. 39. Wolff FW, Lindeman RD. Effects of treatment in hypertension: results of a controlled study. J Chronic Dis. 1966;19:227-40.
40. 40. Veterans Administration Cooperative Study Group on Antihypertensive Agents. Effects of treatment on morbidity in hypertension: results in patients with diastolic blood pressures averaging 115 through 129 mm Hg. JAMA. 1967;202:116-22.
41. 41. Veterans Administration Cooperative Study Group on Antihypertensive Agents. Effects of treatment, II: results in patients with diastolic blood pressures averaging 90 through 114 mm Hg. JAMA. 1970;213:1143-52.
42. 42. Evaluation of drug treatment in mild hypertension. VA-NHLBI feasibility trial. Plan and preliminary results of a two-year feasibility trial for a multicenter intervention study to evaluate the benefits versus the disadvantages of treating mild hypertension. Prepared for the Veterans Administration-National Heart, Lung, and Blood Institute Study Group for Evaluating Treatment in Mild Hypertension. Ann NY Acad Sci. 1978;304:267-92.
43. 43. Wikstrand J, Warnold I, Olsson G, Tuomilehto J, Elmfeldt D, Berglund G. Primary prevention with metoprolol in patients with hypertension: mortality results from the MAPHY study. JAMA. 1988;259:1976-82.
44. 44. Wilhelmsen L, Berglund G, Elmfeldt D, et al. Beta-blockers versus diuretics in hypertensive men: main results from the HAPPHY trial. J Hypertens. 1987;5:61-72.
45. 45. Multiple Risk Faetor Interventton Trial Research Group. Multiple Risk Factor Intervention Trial: risk factor changes and mortality results. JAMA. 1982;248:1465-77.
46. 46. Smith WM. Treatment of mild hypertension: results of a ten-year intervention trial. Circ Res. 1977;40:198-105.
47. 47. Barraclough M, Joy M, MacGregor G, et al. Control of moderately raised blood pressure: report of a co-operative randomized controlled trial. BMJ. 1973;3:434-6.
48. 48. Sprackling ME, Mitchell JR. Short AH, Watt G. Blood pressure reduction in elderly: a randomised controlled trial of methyldopa. BMJ. 1981;283:1151-3.
49. 49. Davis BR, Cutler JA, Gordon DJ, et al. Rationale and design for the Antihypertensive and Lipid Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). Am J Hypertens. 1996;9:342-60.
50. 50. Malacco E, Gnemmi AE, Romagnoli A, Coppini A, for the SHELL Study Group. Systolic hypertension in the elderly: long-term lacidipine treatment - objective, protocol, and organization. J Cardiovase Pharmacol. 1994;23(suppl 5):S62-6.
51. 51. Dahlof B, Devereux R, de Faire U, et al, for the LIFE Study Group. The Losartan Intervention For Endpoint reduction (LIFE) in Hypertension study: rationale, design, and methods. Am J Hypertens. 1997;10:705-13.
52. 52. Wing LM, Reid CM, Ryan P, et al, for the Management Committee on behalf of the High Blood Pressure Research Council of Australia. Second Australian National Blood Pressure Study (ANBP2). Australian Comparative Outcome Trial of ACE inhibitor-and diuretic-based treatment of hypertension in the elderly. Clin Exp Hypertens. 1997;19:779-91.
53. 53. Lindholm LH, Hansson L, Dahlof B, et al. The Swedish Trial in Old Patients with Hypertension-2 (STOP-hypertenston-2): a progress report. Blood Press. 1996;5:300-4.
54. 54. Neaton JD. Grimm RH Jr, Prineas RJ, et al. Treatment of Mild Hypertension Study: final results. JAMA. 1993;270:713-24.
55. 55. Hannson L. The BBB [Behandla Blodtryck Battre] Study: the effect of intensified antihypertensive treatment on the level of blood pressure, side-effects, morbidity and mortality in "well-treated" hypertensive patients. Blood Press. 1994;3:248-54.
56. 56. The IPPPSH Collaborative Group. Myocardial infarctions and cerebrovascular accidents in relation to blood pressure control. J Hypertens. 1985;Suppl 3:5513-8.
57. 57. Hansson L, Zanchetti A, Carruthers SG, et al, for the HOT Study Group. Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial. Lancet. 1998;351:1755-62.
58. 58. Estacio RO, Jeffers BW, Hiatt WR, Biggerstaff SL, Gifford N, Schier RW. The effect of nisoldipine as compared with enalapril on cardiovascular outcomes in patients with non-insulin-dependent diabetes and hypertension. N Engl J Med. 1998;338:645-52.
59. 59. Tatti P, Pahor M, Byington RP, et al. Outcome results of the Fosinopril Versus Amlodipine Cardiovascular Events Randomized Trial [FACET) in patients with hypertension and NIDDM. Diabetes Care. 1998;21:597-603.
60. 60. Feibach NH, Hebert PR, Stampfer MJ, et al. A prospective study of high blood pressure and cardiovascular disease in women. Am J Epidemiol. 1989;130:646-54.
61. 61. Nielsen WB, Vestbo J, Jensen GB. Isolated systolic hypertension as a major risk factor for stroke and myocardial infarction and an unexploited source of cardiovascular prevention: a prospective population-based study. J Hum Hypertens. 1995;9:175-80.
62. 62. Sigurdsson JA, Bengtsson C, Lapidus L, Lindquist O, Rafnsson V. Morbidity and mortality in relation to blood pressure and antihypertensive treatment: a 12-year follow-up study of a population sample of Swedish women. Acta Med Scand. 1984;215: 313-22.
63. 63. Perlman JA, Wolf PH, Ray R, Leiberknecht G. Cardiovascular risk factors, premature heart disease, and all-cause mortality in a cohort of northern California women. Am J Obstet Gynecol. 1988; 158:1568-74.
64. 64. Lever AF, Ramsay LE. Treatment of hypertension in the elderly. J Hypertens. 1995;13:571-9.
65. 65. MacMahon S, Rodgers A. The effects of blood pressure reduction in older patients: an overview of five randomized controlled trials in elderly hypertensives. Clin Exp Hypertens. 1993;15:967-78.
66. 66. Gueyffier F, Bulpitt C, Boissel JP, et al. Antihypertensive drugs in very old people: a subgroup meta-analysis of randomised controlled trials. Lancet. 1999;353(9155):793-6.
67. 67. Staessen JA, Fagard R, Thijs L, et al. Subgroup and per-protocol analysis of the randomized European Trial on Isolated Systolic Hypertension in the Elderly. Arch Intern Med 1998;158:1681-91.
68. 68. Jackson R, Barham P, Bills J, et al. Management of raised blood pressure in New Zealand: a discussion document. BMJ 1993;307: 107-10.
69. 69. Alderman MH. Blood pressure management: individualized treatment based on absolute risk and the potential for benefit. Ann Intern Med. 1993;119:329-35.
70. 70. Johannesson M, Dahlof B, Lindholm LH, et al. The cost-effectiveness of treatment hypertension in elderly people - an analysis of the Swedish Trial in Older Patients with Hypertension (STOP Hypertension). J Intern Med. 1993;234:317-23.
71. 71. Johannesson M. The impact of age on the cost-effectiveness of hypertension treatment: an analysis of randomized drug trials. Med Decis Making. 1994;14:236-44.
72. 72. Kannel WB, Wolf PA. Pulling it all together: changing the cardiovascular outlook. Am Heart J. 1993;123:264-7. Editorial.
73. 73. Anderson KM, Wilson PW, Odell PM, Kannel WB. An updated coronary risk profile: a statement for health professionals. Circulation. 1991;83:356-62.