Chromobacterium viscosum lipase catalyzes the transesterifications at the carboxyl site as well as the hydroxy site during the enzymatic enantioselective alcoholysis of O-acylated mandelates

Biotechnology Letters

Volumn 21, Issue 11, 1999, Pages 1023-1027

  Miyazawa, Toshifumi ^a   Kurita, Sota ^a   Ueji, Shinichi ^b   Yamada, Takashi ^a  

^a KONAN UNIVERSITY   (Japan)

^b KOBE UNIVERSITY   (Japan)

Author keywords

Chromobacterium viscosum; Enantioselective alcoholysis; Lipases; O acylated mandelates; Transesterification

Indexed keywords

ALCOHOL; MANDELIC ACID DERIVATIVE; TRIACYLGLYCEROL LIPASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHEMICAL REACTION; CHROMOBACTERIUM; DEACYLATION; ENZYME MECHANISM; ESTERIFICATION; NONHUMAN; REACTION ANALYSIS; STEREOCHEMISTRY;

CHROMOBACTERIUM VISCOSUM;

EID: 0033451007     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005650600997     Document Type: Article

References (7)

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4. Coppola GM, Schuster HF (1997) α-Hydroxy Acids in Enantioselective Syntheses, Weinheim: VCH, pp. 137-165.
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7. Miyazawa T, Shimaoka M, Yamada T (1999b) Resolution of 2-cyano-2-methylalkanoic acids via porcine pancreatic lipase-catalyzed enantioselective ester hydrolysis: effect of the alcohol moiety of the substrate ester on enantioselectivity. Biotechnol. Lett. 21: 309-312.