Resolution of 2-cyano-2-methylalkanoic acids via porcine pancreatic lipase-catalyzed enantioselective ester hydrolysis: Effect of the alcohol moiety of the substrate ester on enantioselectivity

Biotechnology Letters

Volumn 21, Issue 4, 1999, Pages 309-312

  Miyazawa, Toshifumi ^a   Shimaoka, Masanori ^a   Yamada, Takashi ^a  

^a KONAN UNIVERSITY   (Japan)

Author keywords

2 Cyano 2 methylalkanoic acids; Enantioselectivity; Ester hydrolysis; Optical resolution; Porcine pancreatic lipase

Indexed keywords

ALCOHOL; ALKANOIC ACID; ESTER; TRIACYLGLYCEROL LIPASE;

ARTICLE; ENANTIOMER; HYDROLYSIS;

EID: 0032904610     PISSN: 01415492     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1005472329251     Document Type: Article

References (8)

1. Chen C-S, Fujimoto Y, Girdaukas G, Sih CJ (1982) J. Am. Chem. Soc. 104: 7294-7299.
2. Dhaon MK, Olsen RK, Ramasamy K (1982) J. Org. Chem. 47: 1962-1965.
3. Miyazawa T, Takitani T, Ueji S, Yamada T, Kuwata S (1988) J. Chem. Soc. Chem. Commun.: 1214-1215.
4. Miyazawa T, Iwanaga H, Ueji S, Yamada T, Kuwata S (1989) Chem. Lett.: 2219-2222.
5. Miyazawa T, Mio M, Watanabe Y, Yamada T, Kuwata S (1992) Biotechnol. Lett. 14: 789-794.
6. Miyazawa T, Minowa H, Miyamoto T, Imagawa K, Yanagihara R, Yamada T (1997) Tetrahedron: Asymmetry 8: 367-370.
7. Murata M, Achiwa K (1991). Tetrahedron Lett. 32: 6763-6766.
8. Yamada S, Achiwa K (1966). Kagaku 21: 474-484.